医学图像中粘连细胞分割方法研究

研究粘连细胞图像的分割问题。针对医学细胞图像中,细胞经常发生粘连,细胞粘连部分由于发生像素灰度混合,造成图像不清晰。传统的应用灰度的分割算法由于不能很好的区分粘连部分的灰度,不能完整的分割细胞的问题。为了解决上述问题,提出了自适应阀值调整的粘连细胞分割方法。通过求得粘连部位的细胞像素的具体特征,运用阀值的自适应变化区分粘连部位像素之间的不同,对像素进行划分,克服了传统方法像素划分不清的弊端。实验表明,方法能够有效的分割医学图像中的粘连细胞,取得了比较好的效果。     

医学图片中分离重叠细胞的方法研究

该文研究的主要内容是处理粘连细胞的分割。在医学中所运用到的细胞图片,往往细胞和细胞之间会有粘连,由于粘连之后的部分经常出现灰度的叠加,这就造成图片信息的不准确,给研究造成了一定的干扰。传统的细胞分割方法因为在辨别粘连区域灰度的能力较差,所以在分割粘连细胞时往往有缺失。为了改善这样的问题,该文采用自适应阈值来处理粘连细胞的分割问题。计算得出细胞粘连区域像素的特征信息,利用自适应阈值来识别粘连区域中像素间的差异,把像素归类,使得传统分割算法混淆像素的问题得到很好的解决。通过实验可以得出,该文使用的自适应阈值分割粘连细胞的算法是有效的,效果理想。     

基于局部灰度占比的粘连细胞分割方法

针对医学细胞图像中的粘连现象,对采集到的细胞图像进行均值聚类、二值化、空洞填充、距离变换等预处理操作后,根据距离变换图像的像素灰度值来选取实现粘连细胞分割的最佳阚值,在分析重叠或粘连细胞图像的局部像素特征的基础上,对距离变换处理后图片的局部灰度占比分布进行了全面的分析和处理.实验结果表明,该方法简单易行,具有较好的分割效果.     

结合卷积神经网络和超像素聚类的细胞图像分割方法

针对细胞图像尺寸大、细胞形状各异,导致从图像中分割出精准的细胞十分困难的问题,以卷积神经网络为基础,结合染色校正方法和简单线性迭代的超像素聚类算法,提出了一种新的结构来进行细胞图像分割。首先,利用染色校正方法对细胞图像进行预处理,提高图像的颜色对比度;然后利用卷积神经网络获得初步分割结果;最后再将简单线性迭代聚类获得的超像素边界信息反馈到初分割图像上进行改进提升。提出的算法可以有效地减少图像局部信息的冗余,更准确地获得目标区域的边界位置。实验表明,本文提出的算法细胞分割准确率达到了92.72%,与经典卷积神经网络、阈值分割等其他细胞分割算法相比,具有更好的分割效果。     

精神分裂症脑区磁共振图像分割方法研究

研究精神分裂症人脑皮层脑区图像病变区域的准确分割问题。精神分裂症患者的人脑皮层脑区灰质密度与正常区域存在差异,但病变区域与正常区域血管粘连在一起,病变组织会发出更强烈的信号,在生成的图像中像素亮度极高,高亮度造成二者像素灰度差异过小。传统的基于边沿像素灰度差的图像分割方法,无法避免由于血管粘连造成的像素灰度差异过小的缺陷,分割准确度不高。提出了一种利用像素差值约束算法的人脑皮层脑区磁共振图像分割算法。通过约束病变区域分割的衡量区域标准,从而实现人脑皮层脑区磁共振图像的准确分割。实验证明,改进算法避免了血管粘连造成的像素灰度差异过小的缺陷,提高了图像分割的准确率,为精神分裂症脑区检测提供了依据。     

基于背景检测的图像分割方法

通过对阈值法单阀值和多阀值的研究,针对其难以处理包含多个前景物体的现状,提出了一种基于统计像素信息自适应地选择背景像素区域的图像分割方法.该方法采用单元格作为像素统计单位、直方图表示各层的像素分布情况,根据像素统计信息确定每一层的背景像素区域,通过相连层单元格背景像素相同或相近的关系自适应地在下一层直方图中修改背景像素区域.实验结果表明,该方法对于图像分割具有很好的通用性和有效性,是一种实用的、有前途的图像分割方法.     

基于组合的尿沉渣粘连细胞分割算法的研究与实现

在尿沉渣图像中经常会出现细胞重叠和粘连的现象。将粘连的细胞分离是尿沉渣自动检测系统中一项重要而困难的任务。针对这一情况,提出一种基于组合思想的分割算法。该算法首先利用改进的自适应阈值分割算法结合形态学处理对细胞进行定位得到子图像,然后再利用基于距离变换的分水岭算法对子图像进行粘连细胞分离。实验结果证明,该算法能准确、稳定地分割尿沉渣粘连细胞。同时,该算法明显地提高了尿沉渣自动检测系统的性能。     

基于自适应滤波的淋巴细胞图像分割算法研究

研究细胞图像分割精确度问题。针对现有医学细胞图像分割算法普遍存在噪声敏感、难以处理粘连细胞以及时间复杂度高等问题,提出基于自适应形态滤波增强的淋巴细胞图像分割算法AMWS。首先采用自适应形态滤波增强算法对淋巴细胞图像进行去噪增强,既去除噪声又保护细胞图像的细节,然后采用双阈值分割对细胞进行粗分割,对重叠细胞进行标记分水岭细分割,完成整个分割过程。仿真结果表明,AMWS算法能够较好地完成淋巴细胞图像的分割,有效避免了现有图像分割方法的缺陷,弥补了现有细胞分割算法的不足,分割效果优于目前同类分割算法。     

基于分水岭变换的目标图像的分割与计数方法

针对在图像分析中所获得的目标物体相互粘连的情况，利用分水岭变换的模拟浸水原理，提出了一种新的、有效的分水岭分割算法。算法只需考虑图片中像素的4连通和集水盆地的边缘情况即可，使得粘连物体得到了有效的切割和分离。统计各个所得盆地即可以得到实际物体的准确个数。该分割方法成功有效地解决了目标物体粘连而造成的不便和对后续处理的干扰等问题，同时把该算法用于对粘连物体的计数方面，使本来繁琐、复杂的图像物体计数变得十分简单、便捷。是一种切实可行的图像分割与计数方法。     

基于主凹点检测的血细胞图像去粘连分割算法研究

针对医学中血细胞图像研究中粘连细胞难以分割的问题,提出一种基于主凹点检测的分割算法。通过滤波预处理去除图像的噪声以改善图像质量,基于改进的活动轮廓模型初步提取细胞轮廓,通过寻找主凹点的方法准确定位粘连细胞凹点位置,标记并融合细胞图像轮廓、粘连形状等特性,实现粘连细胞分离。实验结果表明,该方法具有很好的分割准确度和完整度,且该算法具有普适性。     

煤矿井下安全监控分站的设计及其仿真实现

为了设计一种具有低成本、低功耗、易操作、功能强且可靠性高的煤矿井下安全分站,针对煤矿安全生产实际,文章提出了采用MCS-51系列单片机为核心、具有CAN总线通信接口的煤矿井下安全监控分站的设计方案;首先给出煤矿井下安全监控分站的整体构架设计,然后着重阐述模拟量输入信号处理系统的设计过程,最后说明单片机最小系统及其键盘、显示、报警、通信等各个组成部分的设计;为验证设计方案的可行性与有效性,使用Proteus软件对设计内容进行仿真验证,设计的煤矿井下安全监控分站具有瓦斯、温度等模拟量参数超标报警功能和电机开停、风门开闭等开关量指示功能;仿真结果表明:设计的煤矿井下安全监控分站具有一定的实际应用价值.     

View-based model-driven architecture for enhancing maintainability of data access services

In modern service-oriented architectures, database access is done by a special type of services, the so-called data access services (DAS). Though, particularly in data-intensive applications, using and developing DAS are very common today, the link between the DAS and their implementation, e.g. a layer of data access objects (DAOs) encapsulating the database queries, still is not sufficiently elaborated, yet. As a result, as the number of DAS grows, finding the desired DAS for reuse and/or associated documentation can become an impossible task. In this paper we focus on bridging this gap between the DAS and their implementation by presenting a view-based, model-driven data access architecture (VMDA) managing models of the DAS, DAOs and database queries in a queryable manner. Our models support tailored views of different stakeholders and are scalable with all types of DAS implementations. In this paper we show that our view-based and model driven architecture approach can enhance software development productivity and maintainability by improving DAS documentation. Moreover, our VMDA opens a wide range of applications such as evaluating DAS usage for DAS performance optimization. Furthermore, we provide tool support and illustrate the applicability of our VMDA in a large-scale case study. Finally, we quantitatively prove that our approach performs with acceptable response times.     

A pragmatic multi-method investigation of discrepant technological events: Coping,attributions, and ‘accidental’ learning

Discrepant technological events or situations that entail a problem, a misunderstanding or a difficulty with the Information Technology (IT) being employed, are common in the workplace, and can lead to frustration and avoidance behaviors. Little is known, however, about how individuals cope with these events. This paper examines these events by using a multi-method pragmatic approach informed by coping theory. The results of two studies – a critical incident study and an experiment – serve to build and test, respectively, a theoretical model that posits that individuals use a variety of strategies when dealing with these events: they experience negative emotions, make external attributions, and adopt engagement coping strategies directed at solving the event, eventually switching to a disengagement coping strategy when they feel they have no control over the situation. Furthermore, users’ efforts may result in ‘accidental’ learning as they try to overcome the discrepant IT events through engagement coping. The paper ends with a discussion of the results in light of existing literature, future opportunities for research, and implications for practice.     

The Distributed Time-Triggered Simulation Scheme: Core Principles and Supporting Execution Engine

Distributed real-time simulation is a young technology field but its practice is under increasing demands. In recent years the author and his collaborators have been establishing a new approach called the distributed time-triggered simulation (DTS) scheme which is conceptually simple and easy to use but widely applicable. The concept was initiated in the course of developing a new-generation object-oriented real-time programming scheme called the time-triggered message-triggered object (TMO) programming scheme. Some fundamental issues inherent in distributed real-time simulation that were learned during recent experimental studies are discussed along with some approaches for resolving the issues. An execution engine developed to support both the TMOs engaged in control computation and the TMOs engaged in DTS is also discussed along with its possible extensions that will enable significantly larger-scale DTSs.     

Software-Konfigurationsmanagement in großen Softwareprojekten

Zusammenfassung Mit zunehmender Größe der Softwaresysteme verschärfen sich die für die Software-Herstellung typischen Probleme: Beherrschen großer Objektmengen, Erhalten der Systemkonsistenz, Kontrolle der ständigen Änderungseinflüsse und Gewährleisten einer langen Lebensdauer. Die Disziplin Konfigurationsmanagement bildet den methodischen Ansatz, diese Probleme besser zu beherrschen. Software-Konfigurationsmanagement faßt die Herstellung von Softwaresystemen als eine Abfolge von kontrollierten Änderungen an gesicherten Zwischen- und Endergebnissen auf. Dargestellt werden die Objekte und Funktionen des Software-Konfigurationsmanagements sowie die hierfür in großen Software-Projekten benötigten Methoden, Instanzen und Hilfsmittel.     

Information for Authors

正http://www.zju.edu.cn/jzus http://www.springerlink.com Aim The Journals of Zhejiang University-SCIENCE(A/B/C)are edited by the international board of distinguished Chinese and foreign scientists,and are aimed to present the latest developments and achievements in scientific research in China and     

Editorial:Brain-machine interface(BMI) and cyborg intelligence

正Brain-machine interfaces(BMIs)aim at building a direct communication pathway between the brain and an external device,and represent an area of research where significant progress has been made during the past decade.Based on BMIs,mind information can be read out by neural signals to control     

Information for Authors

正http://www.zju.edu.cn/jzus http://www.springerlink.com Aim The Journals of Zhejiang University-SCIENCE(A/B/C)are edited by the international board of distinguished Chinese and foreign scientists,and are aimed to present the latest developments and achievements in scientific research in China and overseas to the world’s scientific circles,especially to stimulate     

SCIENCE CHINA Information Sciences SUBJECT INDEX TO VOLUME 57(2014)

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Information for Authors

正http://www.zju.edu.cn/jzus http://www.springerlink.com Aim The Journals of Zhejiang University-SCIENCE(A/B/C)are edited by the international board of distinguished Chinese and foreign scientists,and are aimed to present the latest developments and achievements in scientific research in China and overseas to the world’s scientific circles,especially to stimulate