Wireless body area network (WBAN) has witnessed significant attentions in the healthcare domain using biomedical sensor-based monitoring of heterogeneous nature of vital signs of a patient’s body. The design of frequency band, MAC superframe structure, and slots allocation to the heterogeneous nature of the patient’s packets have become the challenging problems in WBAN due to the diverse QoS requirements. In this context, this paper proposes an Energy Efficient Traffic Prioritization for Medium Access Control (EETP-MAC) protocol, which provides sufficient slots with higher bandwidth and guard bands to avoid channels interference causing longer delay. Specifically, the design of EETP-MAC is broadly divided in to four folds. Firstly, patient data traffic prioritization is presented with broad categorization including Non-Constrained Data (NCD), Delay-Constrained Data (DCD), Reliability-Constrained Data (RCD) and Critical Data (CD). Secondly, a modified superframe structure design is proposed for effectively handling the traffic prioritization. Thirdly, threshold based slot allocation technique is developed to reduce contention by effectively quantifying criticality on patient data. Forth, an energy efficient frame design is presented focusing on beacon interval, superframe duration, and packet size and inactive period. Simulations are performed to comparatively evaluate the performance of the proposed EETP-MAC with the state-of-the-art MAC protocols. The comparative evaluation attests the benefit of EETP-MAC in terms of efficient slot allocation resulting in lower delay and energy consumption.
The COVID-19 pandemic has affected the educational systems worldwide, leading to the near-total closures of schools, universities, and colleges. Universities need to adapt to changes to face this crisis without negatively affecting students’ performance. Accordingly, the purpose of this study is to identify and help solve to critical challenges and factors that influence the e-learning system for Computer Maintenance courses during the COVID-19 pandemic. The paper examines the effect of a hybrid modeling approach that uses Cloud Computing Services (CCS) and Virtual Reality (VR) in a Virtual Cloud Learning Environment (VCLE) system. The VCLE system provides students with various utilities and educational services such as presentation slides/text, data sharing, assignments, quizzes/tests, and chatrooms. In addition, learning through VR enables the students to simulate physical presence, and they respond well to VR environments that are closer to reality as they feel that they are an integral part of the environment. Also, the research presents a rubric assessment that the students can use to reflect on the skills they used during the course. The research findings offer useful suggestions for enabling students to become acquainted with the proposed system’s usage, especially during the COVID-19 pandemic, and for improving student achievement more than the traditional methods of learning. 相似文献
This paper presents a robust, efficient and parameter-setting-free evolutionary approach for the optimal design of compact heat exchangers. A learning automata based particle swarm optimization (LAPSO) is developed for optimization task. Seven design parameters, including discreet and continuous ones, are considered as optimization variables. To make the constraint handling straightforward, a self-adaptive penalty function method is employed. The efficiency and the accuracy of the proposed method are demonstrated through two illustrative examples that include three objectives, namely minimum total annual cost, minimum weight and minimum number of entropy generation units. Numerical results indicate that the presented approach generates the optimum configuration with higher accuracy and a higher success rate when compared with genetic algorithms (GAs) and particle swarm optimization (PSO). 相似文献
A convenient synthesis of imatinib, a potent inhibitor of ABL1 kinase and widely prescribed drug for the treatment of a variety of leukemias, was devised and applied to the construction of a series of novel imatinib analogues featuring a number of non‐aromatic structural motifs in place of the parent molecule's phenyl moiety. These analogues were subsequently evaluated for their biopharmaceutical properties (e.g., ABL1 kinase inhibitory activity, cytotoxicity). The bicyclo[1.1.1]pentane‐ and cubane‐containing analogues were found to possess higher themodynamic solubility, whereas cubane‐ and cyclohexyl‐containing analogues exhibited the highest inhibitory activity against ABL1 kinase and the most potent cytotoxicity values against cancer cell lines K562 and SUP‐B15. Molecular modeling was employed to rationalize the weak activity of the compounds against ABL1 kinase, and it is likely that the observed cytotoxicity of these agents arises through off‐target effects. 相似文献
The link between movement abnormalities and psychotic disorders is presumed to reflect common neural mechanisms that influence both motor functions and vulnerability to psychosis. The prodromal period leading to psychotic disorders represents both a viable point for intervention and a developmental period that, if studied, could shed light on etiology; however, no published studies have examined the temporal progression of this link. A group with high levels of prodromal symptomatology (i.e., adolescents with schizotypal personality disorder [SPD]; n = 42) and both psychiatric controls (with other personality disorders or conduct disorder [OD]; n = 30) and nonpsychiatric controls ([NC]; n = 49) were recruited. Videotapes of structured psychiatric interviews were coded for movement abnormalities by raters blind to participants' diagnostic status, and follow-up assessments were conducted 1 year later. Controlling for psychotropic medications, the authors found that adolescents with SPD exhibited significantly more motor abnormalities in the face and upper body than did OD and NC controls. At baseline, movement abnormalities were positively correlated with the severity of positive, negative, and total prodromal symptoms. Within the SPD group, baseline movement abnormalities predicted symptom severity 1 year later. Movement abnormalities represent an early risk indicator that may be predictive of later symptom severity and potentially of psychosis onset. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
The viscoelastic nature of bulk metallic glasses (BMGs), their low thermal conductivity, and the fast cooling used in their
processing subject them to thermal tempering. This process leads to a residual stress state in which compression on the surface is balanced by tension in the interior.
For the first time, we have calculated such stresses in metallic glasses by adapting an analytical instant-freezing model
previously developed for silicate glasses. This model has been demonstrated to be reasonably accurate in predicting the final
residual stresses, although, due to its very nature, it neglects transient effects. For an infinite plate geometry and employing
processing parameters often used for metallic glasses, we predict that significant residual stresses can be generated in these
materials during thermal tempering. Preliminary measurements conducted using the layer-removal method yield compressive residual
stress values close to model predictions. 相似文献
Branch and bound algorithms for Mixed-Integer Linear Programming (MILP) almost universally branch on a single variable to create disjunctions. General linear expressions involving multiple variables are another option for branching disjunctions, but are not used for two main reasons: (i) descendent LPs tend to solve more slowly because of the added constraints, so the overall solution time is increased, and (ii) it is difficult to quickly find an effective general disjunction. We study the use of general disjunctions to reach the first MILP-feasible solution quickly, showing for the first time that general disjunctions can provide speed improvements for hard MILP models. The speed-up is due to new and efficient ways to (i) trigger the inclusion of a general disjunction only when it is likely to be beneficial, and (ii) construct effective general disjunctions very quickly. Our empirical results show performance improvements versus a state of the art commercial MILP solver. 相似文献
Estimating point-to-point demands from partially available information, such as total demand volumes originating and terminating at nodes and traffic volumes routed on links, has significant applications in various areas, such as communications network planning and transportation planning. Existing methods include matrix and link scaling methods, statistical methods, more complex mathematical programming models, and forecasting using demographic data. We present a new mathematical programming model based on equitable resource allocation. The model considers multiple services, e.g., data, video, and voice, and generates a point-to-point demand matrix for each service. Originating and terminating demands for each service and link loads, aggregated over all services, are viewed as resources. Each point-to-point demand is associated with a performance function that measures its weighted, normalized deviation from a target defined by a service-dependent community of interest matrix. The model formulation has a lexicographic minimax objective function and multiple knapsack resource constraints. The model has an intuitively appealing interpretation and a specialized algorithm can generate demand matrices for large network problems very fast. 相似文献