沙枣种子总酚抗氧化活性研究

目的研究沙枣种子总酚体外与体内的抗氧化活性。方法体外实验考察了沙枣总酚的还原力,对DPPH·、O_2~-和·OH的清除作用以及对·OH损伤DNA的保护作用等;体内实验中将小鼠随机分为空白组、D-半乳糖模型组(50 mg/kg)、Vc阳性对照组(50 mg/kg),沙枣总酚低(50 mg/kg)、中(100 mg/kg)、高(200 mg/kg)剂量组,灌胃给予相应药物2周后采血,幵测定血清中超氧化物歧化酶(superoxide dismutase,SOD)和丙二醛(malondialodehyde,MDA)的含量,综合分析沙枣总酚的体外和体内抗氧化活性。结果沙枣总酚有强的还原能力,对DPPH·、O_2~-和·OH的清除率分别达30.02%、25.91%和38.55%,其浓度与自由基清除活性呈现一定的量效关系;沙枣总酚对·OH引起的DNA损伤具有一定的保护作用。与模型组比较,沙枣总酚能显著提高衰老小鼠血清SOD活力(P0.01),降低血清MDA水平(P0.01)。结论综合体外和体内实验结果,沙枣总酚显示一定的抗氧化作用,有望开发为新的植物抗氧化剂。     

A conceptual definition of a holonic processing framework to support the design of information fusion systems

This paper proposes a conceptual definition of an information fusion (IF) processing framework. Several concepts borrowed from complex systems theory, informational philosophy and computer sciences have been integrated to conceptualize that framework. The concepts of holon and informon developed by Koestler, Sulis, Alonso, Paggi et al. are exploited here to develop an information fusion processing framework. The proposed functional holonic structure is suitable for processing any level of information abstraction of the Joint Directors of Laboratory (JDL) data fusion model. The framework comprises the characterization of a basic element of information and the definition of an IF cell as a basic IF system unit to achieve fusion of information. The framework advocates a goal-driven approach with notions coming from business sciences to take into account quality of information for managing the fusion process. The framework is illustrated through several examples namely with an elaborated case in remote sensing.