KJS-Y系列矿用水动力降尘器的改进设计

针对当前KJS-Y系列降尘器效率低的问题,通过调整叶轮轴向间隙与径向间隙参数,分别对不同安装参数的降尘器进行数值模拟,通过数值模拟分析特定截面压力分布情况,确定了叶轮最佳安装参数,大大提高了降尘器的工作效率,同时降低了设计成本。     

The Critical Role of Passive Permeability in Designing Successful Drugs

Passive permeability is a key property in drug disposition and delivery. It is critical for gastrointestinal absorption, brain penetration, renal reabsorption, defining clearance mechanisms and drug-drug interactions. Passive diffusion rate is translatable across tissues and animal species, while the extent of absorption is dependent on drug properties, as well as in vivo physiology/pathophysiology. Design principles have been developed to guide medicinal chemistry to enhance absorption, which combine the balance of aqueous solubility, permeability and the sometimes unfavorable compound characteristic demanded by the target. Permeability assays have been implemented that enable rapid development of structure-permeability relationships for absorption improvement. Future advances in assay development to reduce nonspecific binding and improve mass balance will enable more accurately measurement of passive permeability. Design principles that integrate potency, selectivity, passive permeability and other ADMET properties facilitate rapid advancement of successful drug candidates to patients.     

机动武器系统的含间隙动力学研究--下篇:系统仿真

本文把中篇建立的间隙铰模型引入多体系统动力学分析中,得到了一种处理含间隙多体系统动力学问题的一般方法.应用这种方法对机动武器的发射过程进行了原理性的仿真,验证了前面建立的碰撞模型和间隙模型,并分析了间隙对导弹运动状态的影响.导弹发射过程具有变拓扑的特点,本文方法提供了一种处理这类问题的思路.     

A framework of virtual prototyping environment for the design and analysis of mechanical mechanism with clearance

Mechanical mechanisms with clearance abound in technological fields such as robotics, machine and steam turbine industry. The dynamic performance of these mechanisms in working condition can be achieved provided that the effects of the different on the mechanisms (such as mechanism dynamics, technological effects and thermal behaviour) are thoroughly understood. Virtual prototyping provides an integration of multi-domain dynamic simulation for the design and analysis process. In the current paper, a framework of virtual prototyping environment for the design and analysis of mechanical mechanism with clearance is presented. A case study with such a simulation strategy is studied for the optimum design and analysis of the technological parameter.     

论剪切质量的提高

通过对飞剪剪切长度，精度，剪刃间隙和压板机构等参数的优化，来提高钢板的剪切质量。     

火焰筒后段通道组件真空钎焊

对钣金涨型结构件--XX火焰筒后段通道组件的真空钎焊进行了研究,详细介绍了钎料预置和规范参数选择,其钎料预置采用粘带、粉、膏状镍基钎料Amdry915联合运用.实验结果表明,采用所制定的钎焊规范,钎焊出了满足要求的火焰筒,并已用于批生产.     

排气系统在注射模中的应用

介绍了排气系统在注射模中的重要性,排气系统位置的选择,排气系统的种类以及应用等     

NUMERICAL SIMULATION OF TIP-CLEARANCE FLOW IN CASCADE

1 .　ＩＮＴＲＯＤＵＣＴＩＯＮＴｉｐ ｃｌｅａｒａｎｃｅｆｌｏｗｓｏｃｃｕｒｉｎｖａｒｉｏｕｓｅｎｇｉｎｅｅｒ ｉｎｇａｐｐｌｉｃａｔｉｏｎｓｓｕｃｈａｓａｘｉａｌ ｆｌｏｗ ｐｕｍｐｓａｎｄｄｕｃｔ ｅｄｐｒｏｐｅｌｌｅｒｓ .Ｔｈｅｉｎｅｒｔｉａｌｆｏｒｃｅｓａｃｔｉｎｇｕｐｏｎｔｈｅｆｌｕｉｄｉｎｔｈｅｎａｒｒｏｗ ｇａｐｂｅｔｗｅｅｎｂｌａｄｅｔｉｐａｎｄｔｈｅｓｕｒｒｏｕｎｄｉｎｇｗａｌｌａｒｅｓｕｆｆｉｃｉｅｎｔｔｏ ｇｅｎｅｒａｔｅａｔｉｐｌｅａｋａｇｅｖｏｒｔｅｘｏｎｔｈｅｓｕｃｔｉｏｎｓ…     

连轧管机轧辊轴承的调整、维护及保养

本文介绍了应用于MPM连轧机轧辊上的四列圆锥滚子轴承的结构特性及其调整、维护、保养，旨在提高轴承的使用寿命。     

小间隙电解加工工艺探讨

简要阐明了小间隙电解加工的主要工艺及注意事项.