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41.
This study investigated arm posture and hand forces during bi-manual pushing. Nine male and eight female participants performed isometric exertions at two reach distances (0 and elbow-grip) and six different positions of the hand interface (handle), defined by the plane (longitudinal, lateral, horizontal) and orientation (0 degrees and 45 degrees). Electrogoniometer instruments were used to measure the displacements/postures of the wrist and elbow joints and the forearm, and force measuring strain gauges were used to measure the exerted hand forces (x-, y- and z-components). The results showed that ability to vary arm posture, particularly the forearm, is important during build up of force and that people tend to seek for a balance in the forces applied at the hands by exerting more in the vertical direction. Also, lateral plane handle positions permitted exertion of greater forces than longitudinal and horizontal plane positions. 相似文献
42.
Formative computer assisted assessment has become increasingly attractive in Higher Education where providing useful feedback to large numbers of students can be difficult. However, the nature of such assessments has often been limited to objective questions such as multiple-choice. This paper reports on the development and initial trialling of a more innovative, formative use of computer assisted assessment in a Higher Education context. The European funded PePCAA (Pedagogical Psychology Computer Assisted Assessment) project developed a series of scenario-based computer-delivered formative assessments of pedagogical psychology for teachers and trainee teachers, using a range of software features, including the addition of confidence measurement. The project had a two-fold aim: to provide a tool to improve understanding of pedagogical psychology and to explore the potential of more innovative techniques of computer assisted assessment to motivate students and to assess deeper learning. The combination of computer-delivered formative assessment with innovative question styles and confidence ratings is believed to be unique for pedagogical psychology. Scenarios were based on realistic classroom situations and focused on problem solving or on utilising best practice. The PePCAA Learning Assessment Circle (PLAC) provided a framework for indexing the kinds of processes required of users. In the UK, small scale trialling involved a total of 23 teacher trainees such that each assessment was attempted by about seven participants. Participants completed evaluation questionnaires after each assessment. Responses from learners indicated that the UK scenarios were generally very well received and had at least partly achieved the aim of stimulating deeper learning. Transfer of assessments between countries proved more difficult than expected. The next stage of development should be to conduct a larger pilot, thus allowing full investigation of the reliability and validity of the assessments. There is also scope for further development of the PePCAA approach and for its application in other subjects. 相似文献
43.
Jeanne Volatron Florent Carn Jelena Kolosnjaj‐Tabi Yasir Javed Quoc Lam Vuong Yves Gossuin Christine Ménager Nathalie Luciani Gaëlle Charron Miryana Hémadi Damien Alloyeau Florence Gazeau 《Small (Weinheim an der Bergstrasse, Germany)》2017,13(2)
Proteins implicated in iron homeostasis are assumed to be also involved in the cellular processing of iron oxide nanoparticles. In this work, the role of an endogenous iron storage protein—namely the ferritin—is examined in the remediation and biodegradation of magnetic iron oxide nanoparticles. Previous in vivo studies suggest the intracellular transfer of the iron ions released during the degradation of nanoparticles to endogenous protein cages within lysosomal compartments. Here, the capacity of ferritin cages to accommodate and store the degradation products of nanoparticles is investigated in vitro in the physiological acidic environment of the lysosomes. Moreover, it is questioned whether ferritin proteins can play an active role in the degradation of the nanoparticles. The magnetic, colloidal, and structural follow‐up of iron oxide nanoparticles and proteins in lysosome‐like medium confirms the efficient remediation of potentially harmful iron ions generated by nanoparticles within ferritins. The presence of ferritins, however, delays the degradation of particles due to a complex colloidal behavior of the mixture in acidic medium. This study exemplifies the important implications of intracellular proteins in processes of degradation and metabolization of iron oxide nanoparticles. 相似文献
44.
Tissue Engineering: Effective Light Directed Assembly of Building Blocks with Microscale Control (Small 24/2017) 下载免费PDF全文
45.
46.
Researchers on organisational ambidexterity have proposed several solutions to address the potential conflicts between exploration activities and exploitation activities. Unlike simultaneous ambidexterity, sequential ambidexterity – defined as temporal switching between exploration and exploitation – has not been examined fully, and the conditions under which this temporal switching can be successful are unclear. This paper proposes the concept of temporal switching capability to better understand the process by which sequential ambidexterity is executed. In addition, we hypothesise that performance effects are contingent upon firm-specific factors: a firm’s business strategy and absorptive capacity. Utilising three sources of data – a secondary database, annual reports and a survey administered to 145 firms in the electronics industry with 10-year observations – we find support for our hypotheses. The results show that the temporal switching capability positively relates to new product performance and that business strategy type and absorptive capacity have moderating effects. The results are meaningful in both theory and practice. 相似文献
47.
The emergence of the Internet as a global communication infrastructure has dramatically reduced interaction costs within and across organizations, with significant impact on inter-organizational relationships, vertical industry structures, and markets. More recently, service-oriented architectures (SOA) and Web services have introduced the next paradigm shift and foster the idea of dynamic business networks with quick connect and disconnect relationships. However, little research has systematically analyzed how companies leverage SOA to improve their inter-organizational relationships and reshape their business networks. In addition, the mature research stream on inter-organizational information systems (IOS) has not yet sufficiently considered SOA. In order to close this gap, our research seeks to improve the fundamental understanding of how SOA is applied in business networks and how it differs from prior forms of IOS. Using an exploratory research approach, we investigate 33 SOA cases to identify focus areas and patterns of SOA adoption in business networks. Our case analysis builds on a multi-dimensional classification scheme which we derived from prior literature. While our empirical findings do not confirm all promising propositions related to SOA, they underline the specific contribution of SOA compared to prior forms of IOS. We conclude by suggesting five clusters of SOA adoption in the inter-organizational domain, each of those introducing new aspects in the coordination of distributed business networks. 相似文献
48.
The subgraph isomorphism problem consists in deciding if there exists a copy of a pattern graph in a target graph. We introduce
in this paper a global constraint and an associated filtering algorithm to solve this problem within the context of constraint
programming. The main idea of the filtering algorithm is to label every node with respect to its relationships with other
nodes of the graph, and to define a partial order on these labels in order to express compatibility of labels for subgraph
isomorphism. This partial order over labels is used to filter domains. Labelings can also be strengthened by adding information
from the labels of neighbors. Such a strengthening can be applied iteratively until a fixpoint is reached. Practical experiments
illustrate that our new filtering approach is more effective on difficult instances of scale free graphs than state-of-the-art
algorithms and other constraint programming approaches. 相似文献
49.
Qing Zhou Christine W. Chan Paitoon Tontiwachwuthikul 《Expert systems with applications》2011,38(7):7935-7946
Amine-based carbon dioxide capture has been widely considered as a feasible ideal technology for reducing large-scale CO2 emissions and mitigating global warming. The operation of amine-based CO2 capture is a complicated task, which involves monitoring over 100 process parameters and careful manipulation of numerous valves and pumps. The current research in the field of CO2 capture has emphasized the need for improving CO2 capture efficiency and enhancing plant performance. In the present study, artificial intelligence techniques were applied for developing a knowledge-based expert system that aims at effectively monitoring and controlling the CO2 capture process and thereby enhancing CO2 capture efficiency. In developing the system, the inferential modeling technique (IMT) was applied to analyze the domain knowledge and problem-solving techniques, and a knowledge base was developed on DeltaV Simulate.The expert system helps to enhance CO2 capture system performance and efficiency by reducing the time required for diagnosis and problem solving if abnormal conditions occur. The expert system can be used as a decision-support tool that helps inexperienced operators control the plant; it can be used also for training novice operators. 相似文献
50.
Ting WangAuthor Vitae Christine ChevallereauAuthor Vitae 《Robotics and Autonomous Systems》2011,59(6):444-456
This paper presents two walking controllers for a planar biped robot with unactuated point feet. The control is based on the tracking of reference motions expressed as a function of time. First, the reference motions are adapted at each step in order to create a hybrid zero dynamic (HZD) system. Next, the stability of the walking gait under closed-loop control is evaluated with the linearization of the restricted Poincaré map of the HZD. When the controlled outputs are selected to be the actuated coordinates, most periodic walking gaits for this robot are unstable, that is, the eigenvalues of the linearized Poincaré map (ELPM) is larger than one. Therefore, two control strategies are explored to produce stable walking. The first strategy uses an event-based feedback controller to modify the ELPM and the second one is based on the choice of controlled outputs. The stability analysis show that, for the same robot and for the same reference trajectory, the stability of the walking (or ELPM) can be modified by some pertinent choices of controlled outputs. Moreover, by studying some walking characteristics of many stable cases, a necessary condition for stable walking is proposed. It is that the height of swing foot is nearly zero at the desired moment of impact. Based on this condition, the duration of the step is almost constant in presence of initial error, so a method for choosing controlled outputs for the second controller is given. By using this method, two stable domains for the controlled outputs selection are obtained. 相似文献