In-laboratory removal of femoral sheath following protamine administration in patients having intracoronary stent implantation

Two hundred twenty-eight patients with successful coronary stent implantation were randomized either to protamine administration and femoral sheath removal (group I, n = 117) or no heparin neutralization and delayed sheath removal (group II, n = 111). The hospital stay after treatment was shorter in patients receiving protamine; therefore, protamine use for neutralizing circulating heparin may be safely administered immediately after stent implantation.     

Characterization of a cartilage-derived 66-kDa protein (RGD-CAP/beta ig-h3) that binds to collagen

Malignant human gliomas are the most common forms of primary tumors in the central nerve system. Due to their location and invasive nature, treatment so far has been mainly palliative. Thus, understanding the molecular detail of tumor transformation and progression is crucial for developing effective therapeutic strategy for this fetal tumor. Among the genetic alternations found in these tumors, p53 inactivation and PDGF/PDGFR activation represent the early events, and the loss of chromosome 10 and gene amplification and rearrangement of EGFR represent the late events. Studies with both glioma cell lines and primary tumor tissues have strongly suggested that TGF-alpha and EGFR function as an important autocrine loop in supporting proliferation of human glioma, especially in high grade glioma, since elevated TGF-alpha expression is also found in these high grade tumors. Furthermore, down regulation of the expression of TGF-alpha by antisense constructs has been shown to inhibit several types of human tumor cell growth including glioma. Other means of therapeutic approaches using this autocrine loop as a target also include the use of monoclonal antibodies and their cytotoxic conjugated. Considerable understanding of the EGFR-mediated signal transduction pathways has become available recently, which including GRB2/mSOS1 mediated MAP kinase activation; JAK/STATs pathway; PLC-gamma pathway. However, much work still needs to be done before a specific component of these pathways can be applied for effective control of tumor growth in the clinic.     

The effect of grain-size on the stress and velocity fields ahead of a crack in a material which deforms by Coble creep

The stress and velocity fields ahead of a grain-boundary crack in a material which deforms by Coble creep are investigated for a series of grain sizes using the numerical analysis technique established by Cocks [1–3]. The numerical results are compared with the linear viscous fields obtained by the boundary element method and the finite element method. It is demonstrated that a detailed knowledge of the micromechanical processes of material transport and deformation are required to determine the stress and displacement fields for the grains which immediately surround the crack tip. But the response of the surrounding material can be adequately described from a conventional linear viscous analysis of the problem.     

二阶A型Cooper变换的增强型

对二阶Ａ型Ｃｏｏｐｅｒ变换进行增强，放宽可用性条件，并证明了其正确性，最后举例说明其应用。     

纸张背衬不同衬底时的光反射率的研究

从理论上研究了纸张背衬不同衬底的光反射率，得出下列表达式：Ｒｂ＝Ｒｏ＋（Ｒ∞－Ｒｏ）×（１／Ｒ∞－Ｒｏ）／（１／Ｂ－Ｒｏ）（Ｂ为衬底的光反射率），该式简单实用且物理意义明确。利用上述公式，可将Ｔａｐｐｉ标准列出的Ｔａｐｐｉ不透明度Ｃ０．８９的换算公式简化，并可从理论上定性地讨论纸张不透明度与印刷透印性的关系。     

米塔尔钢铁集团的全球并购发展战略

概述了米塔尔的并购经过和并购特点,着重探讨了米塔尔的管理模式、人员情况、钢铁厂布局、生产经营、主要战略伙伴、研发机构及其生产、采购与销售策略。系统地分析了米塔尔在中国的发展,指出米塔尔在全球钢铁业整合中处于领先地位,米塔尔来中国投资看中的是中国的原料和市场,且运作步伐明显加快,会对中国钢铁企业构成很大的威胁。     

一个实用、高效网络攻防训练模拟系统的设计与实现

随着信息技术的发展,网络安全问题日益生要,它已经渗透到国家各个领域, 并在未来信息战中扮演不可替代的角色。网络攻防是信息战不可缺少的部分,为了提高安全管理人员的素质,需要构造一个融合安全理论、实践训练于一体的安全体系,因此我们提出了建立网络攻防训练模拟系统,主要由数据库子系统、网上理论学习及考试子系统、网络攻防仿真训练子系统,成果评估子系统组成。这四部分联动融合、形成体系, 构建了以数据库子系统为基础、交互式仿真训练子系统为框架的分市式、全方位、多层次的网上学习、训练、考核体系,可实现网络攻防训练、对抗、理论学习及考核评估等功能。     

Interpretation of scatterometer ocean surface wind vector EOFs over the Northwestern Pacific

Satellite scatterometer winds over the northwestern Pacific were analyzed with the vector empirical orthogonal function (VEOF) method. The Hilbert-Huang transform (HHT), a newly developed non-linear and non-stationary time series data processing method, was also employed in the analysis. A combination of European Remote Sensing Satellite (ERS) −1/2 scatterometer, NASA Scatterometer (NSCAT) and NASA's Quick Scatterometer (QuikSCAT) winds covering the period from January 1992 to April 2000 and the area of 0-50°N, 100-148°E constitutes the baseline for this study. The results indicate that annual cycles dominate the two leading VEOF modes. The first VEOF shows the East Asian monsoon features and the second represents a spring-autumn oscillation. We removed the annual signal from the data set and calculated the interannual VEOFs. The first interannual VEOF represents the interannual variability existing in the spring-autumn oscillation. The temporal mode is correlated with the Southern Oscillation Index (SOI), but has a half-year lag with respect to the SOI. The spatial mode of the first interannual VEOF reflects the response of the tropical and extratropical winds to ENSO events. The second interannual VEOF is another ENSO related mode, and the temporal VEOF mode is correlated with the SOI with a correlation coefficient of 0.78, revealing the wind variability over mid-latitudes, which is associated with ENSO events. Further analysis indicated that the wind variability over the coast of East Asia represents anomalies of a Hadley cell. The quasi-biennial oscillation (QBO) was found in the temporal mode, indicating and verifying that the QBO in the wind fields is related to ENSO events. The third VEOF shows the interannaul variability in the winter-summer mode and displays the interannual variability of the East Asian monsoon. The three leading interannual VEOFs are statistically meaningful as confirmed by a significance test.     

催化裂化技术现状及发展趋势

详述了国内外最新渣油催化裂化、多产柴油催化裂化、低碳烯烃催化裂化、生产清洁燃料催化裂化及催化剂的技术进展，同时根据我国实际情况对今后催化裂化技术的发展提出了建议。