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疏松砂岩储层渗透率变化范围大,压裂液滤失表现出较大差异。针对疏松砂岩储层压裂液滤失难以估量的问题,开展静态滤失实验研究不同胍胶浓度压裂液在不同压差环境下的滤失规律,确定滤失系数与压差关系。首先开展滤纸滤失实验,研究压裂液滤失对滤失压差的依赖性,随后针对疏松砂岩渗透率变化范围大的特点开展岩板滤失实验,探索岩板渗透率对压裂液滤失特性的影响。结果表明:压裂液的滤饼滤失系数与压差的幂指数成正比,与胶粉浓度的倒数平方根成正比。 相似文献
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采用沸石和砾石构建生态滤坝,研究不同组配方式下生态滤坝的污染物去除效果,同时将铁碳微电解技术引入生态滤坝,研究铁碳生态滤坝对微污染河水水质净化效果。结果表明,混合滤坝的NH3-N和TN的平均去除率比分层滤坝分别高9.75个和8.01个百分点,说明基质混合生态滤坝的污染物去除效果更好。铁碳生态滤坝的COD、NH3-N、NO2--N、TN的平均去除率分别比混合滤坝提高18.68个、4.17个、15.56个和8.99个百分点,说明添加铁碳可以增强生态滤坝对COD和TN等污染物的去除能力。通过微生物群落结构及多样性分析,铁碳滤坝微生物群落多样性较高,优势菌为假单胞菌属和狭义梭菌属。 相似文献
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杨传武 《中国石油和化工标准与质量》2012,32(1):147
在采油过程中,钻井液起到重要的作用,但钻井液的滤失性能是钻井液的主要性能,对稳固井壁起到重要的作用,本文主要从静滤失、动滤失、瞬时滤失等三个方面综述了井内钻井液的滤失性能。 相似文献
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R. Subramanian M. Nakajima A. Yasui H. Nabetani T. Kimura T. Maekawa 《Journal of the American Oil Chemists' Society》1999,76(10):1247-1253
The first step in the process of vegetable oil refining is degumming, in which phospholipids and mucilaginous gums are removed
that otherwise result in a low-grade oil. A membrane process is remarkably simple yet potentially offers many advantages in
degumming. Studies were conducted on surfactant-aided membrane degumming with soybean and rapeseed oils in a magnetically
stirred flat membrane batch cell with different types of microfiltration membranes. The reduction of phospholipids in soybean
oil was in the range of 85.8–92.8% during the membrane process. The phosphorus content of membrane permeates of soybean oil
was in the range of 20–58 mg/kg. Crude rapeseed oil contained higher amount of nonhydratable phospholipids and hence resulted
in lower reduction in phospholipids, in the range of 66.4–83.2%. Addition of hydratable phospholipids could improve the efficiency
of degumming in the membrane process without using any electrolyte, resulting in improvement of quality as well as quantity
of the phospholipids. 相似文献
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Yuji Tatemoto Masaya Tsunekawa Shuji Yano Takenari Takeshita Katsuji Noda 《Chemical engineering science》2007,62(8):2187-2197
A relatively large wet material was immersed in a fluidized bed of hygroscopic porous particle (silica gel beads) under reduced pressure. And then the drying characteristics were compared with those in the case of inert particle (glass beads). The comparison of drying characteristics is performed experimentally and theoretically. In calculation, the water transfer from the sample to the fluidized bed was considered. The calculation results are in good agreement with the experimental data. The effects of the operational conditions (the pressure in the drying chamber and the temperature of the drying gas) on the drying characteristics were also examined in both fluidizing particles.The drying finishes earlier in the case of hygroscopic porous particle than in the case of inert particle regardless of pressure in the drying chamber, since the water transfer from the sample facilitates the drying in the case of hygroscopic porous particles. The temperature decrement in drying appears in the case of inert particle. This phenomenon is also observed in the case of hygroscopic porous particle, but the decrement degree of the temperature is much smaller than that in the case of inert particle. The difference of the minimum temperature in the sample in drying between the cases of hygroscopic porous particle and inert particle is very slight for different pressures in the drying chamber. 相似文献
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污泥生物炭中氮硫元素含量高,其氮硫行为和环境效应对全球气候变化的影响不容忽视。以往的研究中,研究者往往以富碳生物炭作为主要研究对象,关注碳对全球气候变化的行为和功效,而对氮硫元素的作用关注不够。本文从原始污泥基本性质到其热解过程,再到生物炭的老化,逐步对污泥生物炭整个生命周期内氮硫的行为及其环境效应研究进行综述,并对未来应注重开展的研究方向进行展望,为生物炭中氮硫元素固定、释放及与之关联的环境效应和温室气体排放控制研究提供理论基础。分析表明,污泥中氮元素含量普遍高于硫元素,且热解过程中氮比硫更容易转移至气相产物。氮硫元素随热解温度的增加,在三相产物中的分配都是炭中持续减少,油中先增后减,气中一直增加。高温(>800℃)条件下,气相中的氮含量高于固相,而硫元素则仍然主要存在于固相中。污泥生物炭老化及其环境效应研究表明,污泥生物炭氮硫元素与土壤的相互作用及其温室效应问题在今后的研究中应引起重视。 相似文献
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Hugo G. Collantes Ernesto Gianoli Hermann M. Niemeyer 《Journal of chemical ecology》1999,25(3):491-499
The effect of defoliation and consecutive defoliation (condefoliation) of rye seedlings on the allocation patterns of biomass and hydroxamic acids (Hx) was evaluated five days after treatment. Growth of condefoliated seedlings was lower than that of defoliated and nondefoliated ones. Concentration of Hx decreased in shoots of condefoliated seedlings compared to nondefoliated ones, while concentration of Hx in root exudates increased. Allocation of Hx to roots and root exudates increased at the expense of allocation to the shoots in condefoliated seedlings. The ratio of Hx-aglucone to Hx-glucoside was higher in shoots of defoliated and condefoliated seedlings. The decrease in quantity of defense in shoots was accompanied by an increase in its quality, given that aglucones are more toxic than glucosides. The increase in concentration of Hx—an allelopathic compound also involved in mineral uptake by roots—in root exudates of condefoliated seedlings was suggested to lead to an advantage in the acquisition of resources for the regeneration of lost biomass. 相似文献
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Benoît Usunier Clment Brossard Bruno LHomme Christine Linard Marc Benderitter Fabien Milliat Alain Chapel 《International journal of molecular sciences》2021,22(4)
Fibrosis is a leading cause of death in occidental states. The increasing number of patients with fibrosis requires innovative approaches. Despite the proven beneficial effects of mesenchymal stem cell (MSC) therapy on fibrosis, there is little evidence of their anti-fibrotic effects in colorectal fibrosis. The ability of MSCs to reduce radiation-induced colorectal fibrosis has been studied in vivo in Sprague–Dawley rats. After local radiation exposure, rats were injected with MSCs before an initiation of fibrosis. MSCs mediated a downregulation of fibrogenesis by a control of extra cellular matrix (ECM) turnover. For a better understanding of the mechanisms, we used an in vitro model of irradiated cocultured colorectal fibrosis in the presence of human MSCs. Pro-fibrotic cells in the colon are mainly intestinal fibroblasts and smooth muscle cells. Intestinal fibroblasts and smooth muscle cells were irradiated and cocultured in the presence of unirradiated MSCs. MSCs mediated a decrease in profibrotic gene expression and proteins secretion. Silencing hepatocyte growth factor (HGF) and tumor necrosis factor-stimulated gene 6 (TSG-6) in MSCs confirmed the complementary effects of these two genes. HGF and TSG-6 limited the progression of fibrosis by reducing activation of the smooth muscle cells and myofibroblast. To settle in vivo the contribution of HGF and TSG-6 in MSC-antifibrotic effects, rats were treated with MSCs silenced for HGF or TSG-6. HGF and TSG-6 silencing in transplanted MSCs resulted in a significant increase in ECM deposition in colon. These results emphasize the potential of MSCs to influence the pathophysiology of fibrosis-related diseases, which represent a challenging area for innovative treatments. 相似文献
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In the present study we evaluated the uptake of ALA and its conversion to EPA + DHA in rats given linseed oil (LSO) in native form or as a microemulsion in whey protein or in lipoid. In a single oral dose study in which rats maintained on rodent pellets deficient in ω-3 fatty acids were intubated with 0.35 g LSO in lipoid, the amount of ALA present in lymph was increased reaching a maximum concentration of 16.23 mg/ml at 2.5 h. The amount of ALA present in lymph was increased to a maximum level of 10.95 mg/ml at 4 h in rats given LSO as a microemulsion in whey protein. When LSO was given without emulsification, the amount of ALA present in lymph was found to reach a maximum level of 7.08 mg/ml at 6 h. A similar result was observed when weaning rats were intubated with 0.15 g of LSO per day for a period of 60 days. Higher levels of ALA by 41 and 103 % were observed in lymph lipids of rats given microemulsions of LSO in whey protein and in lipoid respectively as compared to rats given LSO without pre-emulsification. Very little conversion of ALA to EPA and DHA was observed in lymph lipids but higher amounts of EPA + DHA was observed in liver and serum of rats given LSO in microemulsion form. This study indicated that ALA concentration in lymph lipids was increased when LSO was given in microemulsion form in lipoid and further conversion to EPA and DHA was facilitated in liver and serum. 相似文献
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Kawashima H Tateishi N Shiraishi A Teraoka N Tanaka T Tanaka A Matsuda H Kiso Y 《Lipids》2008,43(1):37-43
Disorders of the metabolism of essential fatty acids (EFAs) are related to atopic dermatitis (AD). Concentrations of dihomo-γ-linolenic
acid (DGLA), an EFA, in the serum of AD patients are lower than those in healthy volunteers. Recently we developed a fermented
DGLA oil, and examined whether oral administration of DGLA prevents development of dermatitis in NC/Nga mice, which spontaneously
develop human AD-like skin lesions. NC/Nga mice were fed a diet either containing or not containing DGLA for 8 weeks under
in air-uncontrolled conventional circumstances. Clinical skin severity scores were significantly lower in mice fed DGLA than
in mice not fed it. Scratching behavior and plasma total IgE levels were also reduced in the DGLA group, in association with
histological improvement. DGLA suppressed clinical severity of skin lesions dose-dependently, with an increase in DGLA contents
in phospholipids of skin, spleen, and plasma. Discontinuation of DGLA administration resulted in the onset of dermatitis and
a decrease in DGLA contents in skin, spleen, and plasma. These findings indicate that oral administration of DGLA effectively
prevents the development of AD in NC/Nga mice, and that DGLA in phospholipids is a compound of key importance in the development
and prevention of dermatitis. 相似文献
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Asfia Soomro Jackie Trink Kian ONeil Renzhong Li Safaa Naiel Bo Gao Kjetil Ask Joan C. Krepinsky 《International journal of molecular sciences》2021,22(6)
Diabetic kidney disease (DKD) is the leading cause of kidney failure. RhoA/Rho-associated protein kinase (ROCK) signaling is a recognized mediator of its pathogenesis, largely through mediating the profibrotic response. While RhoA activation is not feasible due to the central role it plays in normal physiology, ROCK inhibition has been found to be effective in attenuating DKD in preclinical models. However, this has not been evaluated in clinical studies as of yet. Alternate means of inhibiting RhoA/ROCK signaling involve the identification of disease-specific activators. This report presents evidence showing the activation of RhoA/ROCK signaling both in vitro in glomerular mesangial cells and in vivo in diabetic kidneys by two recently described novel pathogenic mediators of fibrosis in DKD, activins and cell-surface GRP78. Neither are present in normal kidneys. Activin inhibition with follistatin and neutralization of cell-surface GRP78 using a specific antibody blocked RhoA activation in mesangial cells and in diabetic kidneys. These data identify two novel RhoA/ROCK activators in diabetic kidneys that can be evaluated for their efficacy in inhibiting the progression of DKD. 相似文献
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The effect of a crack in the overlap region of an adhesive single lap joint is studied on the shear stress distribution in adhesive layer. Each adherend is considered to be a laminated composite material with unidirectional fibers aligned in the direction of the applied load. Crack location is selected to be in the top adherend laminate, in the form of cut fibers and matrix bays. The crack can occur in any layer. The shear-lag model is used to derive the equilibrium equations which are then solved by means of eigenvector expansion. The effects of adhesive thickness, crack size, and location in the adherend, total number of layers in each adherends, volume fraction of fibers, and type of fibers are investigated on the shear distribution in the adhesive as well as load distribution in the intact fiber at the crack tip located in the top adherend. The effect of dissimilar laminated adherends is also investigated on the adhesive shear stress distribution. According to the results, in the presence of a crack, the peak shear stress in the adhesive layer and load concentration in the fibers are very susceptible to the adhesive thickness and number of layers in laminated adherends. 相似文献