Comparison tests for plasma viscosity measurements

The present study measured plasma viscosity using three different viscometers: Ostwald capillary-tube viscometer, Brookfield rotating viscometer, and scanning capillary-tube viscometer (SCTV). The plasma viscosity data obtained using Ostwald viscometer at 37 °C with the conversion constant provided by its manufacturer were in good agreement with those obtained using Brookfield viscometer at 37 °C. In addition, the plasma viscosity data obtained using SCTV were in excellent agreement with those from Brookfield viscometer. However, when the Ostwald viscometer is used for plasma viscosity measurements at the room temperature, one should be cautioned because the conversion constant provided by manufacturers may not be applicable to the room temperature as the surface tension of plasma depends on temperature, affecting the accuracy of the plasma viscosity measurement.     

Exploring the effect of dual use on the value of military technology patents based on the renewal decision

Concerns regarding the high level of research and development (R&D) expenditure on military technology have prompted many nations to pursue a dual-use regime in military R&D. However, the value of dual-use military technology has not yet been quantitatively investigated. We explore whether military technology with a higher level of duality has been more valuable than that with a lower level of duality. We assume that the patent of valuable military technology was renewed until its termination. We retrieve military patents from the United States Patent and Trademark Office during 1976–2014 based on their International Patent Classification (IPC) as F41 or F42. Then, we propose three indicators to assess the duality level of them. The first indicator is based on the determination of whether the patented technology is utilizable in both the military and the civilian sectors using its IPC. For the second indicator, we estimate the potential of convergence of a patented technology with various technological fields using the degree of centrality of the IPC’s co-occurrence network. The third indicator is based on ratio of forward citation by the civilian sector over the total number of forward citations as a measurement of technology diffusion toward the civilian sector. Using logistic regression, we found that the first two indicators are positively associated with patent renewal decision, while the last indicator is nonsignificant. The effects of the two significant indicators suggests that military technologies are more valuable when the technology itself can be used in various sectors, including the civilian sector, and can be converged with technologies in different fields. However, the nonsignificant influence of the third variable suggests that the relation between patent value and diffusion effects toward following inventions is not confined to the civilian sector. Our findings provide evidence of the impact of dual-use policies in military R&D.     

Physicochemical properties,antioxidant activity and inhibition of α‐glucosidase of a novel fermented pepper (Capsiccum annuum L.) leaves‐based vinegar

The aim of this study was to utilise by‐product pepper leaves for vinegar production due to its nutritional value. Changes in physicochemical and functional properties in four main process from raw material (leaves) to lactic acid (juice), alcohol (wine) and acetic acid (vinegar) fermentations were evaluated and compared. Their nutritional compositions were significantly different and particularly the wine and vinegar had higher total phenol content and their expanded diversity than the juice and then leaves (P < 0.05). Difference in values for phenolic compound was highly correlated with their α‐glucosidase inhibitory (AGI) and antioxidant capacities in DPPH and superoxide radical scavenging and reducing power assays (r = 0.919–0.981); vinegar ≥ wine > juice > leaves. Especially, AGI activity was greatly enhanced depending on fermentation steps beyond expectation. Thus, these data confirm that pepper leaves is a good functional source and the vinegar fermentation improved the functionality in stages.     

Finite element modeling of the human cervical spinal column: Role of the uncovertebral joint

Journal of Mechanical Science and Technology - The cervical intervertebral disc has a unique feature in that a fissure or cleft runs along the uncinate process toward the nucleus pulposus called...     

8-Alkylcoumarins from the Fruits of Cnidium monnieri Protect against Hydrogen Peroxide Induced Oxidative Stress Damage

Three new 8-alkylcoumarins, 7-O-methylphellodenol-B (1), 7-methoxy-8-(3-methyl-2,3-epoxy-1-oxobutyl)chromen-2-one (2), and 3′-O-methylvaginol (3), together with seven known compounds (4–10) were isolated from the fruits of Cnidium monnieri. Their structures were determined by detailed analysis of spectroscopic data and comparison with the data of known analogues. All the isolates were evaluated the cytoprotective activity by MTS cell proliferation assay and the results showed that all the three new 8-alkylcoumarins exhibited cytoprotective effect on Neuro-2a neuroblastoma cells injured by hydrogen peroxide.     

A comparative study on the antioxidative and anti‐allergic activities of fresh and aged black garlic extracts

The antioxidative and anti‐allergic activities of fresh and aged black garlic extracts were investigated. The garlic samples were extracted with 70% ethanol (v/v) and the total phenolic content was measured. The antioxidant capacity of extracts was assessed by determining the scavenging activities on 1,1‐diphenyl‐2‐picrylhydrazyl and hydroxyl radicals, ferricyanide reducing power, ferrous ion‐chelating ability and inhibitory effect on linoleic acid peroxidation. The anti‐allergic activity of extracts was analysed by measuring their inhibitory effects against β‐hexosaminidase release. The aged black garlic exhibited significantly higher phenolic content and greater antioxidative activity than fresh garlic. Both garlic extracts showed strong antioxidant capacity in a dose‐dependent manner. On the other hand, a considerably higher suppression of β‐hexosaminidase release was found in fresh garlic extract at lower concentration compared with that of the black garlic. Results of this study illustrate that ageing of garlic could enhance its antioxidant capacity, but could decrease its anti‐allergic activity.     

A vacuum-sealed miniature X-ray tube based on carbon nanotube field emitters

ABSTRACT: A vacuum-sealed miniature X-ray tube based on a carbon nanotube field-emission electron source has been demonstrated. The diameter of the X-ray tube is 10 mm; the total length of the tube is 50 mm, and no external vacuum pump is required for the operation. The maximum tube voltage reaches up to 70 kV, and the X-ray tube generates intense X-rays with the air kerma strength of 108 Gy * cm2 min1. In addition, X-rays produced from the miniature X-ray tube have a comparatively uniform spatial dose distribution.     

High-temperature strength and damage evolution in short fiber reinforced aluminum alloys studied by miniature creep testing and synchrotron microtomography

The creep behavior of a squeeze-cast, short fiber reinforced Al metal matrix composite (MMC), consisting of an Al-11 wt.% Zn-0.2 wt.% Mg alloy reinforced with 15 vol.% Al₂O₃ Saffil® short fibers is investigated using miniature creep specimens. The small dimensions of the miniature creep specimens permit them to be machined from regions of an MMC block with different microstructures, thus allowing the effect of grain size and fiber texture on creep to be investigated on a more local level than is possible using conventional specimen geometries. The miniature creep specimens are subjected to uniaxial tensile stresses ranging from 3 to 40 MPa at temperatures between 573 and 623 K. It is shown that tests performed using the miniature creep specimen geometry are in good agreement with results previously obtained with standard creep specimens. Through interrupted creep experiments, it is observed that the creep back flow that occurs after unloading increases with increasing accumulated plastic strain. In the as-cast MMC, synchrotron microtomography reveals a fine distribution of pores whose spatial density increases with the spatial density of the fibers. The presence of fractured fibers in the crept MMC is also revealed. Some of the regions between fractured fiber fragments appear to be filled with matrix material, while others are voided.     

Inhibitory effect of chloroform on fermentative hydrogen and methane production from lipid-extracted microalgae

To improve the sustainability of microalgae as a bioenergy feedstock, lipid-extracted microalgae (LEM) are often further treated by anaerobic digestion (AD). However, the residual chloroform used for extracting lipids as a solvent could inhibit this process, an aspect that has not been studied to date. In this study, the inhibitory effect of chloroform on H₂ and CH₄ production was investigated by performing batch tests. To prepare the feedstock, Chlorella vulgaris was ultrasonicated and the supernatant was discarded after centrifugation. In case of H₂ production, it was found that the H₂ yield fell to almost half that of the control (15.6 mL H₂/g COD_added) at 100 mg CHCl₃/L. The reason for the decrease of the H₂ yield with the increase of chloroform level was due to the change of metabolites from acetate and butyrate to lactate via a non-hydrogenic reaction. In comparison with H₂ production, a much more severe inhibitory effect of chloroform on CH₄ production was observed. The inhibitor concentration (IC_{30, 60, and 90}) on H₂ production was 138, 319, and 622 mg CHCl₃/L, respectively, while concentrations of 15, 37, and 86 mg CHCl₃/L were obtained on CH₄ production. When the chloroform concentration was ≥25 mg/L on CH₄ production, more than 2 g COD/L of organic acids remained, resulting in a decrease of CH₄ yield. These findings indicate that the residual chloroform in LEM should be seriously considered to prevent possible microbial inhibition when designing a process for additional energy recovery from microalgae via AD.