| 异丙酚配伍芬太尼或曲马多用于无痛人工流产术的效果比较 |
| |
| 引用本文： | 张华丹,王立昌,张英,魏薇.异丙酚配伍芬太尼或曲马多用于无痛人工流产术的效果比较[J].矿产勘查,2010(1):71-74. |
| |
| 作者姓名： | 张华丹 王立昌 张英 魏薇 |
| |
| 作者单位： | 北京大学深圳医院麻醉科,广东深圳518036 |
| |
| 摘 要： | 目的比较异丙酚配伍芬太尼或曲马多应用于无痛人工流产术的效果。方法ASAI-Ⅱ级人工流产术患者100例，随机分为5组（各20例），A组单纯静脉注射异丙酚2．5mg·kg；B组静脉注射芬太尼1ug·kg-1后静脉注射异丙酚2mg·kg-1；C组静脉注射芬太尼1．5ug·kg-1后静脉注射异丙酚1．5mg·kg-1；D组静脉注射曲马多1mg·kg-1后静脉注射异丙酚2mg·kg-1；E组静脉注射曲马多2mg·kg-1后静脉注射异丙酚2mg·kg-1。各组麻醉成功后均行人工流产术，监测各组术中血压（BP）、心率（HR）、脉搏血氧饱和度（SpO2）等生命体征，记录术中异丙酚使用剂量、麻醉时间（意识消失到呼之睁眼）、术毕唤醒时间、苏醒期有无躁动及术后有无下腹痛等。结果B组、c组分别与A组比较，SpO2〈90％例数增加（P〈0．05与P〈0．01），异丙酚剂量减少（P〈0．01），术后下腹痛减轻（P〈0．01）；C组与B组比较，SpO2〈90％的例数差异无统计学意义（P〉0．05），异丙酚剂量减少（P〈0．01），术后下腹痛差异无统计学意义（P〉0．05）。D组、E组分别与A组比较，SpO2〈90％例数及异丙酚剂量都一样（P〉0．05），术后下腹痛减轻（P〈0．05）。麻醉时间及术毕唤醒时间，C组短于A组、B组（P〈0．01）；B—E组的苏醒期躁动较A组少（P〈0．05）。结论无痛人工流产术中，异丙酚配伍芬太尼或曲马多都可增强术后镇痛、减少术毕躁动的发生率；且以异丙酚2mg·kg-1配伍芬太尼1ug·kg-1或曲马多1mg·kg-1为较佳选择。
|
| 关 键 词： | 人工流产术 异丙酚 芬太尼 曲马多 |
Comparison of Propofol Combined with Fentanyl or Tramadol Used for Artificial Abortion Painlessly |
| |
| ZHANG Hua-dan,WANG Li-chang,ZHANG Ying,WEI Wei.Comparison of Propofol Combined with Fentanyl or Tramadol Used for Artificial Abortion Painlessly[J].Mineral Exploration,2010(1):71-74. |
| |
| Authors: | ZHANG Hua-dan WANG Li-chang ZHANG Ying WEI Wei |
| |
| Affiliation: | (Department of Anesthesiology, the Shenzhen Hospital of Peiking University, Shenzhen 518036 ,China) |
| |
| Abstract: | Objective To compare effects of propofol combined with fentanyl or tramadol used for artificial abortion painlessly. Methods One hundred ASA I -- II artificial abortion patients were randomized into 5 groups（20 cases per group）. They were administrated introveneously with frags. Group A was administrated with 2. 5 mg . kg-1 of propofol only. Group B was with 1 ug . kg-1 of fentanyl and 2 mg . kg-1 of propofol. Group C was with of 1.5 ug . kg-1 fentanyl and 1.5 mg. kg-1 of propofol Group D was with ling . kg-1 of tramadol and 2.0 mg . kg-1 of propofol. Group E was with 2 mg . kg-1 of tramadol and 2 mg . kg-1 of propofol. Then artificial abortion was performed. Vital signs such as BP, HR and SpO2 were monitored. Propofol consumption, anaesthesia time, awaken time after operation, restlessness and post-operative hypogastric pain were recorded. Results Compared with Group A respectively,number of SpO2〈90% in Groups B and C increased （P〈0.05 and P〈0.01）,propofol consumption decreased （P〈0.01） and post-operative hypogastric pain a ttenuated（P〈0.01）. Compared with Group B,Group C had same rate of SpO2〈90%（P〉0.05） ,decreased propofol consumption （P〈0.01） and same post-operative hypogastric pain（P〉0.05）. Groups D and E had same number of SpO2〈90% and same propofol consumption with Group A （P〉0.05）. Compared with Group A,post-operative hypogastric pain in Group D and E reduced respectively（P〈0.05）. Anaesthesia time and awaken time in Group C were shorter than in Group A and B（P〈0.01）. Group B to E had less restlessness number than Group A（P〈0.05）. Conclusion When fentanyl or tramadol are used for artificial abortion, post-operative analgesia is enforced and rate of restlessness is decreased. Propofol 2 mg . kg-1 combined with fentanyl 1 ug . kg-1 or tramadol 1 mg . kg-1 show better selections. |
| |
| Keywords: | artificial abortion propofol fentanyl tramadol |
| 本文献已被 维普 等数据库收录！ |
|
