雷美替胺的合成路线改进

以1,2,6,7-四氢-8H-茚并[5,4-b]呋喃-8-酮为原料,经缩合、氢化两步得到外消旋中间体。再通过N-乙酰基-L-苯丙氨酸拆分获得S-型异构体中间体,最后通过丙酰氯试剂酰化生成雷美替胺原料药。改进后的工艺操作简便,条件温和,中间体和产物反应终点易于监控,总收率为13%,适合工业化生产。     

集成道路上SoC与SiP谁主浮沉？

与昌圆双雄(台积电、联电)有着密不可分的IC设计服务公司创意与智原,于2003年8、9月接二连三的成立IP Mall,其希望透过IP(Intellectual Property)交易平台的建立,授权给IC设计业者加速重复使用IP以缩短芯片开发时间,也迫使SoC(System-on-a-Chip)与SiP(System-in-a-Package)的争夺战再一次浮上台面。     

马建民追求卓越

人在一生中能有几个顿悟的时刻?豁然开朗、茅塞顿开，仿佛冥冥中神灵的仙指点化，为人生与事业的苦旅指明一条阳光大道。这样的时刻并不多得，因为大多数人不愿忍受顿悟之前求索的忧烦苦闷。三年前，作着一个普普通通、优哉游哉的小书商的马建民，忽然发现了自己未来要走的路。     

QUANTUM MECHANICAL MODEL AND SIMULATION OF GaAs/AlGaAs QUANTUM WELL INFRARED PHOTO- DETECTOR-Ⅰ OPTICAL ASPECTS

ＩｎｔｒｏｄｕｃｔｉｏｎＩｎｆｒａｒｅｄｄｅｔｅｃｔｏｒｔｅｃｈｎｉｑｕｅｈａｓｂｅｅｎａｋｅｙｆａｃｔｏｒｉｎｔｈｅｄｅｖｅｌｏｐｍｅｎｔｏｆｔｈｅｉｎｆｒａｒｅｄｔｅｃｈｎｏｌｏｇｙｆｏｒｍｏｒｅｔｈａｎ 4 0 ｙｅａｒｓ .Ｓｉｎｃｅ 1970 ,ｓｅｍｉｃｏｎｄｕｃｔｏｒｓｌｉｋｅＩｎＳｂａｎｄＨｇＣｄＴｅｈａｖｅｂｅｅｎｔｈｅｐｒｉｎｃｉｐａｌｍａｔｅｒｉａｌｓｆｏｒｖａｒｉｏｕｓｉｎｆｒａｒｅｄｄｅｔｅｃｔｏｒａｐｐｌｉｃａｔｉｏｎｓ .Ｔｈｅｆｏｒｍａｔｏｆｔｈｅｉｎｆｒａｒｅｄｄｅｔｅｃｔｏｒｍｏｔｉｖａｔｅｄｂｙｓｍａｒｔｔｈｅｒｍａｌｉｍａｇｉｎｇｓｙｓｔｅｍｃｈａｎｇｅｄｆｒｏｍｓｉｎｇｌｅｅｌｅｍｅｎｔｄｅｖｉｃｅｔｏｆｏｃａｌｐｌａｎａｒｒａｙｓ(ＦＰＡｓ)ｉｎｔｈｅｍｉｄｄｌｅｏｆ 80’ｓ [1].Ｔｏｄａｙ’ｓｔｅｃｈｎｏｌｏｇｙｏｆｉｎｆｒａｒｅｄｄｅｔｅｃｔｏｒｃｏｎｃｅｎｔｒａｔｅｓｌａｒｇｅｌｙｏｎｆｏｃａｌｐｌａｎａｒｒａｙｓ ,ｅｘｐｅｃｉａｌｌｙｆｏｒｓｅｎｓｉｔｉｖｅ ,ｈｏｍｏｇｅｎｅｏｕｓａｎｄｌａｒｇｅｆｏｒｍａｔｓｃａｌｅｄｅｖｉｃｅｓ .ＨｇＣｄＴｅ...     

摩托罗拉8位HC08微控制器系列

摩托罗拉微控制器(MCU)具有编程语言简单、外围设备齐全、存储器模型用户友好、选择广及供应多、性能价格比高等优点,被设计者评为最容易使用的产品之一。在全球顶级的原始设备制造厂商(OEM)的无数嵌入式系统和用户最终产品中都可找到摩托罗拉的MCU,包括键盘、传呼机、电子游戏机、洗衣机、安全系统及汽车等。     

Nucleation Mechanism for Bainite

Based on the experimental results that solute-depleted zone was observed in Cu-28Zn-4AI (mass fraction) at 523 K, AG is calculated as a positive according to the thermodynamic criteria for the spinodal decomposition of a ternary systems. So, the solute-depleted zone cannot be formed by spinodal decomposition. Dislocation density required by the formation of solute-depleted zone is estimated greater than 7.89×109 cm-2, according to the segregation of solute atoms around dislocations, which is not consistent with the practical situation for the alloy at 523 K. Associated with the internal friction experimental fact that internal friction peaks appear within the incubation for bainitic transformation in Cu-Zn-AI alloy, the equilibrium temperature, TO, is evaluated as 433 K for solute-depleted Cu-25Zn-3.4AI, which is lower than the experimental temperature 523 K. Thus, nucleation by shear mechanism is impossible in this circumstance. Therefore, it is concluded that, like bainite in steels and Ag-Cd, bainite in     

Preparation of Laminin-apatite-polymer Composites Using Metastable Calcium Phosphate Solutions

A synthetic polymer with a laminin-apatite composite layer on its surface would be useful as a percutaneous device. The preparation of such a composite was attempted in the present study using poly（ ethylene terephthalate ） （PET） and polyethylene （PE） as the synthetic polymer. PET and PE plates and those pretreated with an oxygen plasma were alternately dipped in calcium and phosphate ion solutions, and then immersed in a metastable calcium phosphate solution supplemented with laminin （ LCP solution ）. The PET and PE plates pretreated with an oxygen plasma formed a uniform and continuous layer of a laminin-apatite composite on their surfaces. In contrast, the PET and PE plates that had not been pretreated with an oxygen plasma did not form a continuous layer of a laminin-apatite composite on their surfaces. The hydrophilic functional groups on the PET and PE surfaces introduced by the plasma treatment were responsible for the successful laminin-apatite coruposite coating.     

汽车漆漆膜质量的改进与提高

通过对车身漆膜质量问题的分析,采取专业清洁公司整体承包车间保洁、工艺方面改进、更换生产外材料、供应商加强对汽车漆使用的监控等一系列措施,漆膜质量水平得以提高.     

王甫洲水电厂进水口拦污栅振动观测和技术改造

通过现场考察、原型观测和有限元计算,分析了拦污栅断裂的原因,提出了技术改造的建议.