The BsmI vitamin D receptor restriction fragment length polymorphism (bb) influences the effect of calcium intake on bone mineral density

Previous studies of the vitamin D receptor (VDR) polymorphisms and bone mineral density (BMD) have suggested that there may be differences in calcium absorption among groups of women with different VDR genotypes, and that the association may be stronger in younger women. To investigate the association between the VDR polymorphisms and BMD, this study was undertaken in the Framingham Study Cohort and a group of younger volunteers. Subjects from the Framingham Study (ages 69-90 years) included those who underwent BMD testing and who had genotyping for the VDR alleles (n = 328) using polymerase chain reaction methods and restriction fragment length polymorphisms with BsmI (B absence, b presence of cut site). A group of younger volunteer subjects (ages 18-68) also underwent BMD testing and VDR genotyping (n = 94). In Framingham Cohort subjects with the bb genotype, but not the Bb or BB genotypes, there were significant associations between calcium intake and BMD at five of six skeletal sites, such that BMD was 7-12% higher in those with dietary calcium intakes greater than 800 mg/day compared with those with intakes < 500 mg/day. The data also suggested that BMD was higher in persons with the bb genotype only in the group with calcium intakes above 800 mg/day. No significant differences were found in the Framingham Cohort for age-, sex-, and weight-adjusted BMD at any skeletal site between those with the BB genotype and those with the bb genotype regardless of 25-hydroxyvitamin D levels or country of origin. In the younger volunteers, BMD of the femoral neck was 5.4% higher (p < 0.05) in the bb genotype group compared with the BB group and 11% higher (p < 0.05) in males with the bb genotype compared with the BB group. There were no significant differences at the lumbar spine. In this study, the association between calcium intake and BMD appeared to be dependent upon VDR genotype. The findings of an association between dietary calcium intake and BMD only in the bb genotype group suggests that the VDR genotype may play a role in the absorption of dietary calcium. Studies that do not consider calcium intake may not detect associations between VDR genotype and BMD. In addition, the association between VDR alleles and BMD may become less evident in older subjects.     

微电热新技术及其在食品加工领域中的应用前景

ＤＺＲ是新型微电热材料的简称，其发明人是孔德凯先生，该材料已先后获美国、澳大利亚、英国、法国、意大利、瑞典、日本等国专利。发明人的杰出贡献在于不仅找到了ＤＺＲ材料的制造方法，而且实现了元件和部件的系列化和标准化，并提出了微球理论，创立了孔氏面电阻定律、面热材料功率计算定律、寿命计算定律，引起了各国的极大关注。本文阐述了国内外电热材料研究概况及国际发明专利ＤＺＲ技术特点及其在食品加工领域中应用前景。     

高应力水平下滚动轴承疲劳寿命试验研究

通过在三种不同的强化负荷下进行深沟球轴承疲劳寿命试验，并与常规试验一组结果对比。结果表明，适当地加大滚动轴承疲劳寿命试验负荷，可以大大缩短试验时间，而疲劳寿命依然服从Ｗｅｉｂｕｌ分布，且与常规试验结果基本一致，同时疲劳破坏的形式仍是表面下萌生裂纹，然后扩展至表面形成剥落。     

光折变晶体Cu:KNSBN的多重图像存贮实验研究

目前,光折变非线性元件在光学并行图像处理中有着非常广泛的应用。光折变晶体用于图像边缘增强,图像加、减运算,非相干—相干转换(PICOC),图像相关和卷积运算等研究已取得显著成果。本文研究了Cu;KNSBN晶体中多重图像的存贮问题,指出可以利用这种技术实现光学目标识别并给出了一些初步实验结果。此外,还从理论上分析了具有相同衍射效率的多重全息信息记录技术。     

Application of the spline finite strip to the analysis of shear-deformable plates

A spline finite strip is proposed to analyse thick isotropic or laminated composite plates. The formulation is based upon the principle of virtual work and the third-order plate theory developed by Reddy. The variational functional requires the satisfaction of C₁,-continuity of the assumed vertical deflection variable which can be easily fulfilled by the present method. The proposed spline finite strip is a conforming element with a smaller number of unknowns at each node compared to other existing elements based on the third-order theory. For the analysis of thin isotropic or laminated plates, the present element shows no sign of shear locking. A number of computational examples are given to demonstrate the efficiency and the accuracy of the present method.     

CTS-26型超声探伤仪典型故障的分析与排除

在简要介绍CTS-26型超声探伤仪工作原理及组成的基础上。对其几种典型故障作了具体的分析和处理。     

建筑话语权,离我们多远? --第6届中国(上海)国际房地产与建筑科技展览会侧记

12月3~5日,被誉为“中国住宅产业的奥林匹克”的中国住交会在上海浦东的新国际博览中心粉墨登场,与前5次大会相比,这次大会无论规模还是人气都是空前的。据悉,这次共有来自中国、新加坡、韩国、日本等11个国家的253家机构参加。在住交会上,房地产巨头一直是我们关注的焦点,鲜有     

解读维克斯纳视觉艺术中心

维克斯纳视觉艺术中心在彼得·艾森曼的理论与实践中具有里程碑的地位,试图通过解读视觉艺术中心,探寻艾氏设计思维的核心体系。