TiO_2 与TiO_2 -SiO_2 薄膜的表面性质及生物活性研究

采用溶胶 -凝胶法在医用NiTi形状记忆合金表面制备了TiO2 与TiO2 -SiO2 薄膜 .用X射线 (XRD) ,红外光谱 (FT -IR) ,X射线光电子能谱 (XPS)和原子力显微镜 (AFM)对薄膜的表面组成、结构与形貌进行了研究 .将表面涂有薄膜的试样浸入模拟体液 (SBF) ,用XPS分析Ca ,P在薄膜表面的沉积情况 .结果表明 :TiO2 -SiO2 膜具有比TiO2 膜更高的生物活性 ,主要原因是TiO2 -SiO2 薄膜表面存在较多的羟基基团 ,在模拟体液中诱导磷灰石沉积的能力较高 ;此外 ,薄膜的表面形貌对其生物活性也有一定的影响     

TiO2与TiO2—SiO2薄膜的表面性质及生物活性研究

采用溶胶－凝胶法在医用NiTi形状记忆合金表面制备了TiO2与TiO2-SiO2薄膜,用X射线（XRD）,红外光谱（FT－IR）,X射线光电子能谱（XPS）和原子力显微镜（AFM）对薄膜的表面组成,结构与形貌进行了研究,将表面涂有薄膜的试样浸入模拟体液（SBF）,用XPS分析Ca,P在薄膜表面的沉积情况,结果表明：TiO2-SiO2人有比TiO2膜更高的生物活性,主要原因是TiO2-SiO2薄膜表面存在较多的羟基基团,在模拟体液中诱导磷灰石沉积的能力较高,此外,薄膜的表面形貌对其生物活性也有一定的影响。     

预钙化加速类骨磷灰石在镍钛合金表面生长的电化学阻抗谱

通过酸碱处理活化NiTi合金表面,在模拟体液中仿生生长类骨磷灰石层以改善其生物相容性.采用电化学阻抗谱研究了预钙化对加速磷灰石沉积的影响,并基于双层模型建立了电子等效电路.结果表明:随着在模拟体液中浸泡时间的延长,化学处理的NiTi合金表面类骨磷灰石不断生长,并且添加预钙化试样浸泡3 d,即可在合金表面生长出均匀完整的类骨磷灰石层,而未预钙化试样表面沉积物稀少.对应电子等效电路中,预钙化试样电阻值明显大于未预钙化试样的,显示预钙化促进了活化NiTi合金表面类骨磷灰石的生长.     

热处理后TiO2纳米管涂层的生物活性

采用阳极氧化法在钛种植体表面制备了TiO2纳米管涂层。考察了450℃热处理对TiO2纳米管涂层相结构及在模拟体液中抗腐蚀能力的影响,并探讨了成骨细胞在TiO2纳米管涂层表面的生长行为。结果表明,热处理后TiO2纳米管涂层的抗腐蚀能力及生物活性都有了明显的提高。     

紫外辐照诱导等离子体喷涂氧化钛涂层的生物活性

采用大气等离子体喷涂技术在钛合金表面上制备常规和纳米结构TiO2涂层.考察了TiO2涂层经紫外光辐照后浸泡于模拟体液(simulatedbody fluid,SBF)中的生物活性.研究涂层表面状态、紫外光辐照时间和辐照介质对TiO2涂层生物活性的影响.结果表明:经紫外光辐照后的纳米TiO2涂 层在SBF中可诱导类骨磷灰石在其表面形成,显示了良好的生物活性,但常规TiO2涂层和磨去表面的纳米TiO2涂层无此种现象发生.紫外光辐照处 理时间增长有利于类骨磷灰右的生成.在SBF、水、空气中进行紫外光辐照的纳米TiO2涂层表面均有类骨磷灰石生成,但在水中进行紫外光辐照处 理的涂层显示较低的生物活性.     

相组成对TiO_2薄膜生物活性的影响(英文)

以钛酸正丁酯(Cl6H36TiO4)为原料,采用溶胶-凝胶法制备了TiO2薄膜。TiO2薄膜分别在300,400,500,600,800℃下于空气中热处理2h。将热处理前后的TiO2薄膜浸泡于模拟体液(simulated body fluids,SBF)中,考察其表面诱导类骨磷灰石形成的能力。利用X射线衍射、扫描电子显微镜、能谱仪、Fourier变换红外光谱等测试手段表征TiO2薄膜和磷灰石的微观结构。结果表明:原始和经300℃热处理的TiO2薄膜为无定形结构;随着煅烧温度的升高,TiO2由无定形结构向锐钛矿相转变;温度升高至800℃后,锐钛矿相完全转化为金红石相。TiO2薄膜经SBF浸泡7d后,经400,500,600,800℃热处理的TiO2薄膜表面生成含有碳酸根的羟基磷灰石,且其Ca与P的摩尔比为1.52,接近人体骨骼的钙磷比(1.67)。而原始和经300℃热处理的TiO2薄膜无此现象发生,这说明TiO2薄膜的晶型对其生物活性具有重要影响,锐钛矿和金红石相TiO2薄膜均具有诱导磷灰石生成的能力。     

生物医用氮化碳薄膜的力学性能比较研究

使用磁控溅射法在生物医用NiTi合金基体表面制备了Ti／TiN、Ti／DLC以及Ti／CNx梯度薄膜,利用扫描电镜研究了薄膜的截面形貌,并使用划痕仪及摩擦磨损仪研究比较了薄膜的力学性能。结果表明：薄膜均表面平整,与基底结合紧密。Ti／CNx薄膜与NiTi合金基底的结合力大于Ti／DLC薄膜,略低于Ti／TiN薄膜。3种梯度薄膜均能有效改善NiTi合金的耐磨损性能,其中,Ti／CNx薄膜拥有最低的摩擦系数和最完整的磨损表面,耐磨性最好。     

溶胶-凝胶法在医用Ti合金表面制备SiO2-CaO-MgO-P2O5系生物玻璃涂层

在医用Ti合金表面涂覆一层生物玻璃涂层可阻止金属离子的溶出并且提高其生物活性。本文采用溶胶-凝胶法在Ti合金基体上制备了Si02-CaO-MgO-P2O5系生物玻璃涂层。利用差示量热扫描仪（DSC）、扫描电镜（SEM）、拉伸试验和模拟体液（SBF）浸泡等手段系统研究了涂层的表面形貌，粘附性能及生物活性。结果表明：热处理温度为800℃时涂层与基体间的粘附强度最大，涂层越薄涂层与基体问的粘附强度越大；在模拟体液中浸泡30天后，材料表面生成了大量磷灰石。用溶胶-凝胶法可在Ti合金基体上制备出SiO2-CaO-MgO-P2O5系生物活性高的生物玻璃涂层。     

医用Ti合金表面生物玻璃涂层的制备与研究

在医用Ti合金表面涂覆一层生物玻璃涂层可阻止金属离子的溶出并且提高其生物活性。本文采用溶胶-凝胶法在Ti合金基体上制备了SiO2-CaO-MgO-P2O5系生物玻璃涂层。利用差示量热扫描仪(DSC)、扫描电镜(SEM)、拉伸试验和模拟体液(SBF)浸泡等手段系统研究了涂层的表面形貌、粘附性能及生物活性。结果表明:热处理温度为800℃时涂层与基体间的粘附强度最大,涂层越薄涂层与基体间的粘附强度越大;在模拟体液中浸泡30天后,材料表面生成了大量磷灰石。用溶胶-凝胶法可在Ti合金基体上制备出SiO2-CaO-MgO-P2O5系生物活性高的生物玻璃涂层。     

医用钛合金微弧氧化膜的制备及其生物相容性研究

利用微弧氧化技术在Ti合金表面制备了医用羟基磷灰石(HA)膜,研究了HA膜在模拟体液中的生物相容性,通过SEM观察了HA膜在模拟体液中浸泡不同时间的表面形貌,并利用EDs测试了HA膜浸泡前后的Ca、P原子分数.结果表明,HA膜在模拟体液中浸泡后,体液的pH变化不大,而经过溶解-重结晶,新生成的HA晶粒发育更完整,更利于...     

Effect of diamond-like carbon (DLC) on the properties of the NiTi alloys

NiTi alloy has found wide application in the biomedical field due to its unique shape memory effect, superelasticity and biocompatibility. However, the materials are vulnerable to surface corrosion and the most serious issue is out-diffusion of toxic Ni ions from the substrate into body tissues and fluids. In this paper, NiTi alloys were coated with diamond-like carbon (DLC) fabricated by plasma immersion ion implantation and deposition (PIIID) to improve their corrosion resistance and blood compatibility without sacrificing their shape memory effect and superelasticity. The structure of the films and the depth profiles between the films and substrate were studied using Raman spectroscopy and XPS, respectively. The phase transformation temperature, superelasticity, anticorrosion behavior and Ni ions release of the coated and uncoated sample were investigated by DSC, tensile tests, potentiodynamic polarization and AAS, respectively. The hemocompatibilty of the coated and uncoated samples was measured using clotting time and platelet adhesion. The results shows that the films is DLC accompanying with the formation of the mixing layer, and the DLC films can markedly improve the corrosion resistance and the hemocompatibility, obviously increase the ratio of albumin-to-fibrinogen and effectively block the Ni ions release of the NiTi alloys without sacrificing its superelasticity and changing its phase transformation temperature. The research results suggest DLC films prepared by PIIID could improve the in vivo performance of NiTi alloys implanted into the human body.     

镁合金表面锌系磷化膜及硅酸盐封闭工艺与性能

为提高镁合金的耐蚀性能,在镁合金表面制备锌系磷化膜,并对磷化膜进行封闭。比较了未封闭磷化膜、浸油封闭磷化膜、铬酸盐封闭磷化膜和硅酸盐封闭磷化膜的表面形貌、元素组成、厚度和耐蚀性能,结果表明:浸油封闭、铬酸盐封闭和硅酸盐封闭对镁合金表面磷化膜的厚度基本没有影响,但封闭前后磷化膜的表面形貌和元素组成有所不同。Cr、Na和Si元素分别通过形成化学转化膜、胶体状膜或物理填充孔隙被引入封闭后磷化膜中。硅酸盐封闭磷化膜的致密性相对较好,使镁合金的耐蚀性能得到有效提高。在铬酸盐封闭逐渐被弃用的趋势下,效果较好并且低污染环保的硅酸盐封闭在磷化膜封闭中具有应用潜力。     

镁合金表面锌系磷化膜及硅酸盐封闭工艺与性能

为提高镁合金的耐蚀性能,在镁合金表面制备锌系磷化膜,并对磷化膜进行封闭。比较了未封闭磷化膜、浸油封闭磷化膜、铬酸盐封闭磷化膜和硅酸盐封闭磷化膜的表面形貌、元素组成、厚度和耐蚀性能,结果表明:浸油封闭、铬酸盐封闭和硅酸盐封闭对镁合金表面磷化膜的厚度基本没有影响,但封闭前后磷化膜的表面形貌和元素组成有所不同。Cr、Na和Si元素分别通过形成化学转化膜、胶体状膜或物理填充孔隙被引入封闭后磷化膜中。硅酸盐封闭磷化膜的致密性相对较好,使镁合金的耐蚀性能得到有效提高。在铬酸盐封闭逐渐被弃用的趋势下,效果较好并且低污染环保的硅酸盐封闭在磷化膜封闭中具有应用潜力。     

Blood compatibilities of carbon nitride film deposited on biomedical NiTi alloy

Carbon nitride (CNx) film, diamond-like carbon (DLC) film, and titanium nitride (TiN) film were deposited on biomedical NiTi alloy substrates using direct current magnetron sputtering, respectively. In order to improve the adhesive strength between the deposited hard film and the NiTi alloy, a Ti transition layer was pre-deposited firstly. We emphatically evaluated the blood compatibilities of the NiTi alloy substrate and the deposited hard films by haemolysis test and platelet conglutination test. It was shown that the blood compatibilities of NiTi alloy can be improved effectively by the deposition of hard films. In comparison with TiN and DLC film, CNx film had the best surface modification effects covering the minimum haemolysis ratio and the best anticoagulation property.     

铝合金表面GPTMS硅烷膜的制备及耐蚀性能研究

为提高铝合金耐腐蚀力，运用正交试验法研究在铝合金表面制备 γ-（2，3-环氧丙氧）丙基三甲氧基硅烷（GPTMS）自组装膜最佳工艺条件，利用极化曲线和扫描电子显微镜研究该硅烷膜在铝合金表面的耐腐蚀性能。研究表明：最佳工艺条件为 100 mL溶液中， pH＝4. 5，V（GPTMS）∶V（EtOH）∶V（H₂O）= 2∶7∶91，T_{1（水解温度）}＝25 ℃，t_{1（水解时间）}＝7 h，t_{2（浸涂时间）}＝10 min，t_{3（固化时间）}＝90 min，T_{2（固化温度）}＝120 ℃，该工艺条件下制备的硅烷膜具有优异的耐腐蚀性能。     

Electropolishing and passivation of NiTi shape memory alloy

Electropolishing of NiTi alloy has been investigated. The influence of polishing bath composition and the operating conditions instead of the conditions of the process on the quality of the surface, evaluated by AFM and SEM methods, was established. Morphologically uniform surfaces were obtained only in the case of solutions containing hydrofluoric and sulfuric acids. Electropolished samples were sterilized and thermally passivated, then their corrosion resistance was measured in Tyrode's physiological solution. It was established that already after the electropolishing the corrosion resistance of NiTi alloy increases due to the spontaneously formed TiO₂ layer. The increase of the thickness of the layer during sterilization and thermal passivation causes further increase in the corrosion resistance.     

二氧化钛薄膜的制备及性能研究

二氧化钛具有无毒、光催化性能强,热稳定和化学结构稳定,耐腐蚀性能良好等特点,可作为半导体催化材料和耐腐蚀材料。二氧化钛薄膜可以采用物理的方法和化学的方法制备,薄膜态材料在未来将有着潜在的应用。本文结合近年来二氧化钛薄膜的研究进展,介绍了二氧化钛薄膜的制备方法和应用领域,并对未来二氧化钛薄膜的研究进行了展望。     

Effects of Ti ion deposition on corrosion resistance of WE43 alloy

Ti films with different thicknesses were successfully deposited on the surface of WE43 alloy by filtered cathode vacuum arc technology, and the microscopic morphology, structural composition, and corrosion resistance of the films were studied by means of X-ray diffractometer, X-ray photoelectron spectroscopy and scanning electron microscope. The results show that when the deposition time of Ti ions is 800 s, the thickness of the Ti film is 2.35 μm, the surface of the film is dense, and there are few defects. Meanwhile, Ti800 alloy has the best corrosion resistance among the four modified alloys. It has a corrosion current density (I_corr) of 2.9 μA·cm⁻², which is about 50 times lower than that of unmodified alloy. This conclusion is also confirmed by the complete film layer of Ti800 alloy and the tight bonding with the substrate after immersion experiments. Good corrosion resistance is attributed to a dense and relatively chemically stable TiO₂/Ti structure in simulated body fluid corrosive media.     

Controlling the degradation rate of bioactive magnesium implants by electrophoretic deposition of akermanite coating

In order to improve the corrosion resistance and the surface bioactivity of biodegradable magnesium alloys, a nanostructured akermanite (Ca₂MgSi₂O₇) coating was grown on AZ91 magnesium alloy through electrophoretic deposition (EPD) assisted with micro arc oxidation (MAO) method. The crystalline structures, morphologies and compositions of samples were characterized by X–ray diffraction, scanning electron microscopy and energy dispersive spectroscopy. The in vitro bio–corrosion (biodegradability) and bioactivity behaviors of samples were investigated by electrochemical and immersion tests. The experimental results indicated that the nanostructured akermanite coating could slow down the corrosion rate and improve the in vitro bioactivity of biodegradable magnesium alloy. Thus, magnesium alloy coated with nanostructured akermanite may be a promising candidate to be used as biodegradable bone implants.