共查询到19条相似文献,搜索用时 78 毫秒
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综述了近年来色谱-质谱联用技术在食品分析中的应用。这些应用包括气相色谱-质谱联用分析食品中农药残留、兽药残留,以及液相色谱-质谱联用法用于食品中兽药残留,违规食品添加剂、霉菌毒素等的测定。 相似文献
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朱庆华 《中国新技术新产品》2015,(6):12
随着我国经济的快速发展,对于石油的需求量也越来越多,在石油的勘测过程中使用全二维气相色谱—飞行时间质谱技术来对开采出来的石油地质样品进行了分析研究,通过使用此项技术来对原油进行分析能够直接显示原油中的组分,各种烃类物质的组成分布在特征区域,此项技术在石油勘探研究中有着非常广泛的的应用。 相似文献
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信噪比是气相色谱-质谱联用仪的一个重要参数,本文依据JJF1164-2006《台式气相色谱—质谱联用仪校准规范》,介绍台式气相色谱—质谱联用仪信噪比的不确定度评定方法。 相似文献
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建立了气相色谱-质谱联用内标法测定干性食品包装纸中N-甲基吡咯烷酮的分析方法。采用超声提取为前处理方式,使用乙醇为溶剂,目标物用GC-MS 进行了测定,内标法定量。探讨了不同萃取溶剂对目标物的提取效率,优选了合适的提取溶剂用量,比较了不同样品的提取方式及条件;甄选出合适的内标物,确定了较佳的特征离子及其丰度比,分析了色谱柱流量、进样量及分流比对目标物分离的影响,得到了合适的色谱分析条件。在优化的实验条件下,目标物N-甲基吡咯烷酮在0. 02745 ~2. 196 mg/ L 范围内具有良好的线性关系,相关系数(R2 )为0. 9999,平均回收率为98. 36 % ~ 108. 29 %,相对标准偏差为3. 71% ~ 6. 05 %,检出限为0. 058mg/ kg,定量下限为0. 194 mg/ kg。该方法简便、快速、灵敏、准确,适合于干性食品包装纸中N-甲基吡咯烷酮的测定。 相似文献
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The interfacing of capillary column supercritical fluid chromatography (SFC) to time-of-flight mass spectrometry (TOFMS) through atmospheric pressure chemical ionization (APCI) was investigated. An ion source chamber and a new, flexible, and efficient transfer line from the SFC to the TOFMS system were designed to accommodate the requirements of this study. Ionization of analytes was performed using a corona discharge needle. The interface was equipped with two multiple-axis translation stages for positioning of the transfer line tip and the discharge needle inside the ion chamber. The investigations were oriented toward the optimization of parameters which have a strong effect on the intensity and stability of the analyte signal, including background stability, corona discharge needle positioning in the ion source, transfer line tip and discharge needle relative positioning, curtain gas and makeup gas flow interactions, ion chamber temperature, and elution pressure of analytes from the SFC system. 相似文献
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Hyphenation of liquid chromatography (LC) techniques with electrospray ionization (ESI) orthogonal acceleration time-of-flight (oa-TOF) mass spectrometry (MS) provides both MS-based structural information and LC-based quantitative data in polymer analysis. In one experimental setup, three different LC modes are interfaced with MS: size-exclusion chromatography (SEC/MS), gradient polymer elution chromatography (GPEC/MS), and liquid chromatography at the critical point of adsorption (LCCC/MS). In SEC/MS, both absolute mass calibration of the SEC column based on the polymer itself and determination of monomers and end groups from the mass spectra are achieved. GPEC/MS shows detailed chemical heterogeneity of the polymer and the chemical composition distribution within oligomer groups. In LCCC/MS, the retention behavior is primarily governed by chemical heterogeneities, such as different end group functionalities, and quantitative end group calculations can be easily made. The potential of these methods and the benefit of time-of-flight analyzers in polymer analysis are discussed using SEC/MS of a polydisperse poly(methyl methacrylate) sample, GPEC/MS of dipropoxylated bisphenol A/adipic acid polyester resin, LCCC/MS of alkylated poly(ethylene glycol), and LCCC/MS of terephthalic acid/neopentyl glycol polyester resin. 相似文献
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A microfabricated microfluidic device coupled with a nanospray tip for electrospray ionization of dilute solutions is described. The device has been interfaced with a time-of-flight mass spectrometer and evaluated for sensitive, high-speed detection of peptides and proteins. The electrospray voltage was applied through the microchip to the nanospray capillary that was attached at the end of a microfabricated channel. Fluid delivery rates were 20-30 nL min(-)(1) through the hybridized structure without any pressure assistance. On-line microchip electrophoresis has been demonstrated and the effect of the capillary-chip junction on band broadening examined. Full mass spectra are acquired within 10-20 ms at 50-100 spectra s(-)(1) storage rates. Detection of subattomole levels of sample from a 100 nM solution is demonstrated for infusion experiments. 相似文献
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The pulsed glow discharge (GD) plasma source exhibits several characteristics that make it ideally suited for use with time-of-flight mass spectrometry (TOFMS). TOFMS uniquely affords the ability to monitor a narrow temporal window for a time-varying process such as ion formation in the pulsed glow discharge plasma. Pulsed GD-TOFMS exhibited distinct advantages for the direct determination of trace elements in solid state samples. Initially, the pulse-powered GD-TOFMS system used for these investigations exhibited poor resolution. In an effort to improve resolution, a slit was introduced to narrow the ion beam orthogonally entering the extraction region of the TOFMS. In an effort to determine optimal operating conditions, the influence of slit width on TOF performance was investigated. In the course of this study, the slit width was found to influence isotope ratio accuracy as well as resolution. A slit width of 1.0 mm was determined to provide the best compromise between resolution and isotope ratio accuracy. Pulsed GD-TOFMS affords improved sensitivity and selectivity because Penning ionization is enhanced during the time period immediately following the termination of the discharge power. Ions sampled by an extraction pulse applied after power termination also yield a mass spectrum that is free of contributions arising from electron-ionized interferences. This advantage arises because only ions generated via the Penning ionization mechanism persist after the termination of discharge power. Sampling in the "afterpeak" time regime eliminates the saturation of the detector arising from discharge support gas ion signal. 相似文献
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猪肉中二溴磷残留量的气相色谱和气相色谱/质谱分析 总被引:1,自引:0,他引:1
试样经盐酸酸化,用正己烷提取残留的二溴磷。提取液在-20℃冷冻2小时凝固析出脂肪,净化液经浓缩定容后,用配有电子俘获检测器的气相色谱测定(GC-ECD),外标定量,并用气相色谱—质谱(选择离子监测)(GC/MS(SIM))进行确证。以HP-5大口径毛细管柱和HP-5MS毛细管柱为分离柱,选择出合适的色谱条件,二溴磷的分离效果良好。本方法对猪肉样品的测定低限为0.05mg/kg;添加浓度为0.05mg/kg~1.00mg/kg时,回收率为89%以上;相对标准偏差小于5.0%;标准进样量在0.1~10.0ng范围内,线性关系良好,r=0.9995。样品前处理采用了微量化学法(MiccM)技术,质谱(选择离子监测)确证的监测离子选m/z 301、185、109amu。 相似文献
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粮谷中嗪草酮残留量的气相色谱和气相色谱-质谱分析 总被引:1,自引:0,他引:1
粮谷中嗪草酮残留用苯提取,提取液经浓缩、定容后直接用配有氮磷检测器的气相色谱仪测定,并用气相色谱-质谱(选择离子监测)进行确证。以HP-1大口径毛细管柱和HP-1毛细管柱为分离柱,选择出合适的色谱条件,嗪草酮的分离效果良好。本方法对大米样品的测定下限为0.05mg/kg;添加浓度为0.05mg/kg~1.0mg/kg的嗪草酮,回收率为80%以上;相对标准偏差小于9.5%。样品前处理采用了微量化学法(MiccM)技术,质谱(选择离子监测)确证的监测离子选M/Z103、144、182、198、214amu。 相似文献
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The laser desorption/laser ionization time-of-flight (L2ToF), mass spectra of anthracene and the anthracene-picric acid charge transfer (C-T) complex have been compared at a desorption and ionization wavelength of 266 nm. Laser desorption/ionization spectra of anthracene were obtained at low temperatures (-30 °C) to minimize the interference from gas phase ionization. Positive ion mass spectra of the picrate C-T complex at room temperature comprise the parent ion of anthracene and were devoid of signals associated with the picric acid component. The L2ToF analyses of a mixture of volatile and involatile EPA priority PAHs in picric acid show that low molecular weight PAHs form involatile charge transfer complexes. The present method reduces the possibility of volatile PAH loss during mass spectrometric analyses in vacuo. 相似文献
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A method has been developed for the analysis of carbendazim in agricultural samples. This has been accomplished by the combination of laser desorption with resonance-enhanced multi-photon ionization (REMPI) coupled to time-of-flight mass spectrometry detection. After the optimization of the experimental conditions and the location of the resonant wavelength of the substance, several samples of pepper extract enriched with carbendazim were analyzed, finding a detection limit of the same order of magnitude as that of current GC and HPLC techniques, but with higher sensitivity and faster sample preparation. 相似文献