Phase structure and thermal stability of crosslinked polyurethane elastomers based on well‐defined prepolymers

Taking advantage of the DSC method, general procedures were presented for qualitative and quantitative evaluation of the phase separation degree and the crystalline phase content in polyurethane elastomers with well‐defined structures. Those elastomers were obtained not only in a typical one‐step method but also in the prepolymer method with the use of urethane oligomers with controlled molecular weight distribution (MWD). Prepolymers with well defined chain structures and narrow distributions of their molecular weights (MWD) M _w/M _n = 1.1–1.3 were produced in a multistage method, i.e., in step‐by‐step polyaddition of 2,4‐ and 2,6‐TDI with polyoxyethylenediols or with polycaprolactonediols of varied molecular weights. Isocyanate oligomers obtained at individual stages were then crosslinked with triethanolamine, whereas hydroxyl‐terminated oligomers were crosslinked with 4,4′,4″‐triphenylmethane triisocyanate (Desmodur RE). The obtained polyurethane elastomers were found to be characterized by the presence of five phases: soft phase consisted of flexible polyol‐type segments, crystalline phase made of soft segments, crystalline and amorphous hard phase made of hard segments, and intermediate phase, which was a composition of the soft and hard segments. The polyurethanes obtained out of prepolymers with defined MWD were characterized by better phase separation of the soft segments and increased structural order inside the hard phase as well as by better thermal stability than polyurethanes obtained from the typical one‐step method. The structural effects were also discussed on the thermal properties of the synthesized elastomers as analyzed by the TG and DTA methods. © 2007 Wiley Periodicals, Inc. J Appl PolymSci 104: 1464–1474, 2007     

Influence of high channel doping on the inversion layer electron mobility in strained silicon n-MOSFETs

In this letter, we investigate the dependence of electron inversion layer mobility on high-channel doping required for sub-50-nm MOSFETs in strained silicon (Si), and we compare it to co-processed unstrained Si. For high vertical effective electric field E/sub eff/, the electron mobility in strained Si displays universal behavior and shows enhancement of 1.5-1.7/spl times/ compared to unstrained Si. For low E/sub eff/, the mobility for strained Si devices decreases toward the unstrained Si data due to Coulomb scattering by channel dopants.     

Heat generated during electrochemical double-layer capacitor “self-discharge”

Eight commercial 10F electrochemical double-layer capacitors (EDLCs) were connected together and placed in a container filled with mineral oil. The whole system was placed into a Dewar container. Temperature variation and heat exchanged between the test EDLC and the environment during its charging, discharging, and “self-discharge” were measured, together with voltage U changes. Charge separation during charging was equivalent to a transition into a more ordered system, which results in entropy decrease, while discharging caused entropy increase (the Peltier–Seebeck effect). Consequently, a number of charging/discharging cycles led to a corresponding series of entropy and temperature changes. The final shape of temperature versus time curve during charging/discharging cycles was due to overlapping of irreversible Joule–Lenz and reversible Peltier heats. When charged EDLC was kept under the open-circuit condition, measured heat flow was negligible in comparison to energy loss calculated from potential drop, assuming that energy E accumulated is proportional at any time to voltage to the second power (i.e., E ~ U ²). The result was interpreted assuming that the EDLC “self-discharge” phenomenon is not associated with energy loss by the device, but rather with charge redistribution between EDLC particles characterized by different time constants.     

Physicochemical and sensory properties of kefir containing inulin and oligofructose

This study concerns the physicochemical and sensory analysis of stirred kefirs made at a laboratory scale, in which one‐third of the skim milk powder (SMP) was replaced by different inulins (long chain, native and oligofructose). The reference kefirs contained 12 g/100 g of SMP or whole milk powder. Rheological analysis showed that the kefirs were viscoelastic materials with thixotropic and shear‐thinning behaviour. Rheological data showed that SMP can be successfully substituted by long‐chain inulin; however, sensory evaluation indicated that substitution of SMP by any other kinds of inulin significantly decreased the consistency of kefirs while not affecting their flavour and odour.     

Parathyroid hormone-related peptide (1 to 34) inhibits in vitro oxytocin-stimulated activity of pregnant baboon myometrium

A novel protein kinase that has significant sequence homology to mitogen-activated protein kinase (MAPK)-activated protein kinase (MAPKAPK) was identified. This novel protein kinase has a nucleotide sequence that encodes a protein of 473 amino acids and shares 45%, 46%, and 44% amino acid sequence identities to MAPKAPK2, 3 and 4 respectively. Northern blot analysis revealed that it has a wide tissue distribution. This novel protein kinase designated MAPKAPK5 can be phosphorylated by extracellular-regulated kinase (ERK), and p38 kinase but not by c-jun N-terminal kinase (JNK) in vitro. Recombinant GST-MAPKAPK5 protein can phosphorylate a peptide derived from the regulatory light chain of myosin II. Phosphorylation of MAPKAPK5 by ERK and p38 kinase increased its activity by 9 and 15 fold respectively. Taken together, these data suggest that MAPKAPK5 is a novel in vitro substrate for ERK and p38 kinase.     

Use of Methylmalonyl‐CoA Epimerase in Enhancing Crotonase Stereoselectivity

The use of methylmalonyl‐CoA epimerase (MCEE) to improve stereoselectivity in crotonase‐mediated biocatalysis is exemplified by the coupling of MCEE, crotonyl‐CoA carboxylase reductase and carboxymethylproline synthase in a three‐enzyme one‐pot sequential synthesis of functionalised C‐5 carboxyalkylprolines starting from crotonyl‐CoA and carbon dioxide.