| 盐酸大观霉素溶析结晶过程模拟与分析 |
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| 引用本文： | 鲍颖,王静康,王永莉.盐酸大观霉素溶析结晶过程模拟与分析[J].中国化学工程学报,2005,13(2):191-196. |
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| 作者姓名： | 鲍颖 王静康 王永莉 |
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| 作者单位： | [1]SchoolofChemicalEngineeringandTechnology,TianjinUniversity,Tianjin300072,China [2]SchoolofChemicalEngineeringandTechnology,TianjinUniversity,Tianjin300072,China／／Post-DoctoralStationofTianjinEconomicandTechnologicalDevelopmentArea,Tianjin300457,China |
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| 摘 要： | A mathematical model for dilution crystallization of spectinomycin dihydrochloride pentahydrate was established on the basis of the population and mass balance. Three operating modes, i.e., constant mass rate addition of diluent, constant mass fraction of diluent and constant size-independent growth rate, were investigated over a wide range of controlled parameters. The intrinsic characteristics of the crystallization process and the influence of operation parameters were analyzed in detail. Suitable strategy for better performance was suggested.
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| 关 键 词： | 模拟分析技术 稀释法 结晶化行为 奇霉素 二盐酸化物 |
| 修稿时间： | |
Simulation Analysis of Dilution Crystallization of Spectinomycin Dihydrochloride Pentahydrate |
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| BAO Ying,WANG Jingkang,Wang Yongli.Simulation Analysis of Dilution Crystallization of Spectinomycin Dihydrochloride Pentahydrate[J].Chinese Journal of Chemical Engineering,2005,13(2):191-196. |
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| Authors: | BAO Ying WANG Jingkang Wang Yongli |
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| Affiliation: | School of Chemical Engineering and Technology,Tianjin University,Tianjin 300072,China;Post-Doctoral Station of Tianjin Economic and Technological Development Area,Tianjin 300457,China;School of Chemical Engineering and Technology,Tianjin University,Tianjin 300072,China |
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| Abstract: | A mathematical model for dilution crystallization of spectinomycin dihydrochloride pentahydrate was established on the basis of the population and mass balance. Three operating modes, i.e., constant mass rate addition of diluent, constant mass fraction of diluent and constant size-independent growth rate, were investigated over a wide range of controlled parameters. The intrinsic characteristics of the crystallization process and the influence of operation parameters were analyzed in detail. Suitable strategy for better performance was suggested. |
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| Keywords: | spectinomycin dihydrochloride pentahydrate dilution crystallization mathematical model |
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