Lymphoma presenting as an intramuscular mass

BACKGROUND: Resection of an intramuscular mass without tissue diagnosis can lead to unnecessary surgery. METHOD: During a 4.5-year period 19 previously healthy patients referred with an undiagnosed soft tissue tumour were found to have intramuscular non-Hodgkin's lymphoma. In seven patients this was the only focus of disease (Stage IE). Patients were treated with chemotherapy or radiotherapy alone or in combination. RESULTS: After mean follow-up of 43 months all of the patients with stage IE lymphoma are alive and disease free. CONCLUSION: Primary intramuscular non-Hodgkin's lymphoma has a good prognosis. The importance of a tissue diagnosis by needle core biopsy is emphasized.     

天钢高线厂加热炉控制系统的升级改造

介绍了天钢高线厂采用SIEMENS公司SIMATIC WINCC、S7-300监控系统代替L&N公司的MICROMAXII系统对加热炉进行控制,解决了由于L&N公司倒闭而带来的备件问题。目前系统运行良好。     

Development of a dairy-based exopolysaccharide bioingredient

An exopolysaccharide (EPS)-producing Streptococcus thermophilus was used to develop an “all-dairy” ingredient with increased EPS content and greater functionality for dairy applications such as Mozzarella cheese. In laboratory-scale trials, milk protein hydrolysate (MPH), whey protein isolate (WPI) and whey protein hydrolysate (WPH) in reconstituted low-heat skim milk powder (LHSMP) were examined as additional dairy protein sources to increase the production of EPS. WPH supplementation resulted in the greatest EPS production. In batch fermentation, a medium based on LHSMP and WPH, combined with optimum conditions of temperature and pH, was used to obtain maximum production of EPS from S. thermophilus. EPS production was growth associated. The fermented biomass was harvested at the end of the exponential phase and freeze-dried. The reduced viable cell count and the retention of ropiness of the powder from the drying process enabled a higher level of EPS inoculation in a preliminary Mozzarella cheese manufacturing trial.     

Three-Dimensional Visualization of Transgenic Tobacco Leaves

We have done a three-dimensional visualization of transgenic tobacco (Nicotiana tabacum) leaves for the study of chloroplast gene expression and regulation. The aim was to visualize tobacco leaves shot with tungsten particles. These tungsten particles were coated with the foreign DNA and shot into the leaf using the biolistic technique of DNA insertion. The visualization can be used to examine the leaves to gauge the efficiency of the shooting process, i.e.,to see what parts of the leaves have been effectively penetrated by the DNA-coated tungsten particles and also to judge the depth of penetration. The image data for the 3D visualization was collected at planes 10 microns apart, using a prototype version of a High Numerical Aperture Reflecting Microscope. The raw image data collected from the microscope was restored using the Row Action Projection (RAP) algorithm and the Partial Minimization and Constrained Iteration (PCMI) algorithm. These restored images were then used for 3D visualization using the Visualization Toolkit.     

An excimer-pumped β-BaB2O4 opticalparametric oscillator tunable from 354 nm to 2.370 μm

A pulsed singly resonant optical parametric oscillator (OPO) has been constructed which can provide tunable coherent radiation over the entire wavelength range extending from 354 nm in the near ultraviolet, throughout the visible, to 2.370 μm in the near infrared using a single β-BaB₂O₄ crystal. The oscillator is pumped at 308 nm by a pulsed narrow band injection-seeded XeCl excimer laser in a near-field pumping configuration, and energy conversion efficiencies (optical-to-optical) in excess of 10% have been obtained in a 12-nm-long crystal across the OPO tuning range. The requirements placed upon the spectral and spatial coherence of the pump laser for optimum OPO operation are discussed. Experimental results on several oscillator parameters, including tuning range, oscillation threshold, energy conversion efficiency, and spatial and temporal characteristics, are presented     

Monoclonal antibody for the demonstration by ELISA of antibodies to protein p24 of enzootic bovine leukosis virus in individual and pooled blood serum and milk samples

A sensitive and specific ELISA for the demonstration of antibodies to the protein p24 of enzootic bovine leukosis virus (EBVL) using a 'capture' monoclonal antibody to this protein (MAb p24) was developed. The method is sensitive enough to detect the international reference serum E4/10 in pooled blood serum samples collected from up to 50 cows, or, if a 10-fold concentrate of milk whey is tested, in samples of bulk milk collected from up to 400 cows. The application of MAb p24 has considerably increased not only the sensitivity, but also the specificity of ELISA. Moreover it is possible to differentiate reliably between positive and 'false positive' reagents by testing a suspicious sample in a pair of wells of which one is coated with MAb p24 alone and the other with the complex MAb p24 + EBLV antigen and the subsequent calculation of 'specific absorbance'. This method, showing the highest sensitivity of detection of antibodies to EBLV p24 described so far, can become an effective tool on the sanitation of infected herds as well as in checks of the EBL-free status. A diagnostic kit suitable for commercial manufacture has been devised.     

Housing and Health Inequalities: Review and Prospects for Research

To date, relatively little research has systematically investigated relationships and pathways between housing, socio-economic status, and health status. At the same time, there is a growing awareness that one of the most important research needs in health inequalities scholarship is to better elucidate those pathways by which differences in socio-economic status manifest in everyday life, and produce, at the aggregate level, the systematic social gradient in health observed in all industrialised countries of the world. Existing 'population health' research on health inequalities provides evidence of the influence of four key factors upon health: social support, workplace organisation, income inequalities, and life course factors. This material is reviewed in the first section of the paper. The second section reviews the existing literature on housing and health, and finds little work that explicitly investigates housing as a factor in the social production of health inequalities. By extension and analogy, the final section shows, each of the four emphases in health inequalities can be translated into a fruitful, substantive research issue for housing and health research.     

A comparison of the effectiveness of malignancy detection in body fluid examination by the cytopathology and hematology laboratories

BACKGROUND: Body fluid specimens in many institutions are submitted for cytologic examination as well as for examination in a clinical microscopy or hematology laboratory. The cytology laboratory is generally seen as the standard for detection of malignancy, whereas the clinical microscopy laboratory is often depended on predominantly for cell counting and categorization. METHODS: To analyze the effectiveness of the hematology laboratory at detecting malignant fluids, this study retrospectively analyzed reports on 397 body fluid specimens (cerebrospinal, pericardial, peritoneal, and pleural) that were concurrently submitted over a 12-month period to both the cytopathology laboratory and the hematology laboratory. RESULTS: Thirty-seven (9.3%) of the cases were diagnosed as malignant by at least one of the two examinations. The cytopathology examination reported 27 (73%) of the 37 malignant cases as malignant and 30 (81.1%) as at least atypical (27 malignant and 3 inconclusive), and the hematology examination reported 34 (91.9%) as malignant and 36 (97.3%) as at least atypical. A concordant malignant diagnosis was given by both laboratories in 24 (64.9%) of the 37 cases. CONCLUSIONS: These results show that examination of specimens by the hematology laboratory can provide a highly sensitive diagnostic evaluation in addition to its more customary role of providing timely cell counts.