Confocal Blood Flow Videomicroscopy of Thrombus Formation over Human Arteries and Local Targeting of P2X7

Atherothrombosis exposes vascular components to blood. Currently, new antithrombotic therapies are emerging. Herein we investigated thrombogenesis of human arteries with/without atherosclerosis, and the interaction of coagulation and vascular components, we and explored the anti-thrombogenic efficacy of blockade of the P2X purinoceptor 7 (P2X7). A confocal blood flow videomicroscopy system was performed on cryosections of internal mammary artery (IMA) or carotid plaque (CPL) determining/localizing platelets and fibrin. Blood from healthy donors elicited thrombi over arterial layers. Confocal microscopy associated thrombus with tissue presence of collagen type I, laminin, fibrin(ogen) and tissue factor (TF). The addition of antibodies blocking TF (aTF) or factor XI (aFXI) to blood significantly reduced fibrin deposition, variable platelet aggregation and aTF + aFXI almost abolished thrombus formation, showing synergy between coagulation pathways. A scarce effect of aTF over sub-endothelial regions, more abundant in tissue TF and bundles of laminin and collagen type I than deep intima, may suggest tissue thrombogenicity as molecular structure-related. Consistently with TF-related vascular function and expression of P2X7, the sections from CPL but not IMA tissue cultures pre-treated with the P2X7 antagonist A740003 demonstrated poor thrombogenesis in flow experiments. These data hint to local targeting studies on P2X7 modulation for atherothrombosis prevention/therapy.     

Investigation into the evolution of corrosion product layer (CPL) of 1018 C-steel exposed to multiphase environment using FIB and EIS techniques

This communication reports into the effects of flow, fluid composition and the effectiveness of imidazoline inhibitors on the evolution and distribution of corrosion products on 1018 C-steel exposed to CO₂ corrosion. Focused ion beam technique was used to measure the thickness of the corrosion product layer (CPL), in contrast to the conventional techniques used to observe the cross-section of specimens. Morphological analysis using scanning electron microscopy revealed topographical variations on the surface with the change in the multiphase environment. The CPL was found to be more porous in nature with the presence of oil in the multiphase environment. Electrochemical impedance spectroscopy was also used in the present study to measure the corrosion rates and was subsequently correlated to the CPL evolution for 1018 C-steel in multiphase environment.     

基于构件复用机制的从CPL到Java的翻译系统

给出了CPL构件的复用机制,定义了一种对构件组合约束检查的矩阵技术.通过比较CPL语言与Java语言的语法特点,在XML规范的框架内,提出了一种将CPL语言翻译成等价功能的Java代码的翻译方法.该方法采用基于EJB容器的思想,并使用类对象的形式构造整个业务,用JavaBeans表示CPL中的功能构件,使翻译成的Java代码具有良好的可读性,并具有较高的可复用性及可扩展性.     

面向AS级动态拓扑的改进PFP模型

针对传统PFP模型不能很好模拟Internet动态演化的问题,提出面向自治系统(AS)级动态拓扑的改进PFP模型。改进模型充分考虑Internet中AS节点的消亡与连接边的相应连接补偿,符合Internet拓扑成长和演化过程,生成的Internet拓扑图与实际Internet具有更大相似度。实验结果表明,改进模型能较好满足幂律分布和小世界特性,更适合于Internet建模。     

小型CPL用高性能烧结毛细芯的研制

采用粉浆浇注工艺和氢气还原烧结工艺研制小型CPL用烧结镍毛细芯，通过优选粉浆液固比、添加剂的种类与数量、浆料pH值等参数制备了符合设计要求的烧结毛细芯。测试了毛细芯孔径、孔隙分布特征、孔径分布、孔隙度、渗透率等性能参数，分析了烧结气氛、温度、时间对毛细芯性能的影响。试验结果表明，研制的毛细芯孔隙度在68％以上，孔隙尺寸约4μm，渗透系数在10^-12～10^-13m^2之间。     

A mathematical model to analyze heat and mass transfer characteristics of a CPL evaporator porous wick

A capillary pumped loop (CPL), because of its high power thermal transport character, has been developed as an attractive system for the thermal discharge of electronic chips with high power loads, especially on spacecrafts. A working fluid having relatively larger heat of evaporation, methanol for example, may transfer significant heat flux. In this paper a new mathematic model is constructed, in which the most important character is the treatment or the unsaturated region of the evaporator porous wick. Numerical simulation of heat and mass transfer in the evaporator porous wick is carried out with a new three‐layer model. The importance of unsaturated layer to simulate the present problem is clear. © 2005 Wiley Periodicals, Inc. Heat Trans Asian Res, 34(4): 209–218, 2005; Published online in Wiley InterScience ( www.interscience.wiley.com ). DOI 10.1002/htj.20066     

Nylon—6含油废水除油并回收单体的实验研究

本文介绍了Ｎｙｌｏｎ－６含油乳化废水破乳除油并回收单体的方法。     

Circular Dichroism and Circular Polarized Luminescence from a Green Fluorescent Protein—Initial Research for Chiroptical Emission of Biological Materials

Optical properties of a green fluorescent protein (GFP) are examined using optical absorption, circular dichroism (CD), and circular polarized luminescence (CPL) spectroscopies. The GFP has chiroptical activity and exhibits green circular polarized emission, although the g _em-factor is small. Poly(vinyl alcohol) (PVA)/GFP composite films are prepared to attempt long-term preservation of the GFP emission activity. After five years, the transparent PVA/GFP composite film still exhibits stable fluorescence that appears similar to the emission from the Aequorea jellyfish.     

基于SIP的多媒体通信的个性化服务

本文主要描述了SIP（Session Initiation Protocal）实现多媒体通信的三层框架，重点介绍了CPL（Call Processing Language）和SCML（Service Control Markup Language）所能实现的扩展服务，并创造性地将各种个性化服务集成到同一系统中以供用户订制选择，从而对比得出SCML与CPL的特性与适用范围。     

己内酰胺行业发展设想

通过对我国己内酰胺行业供需和技术现状的剖析，结合己内酰胺行业特点和我国己内酰胺行业存在的问题，提出己内酰胺行业发展战略的观点和思路。