食品运载体系提高酚类物质生物利用度的研究进展

酚类物质已被证实具有降低冠心病、糖尿病、癌症和其他慢性疾病患病率的功能,近年来,如何将其作为生物活性物质应用到在食品和药品领域受到广泛关注。然而酚类物质的低水溶性、低稳定性、被动扩散方式以及在胃肠道环境中的损失限制了其在人体内的生物利用度。目前解除这些限制的最佳方法就是基于食品运载体封装技术对酚类物质进行包埋,这种方法已被证实可有效提高活性成分的稳定性和生物利用度。本文介绍了酚类物质的功能性质和评价其生物利用度的常见方法,对现有的运载体系及其在提高酚类物质生物利用度方面的应用现状进行综述,最后针对目前研究中存在的问题对未来酚类物质运载体系的研究方向提出合理建议。     

白藜芦醇的生物活性及其运载体系研究进展

白藜芦醇是一种主要存在于葡萄、花生、虎杖等植物中的天然多酚,具有抗氧化、抗菌消炎、抗心血管疾病、抗肿瘤等多种生物活性,在食品、药品及日化品领域都有广泛应用。但由于白藜芦醇性质不稳定、水溶性差等特点,限制了其应用范围,因此,利用运载体系提高其生物利用度是一个关键的研究方向。本文总结了白藜芦醇理化性质及生物活性,并对近年来有关白藜芦醇的运载体系进行综述,提出现有运载体系存在的问题,以期为白藜芦醇的运载体系的发展提供参考。     

白酒中酚类物质及检测方法的研究进展

酚类物质是白酒的风味物质,对白酒的香气、口感和稳定性均起到重要作用。同时其具有多种生物活性,为适量饮酒有益健康提供了依据。对白酒中酚类物质的风味特征、来源、生理活性、检测方法及酒体中组成和含量进行综述,为研究白酒中酚类物质提供参考。     

植物食品原料中酚酸的生物合成与调控及其生物活性研究进展

酚酸是高等植物中广泛分布的含有酚羟基和羧基的一类次生代谢产物,主要通过酯键及醚键与细胞壁结构 组分以结合态存在于植物食品原料中,具有抗氧化、抗菌和抗癌等多种生物活性。植物食品原料中的酚类物质已成 为当前食品领域研究热点之一。通过一系列生物调控技术能够在植物食品原料中富集酚酸,从而提高其营养价值。 本文综述了植物食品原料中酚酸的类型与结构、生物合成与调控及其生物活性,并对此进行了展望。     

食品运载体系包埋叶黄素的研究进展

叶黄素属于类胡萝卜素,具有多种生物活性功能,可以避免视网膜色素上皮细胞受蓝光损伤、预防心脑血管疾病、抗肿瘤等;此外,叶黄素还是天然的食品着色剂和抗氧化剂。但是叶黄素存在水溶性和化学稳定性较差、生物利用率低等缺陷,这限制了其在食品领域中的应用。利用食品运载体系可以解决上述问题。本文分析了限制叶黄素应用的原因,对现有食品运载体系包埋叶黄素的研究现状进行综述,以期为叶黄素的进一步研究与应用提供参考。     

食品运载体系包埋叶黄素的研究进展

叶黄素属于类胡萝卜素,具有多种生物活性功能,可以避免视网膜色素上皮细胞受蓝光损伤、预防心脑血管疾病、抗肿瘤等;此外,叶黄素还是天然的食品着色剂和抗氧化剂。但是叶黄素存在水溶性和化学稳定性较差、生物利用率低等缺陷,这限制了其在食品领域中的应用。利用食品运载体系可以解决上述问题。本文分析了限制叶黄素应用的原因,对现有食品运载体系包埋叶黄素的研究现状进行综述,以期为叶黄素的进一步研究与应用提供参考。     

苹果渣中多酚类物质的提取和应用研究进展

苹果多酚是苹果中多元酚类物质的总称,具有良好的保健和药理功能。本文主要论述了苹果渣中多酚类物质的组分、性质、生物活性以及干苹果渣中提取、纯化多酚类物质的研究及应用现状。     

枇杷酚类物质及其生物活性研究进展

枇杷富含酚类物质,目前已鉴定酚酸(羟基肉桂酸和羟基苯甲酸)和黄酮类(黄酮醇、黄烷酮、黄烷醇和黄酮木脂素)等物质50余种。不同组织、品种、发育阶段和采后处理方法均能影响酚类物质组成和含量。枇杷酚类物质有抗氧化、消炎、抗糖尿病、细胞保护、抑菌等生物活性。本文对枇杷酚类物质组成、含量分布和生物活性进行综述。     

消化过程中多酚类物质的稳定性研究进展

多酚类物质是存在于植物体内的次级代谢产物,因其有多种生物活性而被国内外广泛关注。基于对多酚类物质在消化过程中稳定性变化研究,将不同的酚类物质在胃肠道中的吸收情况以及影响酚类物质含量的因素进行总结,为多酚类物质在食品工业中的开发利用提供参考。     

姜黄素膜运载体系的构建及功能性应用研究进展

姜黄素因具有多种生物活性而获得广泛的研究关注,但由于其低水溶性和生理转运过程中的生化/结构降解,导致其生物利用度低下,制约其经济价值。因此,大量以姜黄素为基础的药物递送系统被引入,其中,将姜黄素纳入以生物聚合物为基础的膜运载体系被认为具有广阔的发展前景。多糖、蛋白质等都是经过广泛研究的聚合物载体,能够用于输送多种生物活性天然化合物。本文对姜黄素分子递送过程中存在的挑战以及构建姜黄素膜运载体系的研究进展进行概述,着重阐述姜黄素膜运载体系在食品抗氧化包装、新鲜度监测以及抗菌保鲜等方面的应用,旨在为姜黄素的进一步开发与应用提供理论参考。     

Biopolymer nanoparticles: a strategy to enhance stability,bioavailability, and biological effects of phenolic compounds as functional ingredients

Phenolic compounds are abundant in nature and have multiple beneficial effects on human health due to their antioxidant, anti-inflammatory, antithrombotic, antiallergenic, anticancer, and antiatherosclerotic properties. For this reason, phenolics are becoming relevant functional ingredients for several industries, mainly the food industry, derived from food consumer exigencies and regulations. However, the use of their beneficial properties still presents some limitations, such as chemical instability under environmental and processing conditions, which leads to structural changes and compromises their biological activities. They also present poor water solubility and sensitivity to pH changes, decreasing their bioavailability in the organism. The technologies for extraction and stabilization of these compounds have evolved rapidly in the development of different delivery systems to encapsulate sensitive active molecules. Biopolymeric nanoparticles are biodegradable polymer-based colloidal systems with sizes ranging from 1 to 1000 nm, and different techniques can be carried out to develop them. These systems have emerged as a green and effective alternative to improve stability, bioavailability, and biological effects of phenolic compounds. This comprehensive review aims to present an overview of recent advances in encapsulation processes of phenolic compounds within biopolymer nanoparticles as delivery systems and the impact on their physicochemical properties and biological effects after encapsulation. © 2021 Society of Chemical Industry.     

Solid lipid nanoparticles as oral delivery systems of phenolic compounds: Overcoming pharmacokinetic limitations for nutraceutical applications

Drug delivery systems, accompanied by nanoparticle technology, have recently emerged as prominent solutions to improve the pharmacokinetic properties, namely bioavailability, of therapeutic and nutraceutical agents. Solid lipid nanoparticles (SLNs) have received much attention from researchers due to their potential to protect or improve drug properties. SLNs have been reported to be an alternative system to traditional carriers, such as emulsions, liposomes, and polymeric nanoparticles. Phenolic compounds are widespread in plant-derived foodstuffs and therefore abundant in our diet. Over the last decades, phenolic compounds have received considerable attention due to several health promoting properties, mostly related to their antioxidant activity, which can have important implications for health. However, most of these compounds have been associated with poor bioavailability being poorly absorbed, rapidly metabolized and eliminated, which compromises its biological and pharmacological benefits. This paper provides a systematic review of the use of SLNs as oral delivery systems of phenolic compounds, in order to overcome pharmacokinetic limitations of these compounds and improved nutraceutical potential. In vitro studies, as well as works describing topical and oral treatments will be revisited and discussed. The classification, synthesis, and clinical application of these nanomaterials will be also considered in this review article.     

Interactions between proteins and phenolics: effects of food processing on the content and digestibility of phenolic compounds

Phenolic compounds have recently become one of the most interesting topics in different research areas, especially in food science and nutrition due to their health-promoting effects. Phenolic compounds are found together with macronutrients and micronutrients in foods and within several food systems. The coexistence of phenolics and other food components can lead to their interaction resulting in complex formation. This review article aims to cover the effects of thermal and non-thermal processing techniques on the protein–phenolic interaction especially focusing on the content and digestibility of phenolics by discussing recently published research articles. It is clear that the processing conditions and individual properties of phenolics and proteins are the most effective factors in the final content and intestinal fates of phenolic compounds. Besides, thermal and non-thermal treatments, such as high-pressure processing, pulsed electric field, cold plasma, ultrasonication, and fermentation may induce alterations  in those interactions. Still, new investigations are required for different food processing treatments by using a wide range of food products to enlighten new functional and healthier food product design, to provide the optimized processing conditions of foods for obtaining better quality, higher nutritional properties, and health benefits. © 2024 Society of Chemical Industry.     

天然酚类化合物的抑菌作用及在肉与肉制品中的应用研究进展

氧化和微生物腐败是影响肉与肉制品品质和货架期的主要原因。从植物中提取的酚类化合物具有抗氧化和抑菌活性,但其抑菌机制尚不完全明确,同时缺乏较为系统、深入的总结。本文基于天然酚类化合物的分类和抑菌活性差异,从细胞壁、细胞膜、生物膜和蛋白质的合成等方面分析总结酚类化合物可能的抑菌机制及其在肉类工业中的应用情况,以期为研究天然酚类化合物的抑菌机制及其在肉类生产加工中的应用提供理论基础。     

Occurrence,types, properties and interactions of phenolic compounds with other food constituents in oil-bearing plants

ABSTRACT

Phenolic phytochemicals have become of interest due to their therapeutic potential, particularly with regards to their anti-cancer, anti-inflammatory, hypolipidemic, and hypoglycemic properties. An evolving area of research involving phenolics in foods and their products pertains to the functional, biological, and nutritional consequences resulting from the binding between certain phenolic compounds and the macronutrient and micronutrient constituents of foods. The goal of this review is to provide a summary of studies investigating endogenous phenolic interactions with major components in food systems, including carbohydrates, proteins, lipids, minerals and vitamins, with a focus on the phenolic compounds and nutrients in oil-bearing plants. Another major objective is to provide a comprehensive overview of the chemical nature of phenolic interactions with food constituents that could affect the quality, nutritional and functional properties of foods. Such information can assist in the discovery and optimization of specific phenolic complexes in plant-based foods that could be utilized towards various applications in the food, nutraceutical and pharmaceutical industries.     

The phenolic composition and antioxidant capacity of soluble and bound extracts in selected dietary spices and medicinal herbs

Phenolic compounds, commonly found in plant‐based foods, exist in free or bound form. Despite much research on the soluble phenolics in spices and herbs, their bound phenolics have not been intensively investigated. In this study, six common dietary spices and medicinal herbs (Padang cassia, oregano, clove, Chinese cassia, Japanese knotweed and peel of pomegranate) were selected to evaluate and compare their phenolic composition and antioxidant capacity in soluble extracts (SEs) and bound extracts (BEs). Generally, the samples had high total phenolic content and antioxidant capacity, with lower levels in the BEs. From the HPLC results, (+)‐catechin, (?)‐epicatechin, eugenol, cinnamaldehyde and carvacrol were the major phenolic compounds in the SEs, and gallic acid, p‐coumaric acid and ellagic acid in the BEs. Phenolic compounds are likely the major contributors to the antioxidant capacity of these plant samples. Overall, these dietary spices and medicinal herbs can be excellent sources of natural antioxidant phenolics.     

葡萄酒酚类物质研究进展

酚类物质作为葡萄酒的“骨架成分”,在葡萄酒中起着重要作用,不仅影响葡萄酒的颜色、滋味和口味等,还具有抗氧化作用。概述了葡萄酒中主要的酚类物质及其作用研究进展。     

全谷物酚类化合物抗氧化活性研究进展

全谷物中含有多种生物活性成分,如酚类化合物、β-葡聚糖、膳食纤维等,其中,酚类化合物以其独特的抗氧化功能而备受人们的青睐。本文综述全谷物酚类化合物的组成、存在形式、影响其含量的因素及其抗氧化效果的评价方法,旨为全谷物酚类化合物的研究提供参考。     

水产品中常见酚类化合物检测方法研究进展

作为当前被广泛关注的水体污染物之一,酚类化合物分布广泛、种类繁多、危害性高。酚类化合物不仅可通过生活饮用水直接进入人体,也可经水体及水体微生物转移到水产品中,在水产品中富集,并通过食物链对人体造成潜在的危害,因此对水产品中酚类化合物的研究具有极其重要的意义。本研究综合调研了水产品中常见酚类化合物的研究现状,重点聚焦了常见酚类化合物相关检测技术进展,以期探寻便捷、高效、灵敏的酚类化合物检测技术,为研究和制定水产品中酚类化合物检测方法标准提供依据。