Sense of smell disorder and health-related quality of life.

Objectives: To compare health-related quality of life and depression between individuals with an inability to smell (anosmia) and a comparison group of individuals with a normal sense of smell. Methods: Ninety individuals from an anosmia organization (anosmia based on self-report) were compared to 89 individuals with a normal sense of smell. The SF-36 and Beck Depression Inventory-II-NL (BDI-II-NL) were administered, along with the Questionnaire for Olfactory Dysfunction (QOD) to assess the degree of problems in daily life related to the smell impairment. Results: Compared to the comparison group, scores in the anosmia group differed on: the QOD-subscale Life Quality (related to tasting and smelling: p p Social Functioning, Vitality, Mental Health and General Health (p’s p     

Controlling the spread of smoke in fires

In a building fire it is often the spread of smoke into crucial areas that presents the greatest obstacle to escape. The problem is therefore to control this process, especially in ‘compartmented’, multi-occupation buildings. The principles are discussed here and related to the smoke-control systems currently available throughout the world.     

Human-specific fecal bacteria in wastewater treatment plant effluents

The objective of this study was to identify fecal bacteria able to persist after wastewater treatment and that could be used as indicators of human fecal contamination. In a first step, the diversity of Bacteroidales, Clostridiaceae, Bifidobacterium, and Bacillus-Streptococcus-Lactobacillus cluster (BSL) was analysed using a fingerprint technique (CE-SSCP) and 16S rDNA libraries in waters collected at the end of the treatment process in different urban wastewater treatment plants. For each group, dominant bacteria present in most effluents were identified. Their origin (human feces, animal feces, non-fecal) was then analysed based on data of their closest relatives in public 16S rDNA databases. Among fecal bacteria recovered in the treated effluents analysed, phylotypes close to Bifidobacterium adolescentis and Bacteroides caccae seem to be specific to human beings. Phylotypes gathering only sequences of human fecal origin were also identified among the BSL and Clostridiaceae, two bacterial groups which have been poorly investigated for bacterial source-tracking purpose. Since these bacteria were detected post-treatment in most wastewater treatment plants, they may constitute potential new indicators of fecal contamination specific to humans that could be used to track fecal contamination of surface water by sewage.     

Empirical analysis of maintenance performance measurement in Belgian industries

Performance measurement is a fundamental instrument of management. For maintenance management, one of the key issues is to ensure the maintenance activities planned and executed have given the expected results. This can be facilitated by effective use of rigorously defined key performance indicators (KPI) that are able to measure important aspects of maintenance function. In this paper, an industrial survey was carried out to explore the use of performance measurement in maintenance management. Based on survey responses, analyses were performed on popularly used KPI, how these KPI are sourced or chosen; the influence of manufacturing environment and maintenance objectives on KPI choice and effective use of these KPI in decision support and performance improvement. It was found that maintenance performance measurement is dominated by lagging indicators (equipment, maintenance cost and safety performance). There is lesser use of leading (maintenance work process) indicators. The results showed no direct correlations between the maintenance objectives pursued and the KPI used. Further analysis showed that only a minority of the companies have a high percentage of decisions and changes triggered by KPI use and only a few are satisfied with their performance measurement systems. Correlation analysis showed a strong positive linear relationship between degree of satisfaction and process changes/decisions triggered by KPI use, with the least satisfied people having the least decisions and changes triggered by KPI use. The results indicate some ineffectiveness of performance measurement systems in driving performance improvement in industries.     

Prevalence, quantification and antimicrobial resistance of Campylobacter spp. on chicken neck-skins at points of slaughter in 5 major cities located on 4 continents

Quantitative data on Campylobacter contamination of food are lacking, notably in developing countries. We assessed Campylobacter contamination of chicken neck-skins at points of slaughter in 5 major cities in Africa (Dakar in Senegal, Yaounde in Cameroon), Oceania (Noumea in New Caledonia), the Indian Ocean (Antananarivo in Madagascar) and Asia (Ho Chi Minh City (HCMC) in Vietnam. One hundred and fifty slaughtered chickens were collected in each of the 5 major cities from semi-industrial abattoirs or markets (direct slaughter by the seller), and 65.5% (491/750) were found to be Campylobacter-positive. Two cities, Yaounde and Noumea, demonstrated high prevalence Campylobacter detection rates (92.7% and 96.7% respectively) in contrast with HCMC (15.3%). Four species were identified among 633 isolates, namely C. jejuni (48.3%), C. coli (37.3%), C. lari (11.7%) and C. upsaliensis (1%). HCMC was the only city with C. lari isolation as was Antananarivo for C. upsaliensis. C. coli was highly prevalent only in Yaounde (69.5%). Among the 491 samples positive in Campylobacter detection, 329 were also positive with the enumeration method. The number of Campylobacter colony-forming units (CFU) per gram of neck-skin in samples positive in enumeration was high (mean of the log(10): 3.2 log(10) CFU/g, arithmetic mean: 7900CFU/g). All the cities showed close enumeration means except HCMC with a 1.81 log(10) CFU/g mean for positive samples. Semi-industrial abattoir was linked to a significant lower count of Campylobacter contamination than direct slaughter by the seller (p=0.006). On 546 isolates (546/633, 86.3%) tested for antibiotic susceptibility, resistance to erythromycin, ampicillin and ciprofloxacin was observed for respectively 11%, 19% and 50%. HCMC was the city where antibiotic resistant rates were the highest (95%, p=0.014). Considering the 329 positive chickens in Campylobacter enumeration, the mean number of resistant isolates to at least 2 different antibiotic families (19.8%), may be estimated ca. 1500CFU/g; the corresponding mean of the log(10) would be 2.5 log(10)CFU/g. As chickens are sold at slaughter and brought directly at home to be cooked, these data suggest a high probability of cross-contamination. A substantial proportion of isolates are drug-resistant, which could lead to potential public health issues. Health authorities should consider measures to reduce Campylobacter contamination of chicken during farming and at slaughter, and to provide appropriate food hygiene education. Further studies are needed in particular to investigate food-handling practices in domestic kitchens.     

Identification of metabolic pathways involved in the biosynthesis of flavor compound 3-methylbutanal from leucine catabolism by Carnobacterium maltaromaticum LMA 28

Carnobacterium maltaromaticum strains are widely found in food including fish, meat and some dairy products. Producing a malty/chocolate like aroma due to 3-methylbutanal from the catabolism of leucine is a general characteristic of this species. In this study, we investigated metabolic routes responsible for the biosynthesis of this flavor compound from the catabolism of leucine in C. maltaromaticum LMA 28, a strain isolated from mold ripened soft cheese. Depending on the lactic acid bacterium, leucine can be converted into 3-methylbutanal following two possible metabolic pathways: either directly by α-ketoacid decarboxylase (KADC) pathway or indirectly by α-ketoacid dehydrogenase (KADH) pathway. Both KADC (41.0±3.0 nmol/mg protein/min) and KADH (1.43±0.62 nmol/mg protein/min) activities were detected and determined in vitro in C. maltaromaticum LMA 28. C. maltaromaticum LMA 28 slightly reduced the production of 3-methylbutanal from leucine in the presence of a specific inhibitor of KADH enzyme complex, i.e. sodium meta-arsenite, suggesting that both pathways were involved in vivo in leucine catabolism. Moreover the presence of genes encoding aminotransferase, glutamate dehydrogenase, α-ketoacid decarboxylase, α-ketoacid dehydrogenase and aldehyde dehydrogenase was confirmed. C. maltaromaticum is then the first lactic acid bacterium in which presence of both metabolic routes responsible for the biosynthesis of 3-methylbutanal from leucine catabolism was confirmed in vitro and in vivo as well.     

Influence of sex, maturity and reproduction on PCB and p,p′DDE concentrations and repartitions in the European hake (Merluccius merluccius, L.) from the Gulf of Lions (N.W. Mediterranean)

The main objective of this work was to establish the influence of sex, maturity and reproduction on the contamination of the demersal fish Merluccius merluccius by organochlorine compounds. Polychlorinated biphenyls (PCBs) and p,p′DDE were quantified in muscle, liver and gonads of female and male hakes collected in the Gulf of Lions in 2004 and 2005. Observed levels appeared higher than the population of the Bay of Biscay and lower than the population of the Thyrrenian Sea. Contaminant fingerprints were roughly constant whatever the studied organ and the hake biological condition. Concentrations varied significantly according to the sex and maturity of hakes. Mature specimens were more contaminated than immature, and males presented higher levels than females. This sex effect can be linked to a lower growth rate of males, and a contaminant elimination during female spawning. Gonadal contamination depends on the importance of lipid content and increases with the maturation degree. Although the main organ of energy and PCB storage is the liver, muscle appears as the main contributor to the gonad contamination.     

Personality, child maltreatment, and substance use: Examining correlates of deliberate self-harm among university students.

Despite recent interest in deliberate self-harm (DSH), the majority of DSH studies have been limited to clinical samples and have identified psychological or clinical correlates and neglected general personality factors. The present study examined personality traits, child maltreatment, and substance use as correlates of DSH in a sample of 319 (65.2% women) university students. A related goal was to describe the nature of DSH in university students. Overall, 29.4% of students reported that they had engaged in at least 1 act of DSH, and rates of DSH were similar across men and women. Cutting was the most frequently endorsed type of DSH. Women were more likely to have engaged in cutting than men, whereas men were more likely to have put themselves in a violent situation where risk of harm was high. There were no differences in the number of different types of DSH acts reported by men and women. Hierarchical multiple regression revealed several significant positive correlates of DSH acts, including greater depressive symptoms, higher levels of sensation seeking and openness to experience, a history of emotional abuse, and illicit drug use. These findings have important implications for the assessment and treatment of DSH among university students. (PsycINFO Database Record (c) 2010 APA, all rights reserved)