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61.
Only very few radionuclides exist that decay exclusively by EC-mode without accompanying radiation, 119Sb is one of them. Auger emitter 119Sb (T1/2 = 38.9 h, IEC = 100%) is a potent nuclide for targeted radionuclide therapy based on theoretical dosimetry calculations at a subcellular scale. Auger electron emitting radionuclides in cancer therapy offer the opportunity to deliver a high radiation dose to the tumor cells with high radiotoxicity while minimizing toxicity to normal tissue.  相似文献   
62.
In current research, fractal theory has been applied for estimation of shrinkage of osmotically dehydrated and air-dried kiwifruit using a combination of neural network and genetic algorithm. Kiwifruits were dehydrated at different conditions and digital images of final dried products were taken. Kiwifruit-background interface lines were detected using a threshold combined with an edge detection approach and their corresponding fractal dimensions were calculated based on a box counting method. A neural network was constructed using fractal dimension and moisture content as inputs to predict shrinkage of dried kiwifruit and a genetic algorithm was applied for optimization of the neural network's parameters. The results indicated good accuracy of optimal model (correlation coefficient of 0.95) and high potential application of fractal theory and described intelligent model for shrinkage estimation of dried kiwifruit.  相似文献   
63.
This paper investigates the compression and recovery properties of the rugs by highlighting the base zone effect. To fulfill this purpose, a new type of rug named Double-Base Persian Rug was prepared. In the new rug, the warping was done such that we have two sets of warp sheets (back base and front base warp yarns). So that, a gap between these two bases were created that could be filled with various types of fillers. A total of seven rug samples; a conventional Persian rug as the base of comparison and six new types of rug samples were produced. Then, the compression and recovery properties of the rug samples were investigated by static loading test. Generally, the results indicated that the rug base structure and the inherent characteristics of the materials used in the rug base as a filler positive affect the rug compression and recovery properties.  相似文献   
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The PI3K/mTOR signalling pathway plays a central role in the governing of cell growth, survival and metabolism. As such, it must integrate and decode information from both external and internal sources to guide efficient decision-making by the cell. To facilitate this, the pathway has evolved an intricate web of complex regulatory mechanisms and elaborate crosstalk with neighbouring signalling pathways, making it a highly non-linear system. Here, we describe the mechanistic biological details that underpin these regulatory mechanisms, covering a multitude of negative and positive feedback loops, feed-forward loops, competing protein interactions, and crosstalk with major signalling pathways. Further, we highlight the non-linear and dynamic network behaviours that arise from these regulations, uncovered through computational and experimental studies. Given the pivotal role of the PI3K/mTOR network in cellular homeostasis and its frequent dysregulation in pathologies including cancer and diabetes, a coherent and systems-level understanding of the complex regulation and consequential dynamic signalling behaviours within this network is imperative for advancing biology and development of new therapeutic approaches.  相似文献   
66.
In this paper, a unified analytical approach is applied to investigate the vibrational behavior of composite cylindrical shells. Theoretical formulation is established based on Sanders’ thin shell theory. The modal forms are assumed to have the axial dependency in the form of Fourier series whose derivatives are legitimized using Stoke's transformation. The Influence of some commonly used boundary conditions and the effect of variations in shell geometrical parameters on the shell frequencies are studied. The results obtained for a number of particular cases show good agreement with those available in the open literature. The simplicity and the capability of the present method are also discussed.  相似文献   
67.
Perovskite surface treatment with additives has been reported to improve charge extraction, stability, and/or surface passivation. In this study, treatment of a 3D perovskite ((FAPbI3)1−x(MAPbBr3)x) layer with a thienothiophene-based organic cation (TTMAI), synthesized in this work, is investigated. Detailed analyses reveal that a 2D (n = 1) or quasi-2D layer does not form on the PbI2-rich surface 3D perovskite. TTMAI-treated 3D perovskite solar cells (PSCs) fabricated in this study show improved fill factors, providing an increase in their power conversion efficiencies (PCEs) from 17% to over 20%. It is demonstrated that the enhancement is due to better hole extraction by drift-diffusion simulations. Furthermore, thanks to the hydrophobic nature of the TTMAI, PSC maintains 82% of its initial PCE under 15% humidity for over 380 h (the reference retains 38%). Additionally, semitransparent cells are demonstrated reaching 17.9% PCE with treated 3D perovskite, which is one of the highest reported efficiencies for double cationic 3D perovskites. Moreover, the semitransparent 3D PSC (TTMAI-treated) maintains 87% of its initial efficiency for six weeks (>1000 h) when kept in the dark at room temperature. These results clearly show that this study fills a critical void in perovskite research where highly efficient and stable semitransparent perovskite solar cells are scarce.  相似文献   
68.
Polymer Bulletin - Alumina nanoparticles are among important metal oxides with specific properties but chemically incompatible with an organic matrix such as poly(methyl methacrylate) (PMMA). In...  相似文献   
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Networks and Spatial Economics - Travel demand can be viewed as a weighted and directed graph where nodes are the origins and destinations and links represent the trips between nodes. This paper...  相似文献   
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