Developmental factors in the treatment on adolescents.

Most empirically supported interventions for adolescent mental health problems are either downward adaptations of adult treatments or upward adaptations of child treatments. Although these treatments show respectable effects with teens, a review of the outcome research reveals significant gaps, both in coverage of adolescent conditions and problems (e.g., eating disorders, suicidality) and in attention to the biological, psychological, and social dimensions of adolescent development. The authors critique the field, propose a biopsychosocial framework for the development of dysfunction and intervention, and discuss ways the developmental literature can and cannot inform intervention and research. A long-term goal is an array of developmentally tailored treatments that are effective with clinically referred teens and an enriched understanding of when, how, and why the treatments work. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Teaching reading to poor readers in the intermediate grades: A comparison of text difficulty.

The authors compared the influence of text difficulty--reading-level matched or grade-level matched--on the growth of poor readers' reading ability over 18 weeks of 1-to-1 tutoring. Forty-six 3rd-5th graders, including 25 with disabilities, were assigned randomly to 1 of 2 tutoring approaches or a control condition. Significant differences favored tutored children. Between approaches, the only significant difference was oral reading fluency, which favored students who read material at their reading level. Students who began with lower fluency made stronger gains in text matched to reading level; students with higher fluency profited from both treatments. When the 3 groups were combined, fluency was the strongest contributor to reading comprehension outcomes. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

The Influence of Race in Police–Civilian Interactions: A Content Analysis of Videotaped Interactions Taken During Cincinnati Police Traffic Stops

Although the study of police–civilian relations has recently entered the intergroup communication arena, there are no studies of actual interactions between these social categories. In part to rectify that stark omission and guided by communication accommodation theory, 313 randomly sampled video recordings from police cars on traffic stops in Cincinnati, Ohio were content analyzed. The study revealed 3 key differences as a function of the officers' and drivers' races: (a) Black drivers were more likely to experience extensive policing during the stop; (b) the communication quality of White drivers was, on average, more positive than that of the Black drivers; and (c) officers' communication behavior was more positive when the officer and driver were of the same race. These findings are consistent with public opinion data and their implications for theory are discussed.     

On satisfying due-dates in large job shops: idle time insertion

We consider the problem of minimizing maximum lateness in a job shop. A conceptually simple simulation based procedure described in a recent paper by Hodgson et al [1] is modified to provide improved schedules. Computational experimentation is provided to identify the conditions under which the approach is most viable, and to report the procedure's performance on known test problems.     

The critical role of conflict resolution in teams: A close look at the links between conflict type, conflict management strategies, and team outcomes.

[Correction Notice: An erratum for this article was reported in Vol 93(2) of Journal of Applied Psychology (see record 2008-02855-019). Figure 2 on p. 184 (Theoretical Contributions section) is missing information about the numbers of teams and statements for the two groups using particularlistic strategies. For the decreasing and consistently low performance/decreasing and consistently low satisfaction group, there were 14 teams and 40 statements; for the decreasing and consistently low performance/increasing and consistently high satisfaction group, there were 11 teams and 46 statements.] This article explores the linkages between strategies for managing different types of conflict and group performance and satisfaction. Results from a qualitative study of 57 autonomous teams suggest that groups that improve or maintain top performance over time share 3 conflict resolution tendencies: (a) focusing on the content of interpersonal interactions rather than delivery style, (b) explicitly discussing reasons behind any decisions reached in accepting and distributing work assignments, and (c) assigning work to members who have the relevant task expertise rather than assigning by other common means such as volunteering, default, or convenience. The authors' results also suggest that teams that are successful over time are likely to be both proactive in anticipating the need for conflict resolution and pluralistic in developing conflict resolution strategies that apply to all group members. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Flame retardancy mechanisms of triphenyl phosphate,resorcinol bis(diphenyl phosphate) and bisphenol A bis(diphenyl phosphate) in polycarbonate/acrylonitrile–butadiene–styrene blends

The flame retardancy mechanisms of three aryl phosphates, triphenyl phosphate (TPP), resorcinol bis(diphenyl phosphate) (RDP) and bisphenol A bis(diphenyl phosphate) (BDP), in a polycarbonate/acrylonitrile–butadiene–styrene (PC/ABS) blend are investigated and compared. Further, the influence of polytetrafluorethylene (PTFE) on viscosity and thermal decomposition is discussed in the systems PC/ABS and PC/ABS + BDP. Mechanisms are proposed based on the results of various methods. Thermogravimetric analysis, Fourier transform infrared spectroscopy and kinetics are used to study the pyrolysis. The fire behaviour is studied by means of cone calorimeter measurements at different heat fluxes and the flammability is specified by limiting oxygen index (LOI) and UL 94. Rheology measurements are used to illuminate the changed dripping behaviour due to PTFE. TPP shows only a gas phase action. RDP shows mainly a gas phase action and some condensed phase action. BDP shows a crucial condensed phase action in addition to a gas phase action. TPP and RDP are somewhat superior in terms of flammability (LOI), whereas BDP shows superior performance in forced flaming combustion (cone calorimeter). Synergistic effects between PTFE and BDP are found. Copyright © 2007 Society of Chemical Industry     

Iron‐Catalyzed Epoxidation of Aromatic Olefins and 1,3‐Dienes

The combination of iron(III) chloride, pyridine‐2,6‐dicarboxylic acid and formamidine ligands allows for the epoxidation of styrenes and conjugated dienes in excellent chemoselectivity and yields.     

Inhibition of Eimeria tenella CDK‐Related Kinase 2: From Target Identification to Lead Compounds

Apicomplexan parasites encompass several human‐ and animal‐pathogenic protozoans such as Plasmodium falciparum, Toxoplasma gondii, and Eimeria tenella. E. tenella causes coccidiosis, a disease that afflicts chickens, leading to tremendous economic losses to the global poultry industry. The considerable increase in drug resistance makes it necessary to develop new therapeutic strategies against this parasite. Cyclin‐dependent kinases (CDKs) are key molecules in cell‐cycle regulation and are therefore prominent target proteins in parasitic diseases. Bioinformatics analysis revealed four potential CDK‐like proteins, of which one—E. tenella CDK‐related kinase 2 (EtCRK2)—has already been characterized by gene cloning and expression. 1 By using the CDK‐specific inhibitor flavopiridol in EtCRK2 enzyme assays and schizont maturation assays (SMA), we could chemically validate CDK‐like proteins as potential drug targets. An X‐ray crystal structure of human CDK2 (HsCDK2) served as a template to build protein models of EtCRK2 by comparative homology modeling. Structural differences in the ATP binding site between EtCRK2 and HsCDK2, as well as chicken CDK3, were addressed for the optimization of selective ATP‐competitive inhibitors. Virtual screening and “wet‐bench” high‐throughput screening campaigns on large compound libraries resulted in an initial set of hit compounds. These compounds were further analyzed and characterized, leading to a set of four promising lead compounds for development as EtCRK2 inhibitors.     

Application of proteomics to understand the molecular mechanisms behind meat quality

The proteome is expressed from the genome, influenced by environmental and processing conditions, and can be seen as the molecular link between the genome and the functional quality characteristics of the meat. In contrast to traditional biochemical methods where one protein is studied at a time, several hundred proteins can be studied simultaneously. Proteomics is a promising and powerful tool in meat science and this is reflected by the increasing number of studies emerging in the literature using proteomics as the key tool to unleash the molecular mechanisms behind different genetic backgrounds or processing techniques of meat. Thus understanding the variations and different components of the proteome with regard to a certain meat quality or process parameter will lead to knowledge that can be used in optimising the conversion of muscles to meat. At present, there has been focus on development of techniques and mapping of proteomes according to genotypes and muscle types. In the future, focus should be more towards understanding and finding markers for meat quality traits. This review will focus on the methods used in the published proteome analyses of meat, with emphasis on the challenges related to statistical analysis of proteome data, and on the different topics of meat science that are investigated.