三苯二(口恶)嗪化合物的研究与应用进展(二)——三苯二(口恶)嗪系染料的研究进展

综述了三苯二(口恶)嗪化合物作为染料的合成工艺与性能特点,对三苯二(口恶)嗪类活性染料的研究及应用技术进行了评述。有50篇参考文献。     

三苯二(口恶)嗪化合物的研究与应用进展(一) --三苯二(口恶)嗪系衍生物结构、光谱性能及用作颜料的研究进展

本文用简明的基态和激发态之间的跃迁模型讨论了三苯二(口恶)嗪化合物的电子结构与可见光吸收光谱的关系.对三苯二(口恶)嗪化合物作为颜料的合成工艺进行了评述.     

三苯二(口恶)嗪电子光谱的溶剂效应

本文测试了两个三苯二(口恶)嗪化合物在19种溶剂中的电子光谱。发现化合物的可见吸收光谱的两个吸收带的v_(max)分别与溶剂的存在着良好的线性关系。     

三苯二噁嗪化合物的研究与应用进展(二)--三苯二(口恶)嗪系染料的研究进展

综述了三苯二噁嗪化合物作为染料的合成工艺与性能特点,对三苯二噁嗪类活性染料的研究及应用技术进行了评述.有50篇参考文献.     

非水溶性三苯二噁嗪系染(颜)料研究进展

一、前言三苯二噁嗪为母体的蓝色活性染料的出现,改变了长期以来以蒽醌为母体蓝色活性染料的一统地位,引起了国内外的高度重视,这方面工作见前文。本文主要讨论以三苯二(口恶)嗪为母体的非水溶性染(颜)料的研究进展。非水溶性三苯二(口恶)嗪化合物同样具有高发色强度和优良的光化学稳定性的特点,而且有些结构化合物具有较强的荧光性质,可作为染料或颜料用于纺织、涂料、印刷及光能转换、激     

三苯二噁嗪化合物的研究与应用进展（一）——三苯二噁嗪系衍生物结构、光谱性能及用作颜料的研究进展

本文用简明的基态和激发态之间的跃迁模型讨论了三苯二(口恶)嗪化合物的电子结构与可见光吸收光谱的关系。对三苯二(口恶)嗪化合物作为颜料的合成工艺进行了评述。     

三苯二恶嗪型活性艳蓝的合成与应用

合成了新型三苯二恶嗪活性艳蓝染料，该染料具有色光鲜艳、应用性能良好的特点。     

近年来国外三苯二恶嗪活性染料的研究进展及未来展望

本文着重介绍了１９８７～１９９５年国外在三苯二恶嗪活性染料方面研究的进展状况，并预见了其发展前景。     

三苯二恶嗪荧光染料的合成与电子光谱性能

本文以４－氨基－４－苯基二苯醚和４－氨基－２－苯基二苯醚与四氯苯醌反应,合成了两个新结构三苯二恶嗪荧光染料。在五种肿瘤剂中测定了它们的吸收及荧光光谱,并讨论了溶剂极性对染料荧光光谱影响。     

三苯二噁嗪化合物的研究与应用进展(二)--三苯二噁嗪系染料的研究进展

综述了三苯二噁嗪化合物作为染料的合成工艺与性能特点，对三苯二噁嗪类活性染料的研究及应用技术进行了评述。有50篇参考文献。     

Sunflower volatiles involved in honeybee discrimination among genotypes and flowering stages

In order to define the part of olfactory cues in the selective behavior of honeybees, observation on their foraging behavior was carried out on various sunflower genotypes in parallel with chemical analysis of aromatic extracts of the genotypes. Foragers show a preference for the early stages of flowering and, when they are given a choice between couples of parental lines of two commercial hybrids, Marianne and Mirasol, they are randomly distributed on Mirasol parents, but they prefer the female line of Marianne. The comparison of relative proportions of compounds among aromagrams obtained from head space trapping from the two couples of genotypes, reveals (1) a phenological stage effect for 17 compounds among 144 indexed compounds for Marianne lines and for 18 among 136 indexed compounds of Mirasol lines; most of these compounds exhibit higher relative proportions in the early flowering stages, which is related to plant attractiveness towards honeybees; (2) a sex effect for 33 compounds among 144 for Marianne lines and for 14 compounds among 136 for Mirasol lines; further semiquantitative analyses reveal a sex effect for only eight compounds of 134 for Marianne lines and 20 compounds of 250 for Mirasol lines, which represents less than 10% of the indexed compounds. These discriminatory compounds were partly identified by coupled GC-MS. Possible relations between such phenological and genotypical volatile fluctuations and forager attraction are discussed.     

Therapeutic Phytogenic Compounds for Obesity and Diabetes

Natural compounds have been used to develop drugs for many decades. Vast diversities and minimum side effects make natural compounds a good source for drug development. However, the composition and concentrations of natural compounds can vary. Despite this inconsistency, half of the Food and Drug Administration (FDA)-approved pharmaceuticals are natural compounds or their derivatives. Therefore, it is essential to continuously investigate natural compounds as sources of new pharmaceuticals. This review provides comprehensive information and analysis on natural compounds from plants (phytogenic compounds) that may serve as anti-obesity and/or anti-diabetes therapeutics. Our growing understanding and further exploration of the mechanisms of action of the phytogenic compounds may afford opportunities for development of therapeutic interventions in metabolic diseases.     

Correlation of closed-cup flash points with normal boiling points for silicone and general organic compounds

A correlation has been developed between closed-cup flash points and normal boiling points for silicone compounds. In addition, a more general correlation has been developed between these two properties for the general organic compounds, including silicone compounds. The closed-cup flash points can be predicted using empirical equations. The standard errors of estimate are 11.06 and 11.66°C for silicone compounds and general organic compounds (including silicone compounds), respectively. © 1997 John Wiley & Sons, Ltd.     

Quantitative Estimate Index for Early-Stage Screening of Compounds Targeting Protein-Protein Interactions

Drug-likeness quantification is useful for screening drug candidates. Quantitative estimates of drug-likeness (QED) are commonly used to assess quantitative drug efficacy but are not suitable for screening compounds targeting protein-protein interactions (PPIs), which have recently gained attention. Therefore, we developed a quantitative estimate index for compounds targeting PPIs (QEPPI), specifically for early-stage screening of PPI-targeting compounds. QEPPI is an extension of the QED method for PPI-targeting drugs that models physicochemical properties based on the information available for drugs/compounds, specifically those reported to act on PPIs. FDA-approved drugs and compounds in iPPI-DB, which comprise PPI inhibitors and stabilizers, were evaluated using QEPPI. The results showed that QEPPI is more suitable than QED for early screening of PPI-targeting compounds. QEPPI was also considered an extended concept of the “Rule-of-Four” (RO4), a PPI inhibitor index. We evaluated the discriminatory performance of QEPPI and RO4 for datasets of PPI-target compounds and FDA-approved drugs using F-score and other indices. The F-scores of RO4 and QEPPI were 0.451 and 0.501, respectively. QEPPI showed better performance and enabled quantification of drug-likeness for early-stage PPI drug discovery. Hence, it can be used as an initial filter to efficiently screen PPI-targeting compounds.     

稀土化合物作为高分子材料热稳定剂的研究进展

稀土化合物作为高分子热稳定剂具有优良的长期热稳定性,无毒环保,与其它热稳定剂具有协同作用。本文主要介绍了稀土热稳定剂在聚氯乙烯、硅橡胶和天然橡胶上的应用,概述了稀土与其它热稳定剂的协同作用与机理,并对稀土热稳定剂的应用和研究前景进行了展望。     

4,6-二甲氧基嘧啶衍生物的合成及生物活性测定

以4,6-二甲氧基-2-甲基磺酰基嘧啶为起始原料,采用中间体衍生化方法,合成了三类嘧啶类化合物.应用氢核磁共振、红外和元素分析验证了所合成化合物的结构.生物活性测试结果显示大部分化合物具有杀菌活性,其中化合物8在25 mg/L质量浓度下对水稻稻瘟病的抑制率达100%,化合物10c在400 mg/L质量浓度下对黄瓜霜霉病具有100%的防效.部分化合物具有一定的除草活性.     

噻唑类杀虫剂的研究进展

目前杂环化合物的发展呈现出多元化的趋势,其中噻唑类化合物是近年来发展的一个新亮点。尤其噻唑基团引入到各种不同的化合物结构中,通过结构修饰能产生一系列具有广谱生物活性化合物,使得它在新型超高效农药创制中发挥出越来越重要的作用。本文从杀虫方面对噻唑化合物的生物活性研究进行了综述,重点介绍了该类化合物的一些生物活性研究方面的工作,简述了不同取代基团对噻唑类衍生物生物活性的影响,并对它的发展趋势和应用前景作了展望。     

Neutral compounds from male castoreum of North American beaver,Castor canadensis

North American beavers (Castor canadensis) mark their territories with castoreum, the strong-smelling paste in their castor sacs. In their own territories, beavers respond with scent marking to experimental scent marks that consist of strange castoreum (or selected components). In part, the unique odor of castoreum is due to large amounts of phenolic compounds and neutral compounds. Purified neutral compounds were analyzed by GC. GC-MS, and NMR; identities of the neutral compounds were confirmed by comparing the properties of authentic compounds with those of the isolated compounds. We identified 13 neutral compounds that had not been reported before for castoreum. Most of these are oxygen-containing monoterpenes. Of the nine neutral compounds reported by Lederer (1949), only three are confirmed in our analysis; the other six neutral compounds are either absent or are not volatile enough to be detected by our methods. Eight compounds—6-methyl-l-heptanol, 4,6-dimethyl-l-heptanol, isopinocamphone, pinocamphone, two linalool oxides, and their acetates—were synthesized for structure identification and bioassays.     

Ozone Assisted Biological Treatment Of Industrial Wastewaters Containing Biorefractory Compound

Ozone pretreatment studies of organic compounds that are difficult to biodegrade were conducted to evaluate the effects of ozonation on biodegradability of these compounds. Initial testing was conducted in batch activated sludge experiments with and without preozonation to evaluate the impacts of ozonation on the ultimate BOD/COD and ultimate BOD/TOC ratios of these compounds. Experimental results indicated wastewater preozonation to be an effective pretreatment step for some compounds, ineffective for other compounds and detrimental to biological treatment of still other compounds. These same compounds were then investigated in continuous flow, complete–mix activated sludge systems. Complete material balances, including influent, effluent, waste sludge and off–gas specific compound analyses, were conducted so that the actual fate of the compound could be determined. Removal mechanisms of the ozonated or unozonated compound were then determined to be biodegradation, stripping, or sorption to the biomass. Three compounds were investigated: acrylonitrile, 2,4 dinitrophenol, and 1,2 dichloropropane.     

二元羧酸为配体制备的钨钼复合物催化氧化环戊烯

通过引入不同的二元羧酸（草酸、丙二酸和酒石酸）作为配体制备出各种钨和钼复合物，并采用元素分析、FT-IR和TG-DSC表征手段测定钨钼复合物的化学组成，探讨了复合物的存在形式。当含钨复合物用于催化氧化环戊烯时，草酸和丙二酸为配体制备的含钨复合物催化氧化环戊烯，产物环戊烯环氧化物的收率分别为53.41%和80.91%；当以草酸、丙二酸和酒石酸为配体时，制备的含钼复合物为催化剂催化氧化环戊烯（CPE），产物环戊烯环氧化物(CPO)的收率分别为72.30%、69.59%和16.44%。