Status of total shoulder arthroplasty

Some patients with degenerative, rheumatoid, and traumatic diseases of the glenohumeral joint require treatment primarily to relieve pain. In the absence of complete knowledge of basic mechanical requirements, clinical trials with both constrained and resurfacing prosthesis were initiated. Three types of constrained prostheses were placed in 23 patients. Pain relief was satisfactory, but six reoperations were necessary and motion greater than 90 degrees was rarely achieved. Twenty-five prostheses that were used to replace the glenohumeral articulation, but were not stable by virtue of design, were implanted. Again, pain relief was excellent; mechanical problems were not present, and motion was almost always greater than 90 degrees. Achieving stability by capsular-muscle cuff repair has not been as great a problem as anticipated. These results suggest that more emphasis should be placed on repair of the glenohumeral stabilizing structures than on their replacement.     

Rehabilitation following surgical procedures to address articular cartilage lesions in the knee

Knowledge of the structure and function of articular cartilage is important when considering rehabilitation following surgical procedures for articular cartilage lesions of the knee. Articular cartilage is avascular and derives its nutrition primarily from synovial fluid, resulting in a limited potential for regeneration. Basic science evidence has demonstrated that compressive loading may have a positive impact on articular cartilage healing; however, excessive shear loading may be detrimental. Rehabilitation following surgical procedures for articular cartilage lesions should include controlled range of motion exercises. Exercises to enhance muscle function must be done in a manner which minimizes shear loading of the joint surfaces in the area of the lesion. A period of protected weight bearing is often necessary and should be followed by progressive loading of the joint. This article will: 1) provide a brief review of the structure and function of articular cartilage lesions as it relates to rehabilitation; 2) describe common surgical procedures to address articular cartilage lesions; and 3) provide guidelines for rehabilitation following surgical management of articular cartilage lesions.     

Clinical implications of secondary impingement of the shoulder in freestyle swimmers

Swimming has become a popular recreational activity as well as a highly competitive sport in the United States. The repetitive nature of swimming can predispose the shoulder to mechanical impingement and microtrauma, which may lead to laxity, rotator cuff fatigue, and subsequent secondary impingement. Improper stroke mechanics can place the swimmer's shoulder at further risk. The purpose of this paper is to describe the pathology of secondary impingement in freestyle swimmers and to discuss the clinical implications for rehabilitation of swimmers with the pathology. A thorough subjective and objective evaluation is necessary to design a successful rehabilitation program. The rehabilitation program for swimmers with secondary impingement includes modification of training, flexibility, range of motion, strengthening, and mobilization as indicated. Functional and proprioceptive training may also be useful techniques in the rehabilitation of swimmer's shoulder. Improper stroke mechanics can also have clinical implications on swimmer's shoulders with secondary impingement. The clinical implication of secondary impingement in freestyle swimmers suggests that the primary goal of rehabilitation is to promote equilibrium of the shoulder complex while accounting for the demands of the sport.     

Dexamethasone abolishes the activation by nerve growth factor of protein kinase N: effects of nerve growth factor and dexamethasone on protein kinase N

Post-operative therapeutic rehabilitation in ligamentous-capsular injuries has a great importance and for the final result it is as the very operation. We begin it from making the patient realize that the good final result can be obtained only with patient, persistence and discipline. Early therapeutic rehabilitation after surgical treatment of ligamentous-capsular injuries is possible only when the ligament was reconstructed in a motor stable way. Painless, dosed, passive motion exercises with a limited range of movements did on a mechanical splint TELOS have a great importance for the final results.     

Golden standard: patellar tendon-plasty--technique and management of postoperative complications]

ACL reconstruction with a patellar tendon autograft has reached a high grade of perfection. Surgery can be performed mini-open or arthroscopically, both techniques are presently equal in morbidity and results. The optimal insertion areas for the graft have been defined and can be controlled intra- and postoperatively by radiographs. The bone blocks of the graft allow for stable fixation and an aggressive functional rehabilitation program stressing active full extension of the joint. Disadvantages are a certain donor site morbidity and a rate of restrictions in range-of-motion. The management of arthrofibrosis should address the pathogenesis. Localized arthrofibrosis is caused by a mechanical conflict in the knee and removal of the mechanical block will usually solve the problem. Generalized arthrofibrosis is a complex process involving the entire joint and resulting in a wide-spread proliferative reaction of the connective tissue. The surgical management must be more complex involving open debridement and capsulotomies.     

Initial heme uptake from albumin by short-term cultured rat hepatocytes is mediated by a transport mechanism differing from that of other organic anions

Twenty-eight proximal phalangeal fractures secondary to low-velocity gunshot wounds in 27 patients treated by stable fixation were retrospectively reviewed. Definitive fixation was performed within 1 week of injury. Fractures were stabilized with either a plate, intramedullary spacer, or a combination of both. When necessary, supplemental fixation was achieved with cerclage wires or interfragmentary screws. Twenty fractures with bone loss or comminution were primarily supplemented with iliac crest bone graft. After surgery, the fingers were splinted in 90 degrees of metacarpophalangeal (MP) flexion. An aggressive supervised therapy program was initiated within 24 hours of surgery. The average length of follow-up care was 9 months (range, 3-29 months). Primary union was achieved in all fractures. The average range of motion was 83 degrees for the MP joint and 66 degrees for the proximal interphalangeal joint. The average total active motion (TAM) for the involved digits was 200 degrees (range, 65 degrees-250 degrees). Fractures without intra-articular extension had a significantly better average TAM (213 degrees) than did those with intra-articular extension (169 degrees; p = .05). Primary bone grafting did not adversely effect the final TAM. There were no infections. Early stable fracture fixation of these injuries achieved union, alignment, and early rehabilitation with no appreciable increase in morbidity.     

Effect of inpatient rehabilitation measures on patients with total hip endoprostheses--evaluation 15 months after operation

159 patients were examined approximately 15 months after hip arthroplasty. 116 of these patients have had at that time point a postoperative 4 week hospital stay for rehabilitation. A score that considered pain at motion and at rest, maximal walking capacity and activity of daily living was used for evaluation. The preoperative conditions did not differ between patients that had their postoperative hospital stay for rehabilitation (n = 116) and those that did not (n = 43). The results at the time of examination were regarded as excellent (group 1; score 3) in 64 (40.3%) patients, as good (group 2; score 4) in 56 (35.2%) patients and as poor (group 3; score > or = 5) in 39 (24.5%) patients. The amount of patients with a hospital stay for rehabilitation was significantly (p = 0.025) higher in the patient groups with excellent or good results in comparison with the patients with poor postoperative outcome. The most excellent results were obtained in patients who had their rehabilitation within the first two months after surgery (p = 0.008). Apart from the above mentioned score the following-additionally assessed-parameters differed significantly between the 3 groups: hip mobility; pain elicited by pressure on the operated joint; pain in the contralateral hip or knee joints; consumption of analgetics; walking time for 15 meters; degree of handicap as assessed by the patient or the occupational therapist or the physician; coping with household activities (for females only). We conclude that a poor result of hip arthroplasty may be due not only to degenerative joint disease of the lower limbs but also (or in combination) to the lack of a postoperative hospital stay for rehabilitation.     

Volkmann's ischemic contracture of the upper extremity

Upper extremity deformity of ischemic contracture usually includes elbow flexion, forearm pronation, wrist flexion, thumb flexion and adduction, digital metacarpophalangeal joint extension, and interphalangeal joint flexion. Treatment of mild contractures consists of either nonoperative management with a comprehensive rehabilitation program (to increase range of motion and strenght) or operative management consisting of infarct excision or tendon lengthening. Treatment of moderate-to-severe contractures consists of release of secondary nerve compression, treatment of contractures (with tendon lengthening or recession), tendon or free-tissue transfers to restore lost function, and/or salvage procedures for the severely contracted or neglected extremity.     

Orthotics and rehabilitation for chronic hemophilic synovitis of the ankle. An overview

The ankle is the second most affected joint in hemophilia. Recurrent bleeding leads to chronic synovitis. Prevention of chronic synovitis should start with prophylactic replacement therapy or on demand treatment of recurrent hemarthrosis. Attention must be given to the function of the ankle joint. When instability is present, an extensive range of exercises is important. An orthotic or shoe adaption may be useful during the rehabilitation process. Viscoheels worn in shoes seem to reduce the bleeding frequency and pain.     

Joint center longitudinal positions computed from a selected subset of Chandler's data

Mathematical models of the human body are indispensable tools for studying the biomechanics of human movement. The geometrical centers of the 12 main joints (shoulders, elbows, wrists, hips, knees ankles), modeled as simple mechanical joints, are widely used as reference points for building mathematical models of the human body. These reference points, typically defined as "joint centers", are assumed to maintain a fixed 3D position relative to both the segments forming the joint, throughout the range of joint motion. No single point in a human joint perfectly meets this assumption, and no simple method is available for locating the points that are closest to meet it. Researchers often have recourse to subjective methods, based on their knowledge of anatomy. Objective estimates are easily attainable if the positions of a few bony landmarks can be measured on the subject, and the longitudinal distances of the joint centers from these landmarks are known. A subset of the anthropometric measurements performed by Chandler et al. (NTIS No. AD 710-622, 1975) on six cadavers was critically selected and utilized to compute the percent longitudinal distances of the 12 main joint centers from neighboring bony landmarks, relative to the lengths of the respective proximal and/or distal segments. Three-dimensional positions are attainable as well, by assuming joint centers lay on the respective segment longitudinal axes. The use of a method for accurately locating joint centers is recommended, particularly when they are used as reference points for defining a personalized geometrical model of a subject's body.     

Three-dimensional joint range of motion measurements from skeletal coordinate data

Frequently, joint range of motion is reported for a single plane (eg., sagittal, coronal, or transverse). However, the arc of joint motion during functional activities and many clinical tests encompasses motion in all three planes simultaneously. The purposes of this paper are to discuss a method to obtain relative joint three-dimensional angular displacement measurements using coordinates from skeletal landmarks and provide an analytical example of the method using three-dimensional angular displacement of the knee joint as a model. In order to calculate the three-dimensional relative motion, an orthogonal reference frame for each bone needs to be established. To establish the local reference frame, three noncollinear points are used to define unit vectors that are mutually perpendicular. Three-dimensional angles can be determined to describe the magnitude of the moving body rotation angles about the X, Y, and Z axes. These angles indicate the relative motion of body segments for abduction/adduction, flexion/extension, and internal/external rotation. The technique provides a more vigorous biomechanical understanding of joint motion and may have implications for measuring patient progress and evaluating joint mobilization treatment. This technique may also serve as a basis for developing new evaluation and treatment techniques.     

Gait biomechanics are not normal after anterior cruciate ligament reconstruction and accelerated rehabilitation

PURPOSE: Accelerated rehabilitation for anterior cruciate ligament (ACL) injury and reconstruction surgery is designed to return injured people to athletic activities in approximately 6 months. The small amount of empirical data on this population suggests, however, that the torque at the knee joint may not return until 22 months after surgery during walking and even longer during running. Although the rehabilitation has ended and individuals have returned to preinjury activities, gait mechanics appear to be abnormal at the end of accelerated programs. The purpose of this study was to compare lower extremity joint kinematics, kinetics, and energetics between individuals having undergone ACL reconstruction and accelerated rehabilitation and healthy individuals. METHODS: Eight ACL-injured and 22 healthy subjects were tested. Injured subjects were tested 3 wk and 6 months (the end of rehabilitation) after surgery. Ground reaction force and kinematic data were combined with inverse dynamics to predict sagittal plane joint torques and powers from which angular impulse and work were derived. RESULTS: The difference in all kinematic variables between the two tests for the ACL group averaged 38% (all P < 0.05). The kinematics were not different between the ACL group after rehabilitation and healthy subjects. Angular impulses and work averaged 100% difference for all joints (all P < 0.05) between tests for the ACL group. After rehabilitation, the differences between injured and healthy groups in angular impulse and work at both the hip and knee remained large and averaged 52% (all P < 0.05). CONCLUSIONS: Results indicated that after reconstruction surgery and accelerated rehabilitation for ACL injury, humans walk with normal kinematic patterns but continue to use altered joint torque and power patterns.     

Degenerative changes in the human cricoarytenoid joint

OBJECTIVE: Changes in the human voice occur during the natural aging process. Occurrence of compromising alterations in the cricoarytenoid joint has been hypothesized as a possible reason for voice changes seen in advanced age and has been discussed controversially until today. METHODS: The present study analyzes degenerative changes in 42 cricoarytenoid joints from 21 body donors (13 men and 8 women; age range, 42-98 years) by means of histological, immunohistochemical, and scanning electron microscopic methods. RESULTS: Many patients older than 40 years show distinctly altered joint surfaces at varying levels of intensity. The articular cartilage surface is fibrillated in some places. Chondrocytes near the joint surface appear as voluminous chondrocyte clusters. The superficial cartilage layer shows a positive reaction to type III and type I collagen antibodies. CONCLUSIONS: Chondrocyte proliferation next to the joint surface, changed collagen synthesis, and fibrillation of the joint surface indicate degenerative alterations. Such changes are well known in cases of limb diarthroses. The changes may impair gross positional or postural movements of the arytenoid cartilages and reduce the degree and extent of vocal ligament closure. The structural changes may also lead to negative functional consequences during vocal production, such as impaired vocal quality and reduced vocal intensity due to air leakage through incompletely or loosely approximated vocal ligaments.     

Characterization of the enzymatic 7-O-acetylation of sialic acids and evidence for enzymatic O-acetyl migration from C-7 to C-9 in bovine submandibular gland

BACKGROUND: Although the anticancer effects of progesterone therapy for patients with endometrial carcinoma are widely acknowledged, a detailed assessment of the resultant morphologic alterations in tumor tissue kinetics has hitherto been lacking. METHODS: Biopsy and hysterectomy specimens of 14 endometrial carcinomas (endometrioid-type) before and during progesterone therapy were studied to clarify changes in apoptosis and cell proliferation and their relation to morphologic alterations. The extent of squamous differentiation within tumor lesions was also examined. RESULTS: In the good-response group, tumor cells took on characteristics of normal endometrial gland cells in the secretory phase. A positive correlation between reduction in the mitotic index and the degree of morphologic alterations during hormone therapy was observed, but the frequency of apoptotic cells did not vary. In both the good-response and poor-response groups, development or enlargement of squamous areas was observed, in comparison with the initial biopsy specimens. CONCLUSIONS: These results suggest that prolonged progesterone administration can suppress cell proliferation in endometrial carcinomas through tumor cell differentiation without altering apoptosis, resulting in a shift in tissue kinetics toward a relative predominance of cell deletion. In addition, increases in the occurrence of squamous areas within tumors do not always appear to be related to treatment efficacy.     

The lunotriquetral joint: kinematic effects of sequential ligament sectioning, ligament repair, and arthrodesis

This experiment was conducted to study the effects of sequential sectioning of the ligaments of the lunotriquetral (LT) joint and the effects of simulated repair or arthodesis on kinematics of the wrist joint using an x-ray stereophotogrammetric technique. A 3-dimensional coordinate software program calculated relative motion between bodies as screw axis displacement and rotation about each axis. Sectioning of the proximal and dorsal component of the LT ligament had little effect on carpal kinematics, but sectioning of the proximal and palmar components of the ligament resulted in flexion of both the lunate and triquetrum, producing a volar intercalated segment instability (VISI) pattern. The triquetrum supinated away from the lunate after sectioning of the entire LT ligament. Greater VISI occurred after sectioning the dorsal radiotriquetral and scaphotriquetral ligaments. Progressive destabilization of the LT joint results in increasing kinematic alterations; however, these may not exactly mimic the clinical situation. Moving the wrist through 1,000 cycles increased the instability. Dorsal repair of the LT ligament realigned the lunate and triquetrum, and LT fusion corrected triquetral supination. The latter, however, resulted in overcorrection into extension, which prevented a full wrist extension. The repair used may be insufficient to restore the palmar ligamentous integrity. Lunotriquetral arthodesis was difficult to simulate, providing some insight into the cause of clinical nonunions. Severe VISI is not correctable by repair or arthrodesis and requires further study using reconstructive procedures not discussed here.     

Open versus closed kinetic chain exercise: issues in rehabilitation after anterior cruciate ligament reconstructive surgery

What has been called "closed kinetic chain" (CKC) exercise has become popular in the last 5 to 10 years for use after anterior cruciate ligament (ACL) reconstructive surgery. Closed kinetic chain exercises appear to have gained popularity over more traditionally used open kinetic chain (OKC) exercises because many clinicians believe that CKC exercises are safer and more functional. These clinicians also contend that CKC exercise is equally effective as OKC exercise in restoring quadriceps femoris muscle force production following ACL reconstructive surgery. The purpose of this clinical perspective is to examine the evidence concerning OKC and CKC training after ACL reconstructive surgery with regard to these issues and discuss how physical therapists can best apply this knowledge in clinical practice. Based on the review of data, it does not appear that clinicians should completely abandon more traditional OKC exercises and replace them with CKC exercises in postoperative ACL reconstruction rehabilitation programs. Both types of exercise apparently can be modified to minimize (1) the risk of applying excessive strain on the ACL graft and (2) the risk of excessive patellofemoral joint stress. Depending on the functional goals of the patient, both OKC and CKC exercises may be appropriate for simulating functional activities. When improvement in quadriceps femoris muscle function is an essential treatment goal, therapists may need to combine OKC exercises with CKC exercises to provide optimal training stimuli. Suggestions for further research are discussed. [Fitzgerald GK. Open versus closed kinetic chain exercise: issues in rehabilitation after anterior cruciate ligament reconstructive surgery.     

Cytosolic sialidase from pig brain: a ''protein complex'' containing catalytic and protective units

Extension block splinting (EBS) at the proximal interphalangeal joints of the fingers is a common technique for both primary treatment of reduced dorsal dislocations/fracture-dislocations at that joint and as a rehabilitation method following open reduction of such injuries. It is seldom realized that the method is a classic example of two orthopedic principles: stable arc splinting and early protected motion. As a primary treatment technique, following reduction of the dislocation, EBS is exemplary for an ideal group of cases, competitive for a marginal group of cases, and often unsatisfactory for a questionable group of cases. Demarcation between the groups is made, and the technique of EBS is reviewed.     

Evaluation of the efficacy of thiamine and pyridoxine in the treatment of symptomatic diabetic peripheral neuropathy

Our purpose in this study was to determine the effects of cheilectomy on the mechanics of dorsiflexion of the first metatarsophalangeal (MTP) joint. Ten fresh-frozen cadaver feet were utilized, of which two demonstrated radiographic evidence of hallux rigidus. Each specimen was rigidly mounted on a custom-made slide tray that was articulated with a hinge mechanism designed to dorsiflex the first MTP joint. Range-of-motion measurements were made on the first MTP joint. Cheilectomy of 30% of the metatarsal head diameter was performed. Lateral radiographs with the beam centered on the MTP joint were taken with the joint at neutral, 20 degrees, 40 degrees, and at the limits of dorsiflexion. This process was repeated after a 50% cheilectomy was performed. The radiographs were examined for changes in joint congruence and in patterns of surface motion as the hallux moved from neutral to full dorsiflexion. Instant centers of rotation were determined by a method first described by Rouleaux. We constructed surface velocity vectors to describe patterns of motion of the first MTP joint. The mean dorsiflexion of the first MTP joint was 67.9 degrees and increased to 78.3 degrees after 30% cheilectomy. The increase in dorsiflexion was significantly greater in the two specimens with hallux rigidus (33%) than in the other specimens (12.1%). After both levels of cheilectomy, the proximal phalanx demonstrated pivoting at the resection site on the metatarsal head. This pivoting resulted in abnormal motion patterns across the MTP joint. Normal sliding motion predominated in early dorsiflexion, with compression peaking at the end stage of dorsiflexion, producing jamming of the articular surfaces. Cheilectomy significantly increased dorsiflexion of the MTP joint, but resulted in abnormal motion patterns. The increase in dorsiflexion resulted from pivoting of the proximal phalanx on the metatarsal head, resulting in anomalous velocity vectors and compression across the MTP joint.