共查询到19条相似文献,搜索用时 140 毫秒
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聚天冬氨酸(PASP)水凝胶由于其良好的生物相容性、生物降解性及吸水、保水性引起了众多科研工作者的关注。本文首先综述了PASP水凝胶的合成方法,并对比了各自的优势和不足。在此基础上,介绍了本文作者课题组开发的水相均相交联工艺,此工艺具有污染小、成本低的优势,并初步实现了工业化生产,产品的吸水倍率可达300~1000g/g。此外,本文还综述了PASP水凝胶的共混/共聚改性及其在农业及生态修复、环境保护的应用,并着重介绍了PASP的结构可设计性及其在生物医学领域的相关应用研究。其中,本文作者课题组针对PASP水凝胶的吸水保水特性,持续开展了其作为农林保水剂的研究,并得到了良好的试验结果,为大规模应用提供了有益的参考。最后针对PASP性能、合成工艺和应用领域的关联性,归纳了PASP水凝胶亟待解决的问题。本文的阐述将为PASP水凝胶的合成、应用和推广等研究工作提供指导和参考。 相似文献
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聚天冬氨酸(PASP)是一种可生物降解的水溶性氨基酸聚合物,在工业领域应用广泛,是一种很有发展前景的生物高分子材料。从20世纪90年代开始成为水处理药剂研究和开发的热点,在工业循环冷却水领域可以替代现在使用的聚丙烯酸,但其阻CaCO3垢,Ca3(PO4)2垢的能力都不突出,其应用受了很大限制。为改善聚天冬氨酸的阻垢性能,我们参考文献,用2.氨基乙醇与聚琥珀酰亚胺(PSI)反应,把羟基引入到PASP分子结构中合成了聚天冬氨酸的衍生物,并将其与药剂PBTCA复配,结果表明复配药剂具有很好的协同效应,具有良好的阻垢性能,因此可作为阻垢分散剂而广泛应用于循环冷却水处理中。 相似文献
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气体分离液晶膜的研究现状与展望 总被引:2,自引:0,他引:2
概述了气体分离液晶膜的材料精选,较系统地论述了液晶膜的富氧性能、气态烃分离性能,二氧化碳富集性能及抗气体渗透性能。指出液晶膜可望在医疗、精细化工、农业及包装等领域获得应用。 相似文献
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聚天冬氨酸的生物降解性能及降解机理研究 总被引:1,自引:0,他引:1
应用摇床实验法对所合成的聚天冬氨酸(PASP)的生物降解性能进行了系统研究,分析讨论了PASP浓度、分子量以及合成原料与其生物降解性能的关系。对分子量为5 400左右的PASP来说,当接种物浓度为10 mg/L,其浓度低于50 mg/L时,第4 d降解率就达到100%;但对接种物浓度为1 001.30 mg/L的试液来说,分子量为9 700左右的PASP的生物降解性能最好,第4 d降解率可达到82.1%;以铵盐B为原料的PASP生物降解性能最佳,在第20 d,降解率就达到100%;同时,对实验试液的氨氮值进行了测定,降解后试液的氨氮值均达到直接排放的要求标准。利用红外光谱对PASP进行了结构表征,并进一步探讨了PASP的生物降解机理,认为PASP的生物降解是生物物理降解与生物化学降解协同作用的结果。 相似文献
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随着合成材料工业的不断发展,高分子材料在机械工业、农业等领域有着广泛的应用。但一般高分子材料的防火性能不佳,需要通过添加阻燃剂来提高材料的抗燃性,从而降低火灾危险性,保证生命财产安全。对此,笔者主要分析了高分子材料阻燃剂的分类,探究了阻燃技术的应用与发展趋势。 相似文献
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台立民;姜滢;冯思静 《中国塑料》2010,24(2):1-5
综述了聚羟基烷酸酯(PHAs)在工业、农业、医药等不同领域中的应用状况。工业应用包括生产各类工业品、包装物和处理工业废水等;医药应用包括制作各类医疗器件和进行药物缓释释放等;农业应用包括生产农用薄膜、进行农药缓释和作物固氮等。此外,通过将PHAs与碳纳米管、蒙脱土等材料复合,可制成具有特殊应用性能的纳米复合材料。 相似文献
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聚天冬氨酸是一种新型的聚合氨基酸材料,具有很好的生物相容性、生物降解性。本文综述了聚天冬氨酸及其衍生物水凝胶的研究现状,介绍了化学交联、光交联、γ射线交联3种交联方法合成的聚天冬氨酸及其衍生物水凝胶,以及近年来聚天冬氨酸基凝胶对大分子蛋白药物、小分子抗炎性药物、抗癌和基因药物控释的研究进展,并对该凝胶在药物控释领域的发展方向进行了预测。 相似文献
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利用带负电的聚天冬氨酸分子与部分带正电的磷脂双分子层之间的静电吸附作用,通过"一步法"成功制备了聚天冬氨酸(PASP)修饰脂质体(PLPs),实现了修饰脂质体微酸环境响应性。将脂质体制备与PASP修饰同时完成的"一步法"大大简化了制备工艺,提高了脂质体(PLPs)的制备效率。通过单因素筛选确定了pH敏感性显著的修饰脂质体制备条件,即外水相溶液PASP浓度2.5%(质量分数),pH8.5。透射电子显微镜照片显示PLPs由于修饰剂的存在具有更大的粒径,且表面电负性高,证明了"一步法"成功制备了pH敏感性修饰脂质体。 相似文献
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Biodegradable poly(aspartic acid) (PASP) hydrogel and PASP/gelatin complex were prepared to evaluate their potential application as pH‐sensitive matrices for controlled protein release. Entrapment of myoglobin (Mb) and its release were compared between the two types of carriers. It was found that incorporation of Mb into PASP hydrogel strongly depended on the medium pH and NaCl concentration, and was time‐consuming. However, complete entrapment of Mb into PASP/gelatin complex was found within pH ranged from 2.5 to 4.0, which was concomitant with the formation of PASP/gelatin complex. By adjusting Mb feed ratio, Mb entrapment in the complex can be up to 31.54% (by weight) with high loading efficiency (96.2%). Gradual release of Mb from PASP hydrogel was observed within pH 2.0–7.4, while Mb release from PASP/gelatin complex was negligible within pH 2.0–4.2 for 4 days. In addition, pulsatile Mb release can be achieved by combining polyanhydride with pH‐sensitive PASP/gelatin complex, while the device composed of polyanhydride and PASP hydrogel is mechanically unstable. PASP/gelatin complex formed by electrostatic interactions is superior to the single‐component PASP hydrogel synthesized by chemical cross‐linking as pH‐sensitive matrices for controlled protein release when entrapment of proteins and pH‐sensitivity of protein release are concerned. © 2005 Wiley Periodicals, Inc. J Appl Polym Sci, 2006 相似文献
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Superabsorbent polyaspartic acid (PASP) resin was prepared from high molecular weight polysuccinimide (PSI), which was synthesized
from l-aspartic acid by thermal polycondensation. The effects of the reaction temperature, the reaction time, the concentration
of the solvent, the molecular weight of PSI, the concentration of the cross-linking agent, the hydrolysis conditions, and
the drying temperature on the swelling ratio of PASP resin were investigated. The swelling ratios of PASP resin in deionized
water and saline solution were measured, and the biodegradability of PASP hydrogel was evaluated. The results show that the
swelling ratios of PASP resin in deionized water were 100–1,120 g/g depending on the preparation conditions. The swelling
ratio of PASP resin in saline solution reached 143 g/g, and PASP resin was a kind of biodegradable material with high water
absorbency, so this PASP resin can be used as agricultural and horticultural water-holding material, and in manufacturing
of diapers, sanitary napkins, medical products, etc. 相似文献
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Rui Yuan Yanping Wu Pengfei Ju Li Ji Hongxuan Li Lei Chen Huidi Zhou Jianmin Chen 《应用聚合物科学杂志》2019,136(37):47939
Graphene oxide (GO) can improve the mechanical property of polymer matrix greatly. However, its poor dispersibility may considerably lower reinforcing efficiency. To address this problem, the environment-friendly polyaspartic acid (PASP) was adopted to modify GO through two generally modified methods: hydrogen bond adsorption and chemical graft modification. Findings indicate that the covalent bond grafted PASP–GO exhibits better dispersibility than the product by noncovalent method (PASP/GO-noncovalent). For chemically grafted PASP–GO, the nearly spherical polymer nanoparticles are formed on the GO nanosheets through self-polymerization, and its size can be well manipulated by adjusting the dosage of PASP so as to yield PASP–GO-1/4, PASP–GO-1/2, and PASP–GO-1/1 (mass ratio: mPASP/mGO = 1/4, 1/2, and 1/1); the corresponding diameters of these polymer aggregates are 56.4 ± 7.1, 90.1 ± 12.6, and 151.2 ± 16.1 nm. They are further utilized to reinforce polyimide matrix. Compared with the PASP–GO-1/2 and PASP–GO-1/1, the smaller PASP–GO-1/4 has better strengthening effect, due to its high specific surface area and dense distribution. This desirable fabrication of GO-based nanofillers provides a new avenue on the development of polymer matrix with comprehensive performances. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2019 , 136, 47939. 相似文献