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排序方式: 共有885条查询结果,搜索用时 15 毫秒
131.
Koyama S Haniu H Osaka K Koyama H Kuroiwa N Endo M Kim YA Hayashi T 《Small (Weinheim an der Bergstrasse, Germany)》2006,2(12):1406-1411
Carbon nanotubes hold great promise for use in biomedical fields. Among numerous potential applications, including DNA and protein sensors, bioseparators, biocatalysts, and tissue scaffolds, this article emphasizes the use of carbon-nanotube-filled polymer composites as medical devices, namely, microcatheters. The currently hot topic of the biocompatibility (e.g., toxic properties) of carbon nanotubes is discussed. In addition, critical issues that must be clarified for the full utilization of current carbon-nanotube science and technology in biomedical fields are discussed. 相似文献
132.
133.
We consider the problem of determining the equilibrium of composite strands consisting of a single core yarn surrounded by n-helical side yarns with pre-twists in the absence of any external load: the self-equilibrium configuration (SEC). We formulate the self-equilibrium problem on the basis of the Kirchhoff rod model in which the contact between yarns in three-dimensional space is taken into account in order to include large helical angles and geometrical constraints. We numerically determine the SECs and elucidate the effect of the following factors on them: the pre-twist of each yarn, the ratio of Young’s modulus of the core yarn to that of the side yarn, and the number of side yarns. The present results allow us to characterize the initial unloaded state of composite strands. 相似文献
134.
Nabeshi H Yoshikawa T Matsuyama K Nakazato Y Arimori A Isobe M Tochigi S Kondoh S Hirai T Akase T Yamashita T Yamashita K Yoshida T Nagano K Abe Y Yoshioka Y Kamada H Imazawa T Itoh N Kondoh M Yagi K Mayumi T Tsunoda S Tsutsumi Y 《Nanotechnology》2012,23(4):045101
We previously reported that well-dispersed amorphous nanosilicas with particle size 70 nm (nSP70) penetrate skin and produce systemic exposure after topical application. These findings underscore the need to examine biological effects after systemic exposure to nanosilicas. The present study was designed to examine the biological effects. BALB/c mice were intravenously injected with amorphous nanosilicas of sizes 70, 100, 300, 1000 nm and then assessed for survival, blood biochemistry, and coagulation. As a result, injection of nSP70 caused fatal toxicity, liver damage, and platelet depletion, suggesting that nSP70 caused consumptive coagulopathy. Additionally, nSP70 exerts procoagulant activity in vitro associated with an increase in specific surface area, which increases as diameter reduces. In contrast, nSP70-mediated procoagulant activity was absent in factor XII-deficient plasma. Collectively, we revealed that interaction between nSP70 and intrinsic coagulation factors such as factor XII, were deeply related to nSP70-induced harmful effects. In other words, it is suggested that if interaction between nSP70 and coagulation factors can be suppressed, nSP70-induced harmful effects may be avoided. These results would provide useful information for ensuring the safety of nanomaterials (NMs) and open new frontiers in biological fields by the use of NMs. 相似文献
135.
A method of carbon coating of silicon nanochains is developed for the controlled transformation of silicon nanochains into nanotubes of carbon: the surface of silicon nanochains is coated with hexadecanoic acid by annealing after plasma cleaning. Individual silicon nanochains are heated by applying an electric current using a micro-manipulator for the transformation. The transformation is observed in situ by means of transmission electron microscopy. 相似文献
136.
Sang-Hyun An Takuya Matsumoto Jun-Ichi Sasaki Hiroyuki Miyajima Ramaswamy Narayanan Satoshi Imazato Kyo-Han Kim 《Materials science & engineering. C, Materials for biological applications》2012,32(8):2516-2522
Anodization is an easily viable technique useful for producing TiO2 coatings on titanium substrates. Nano-crystalline anodic TiO2 structure was produced on titanium at 20 V using 1 M Na2SO4 and 0.5% NaF and consolidated by a further heat-treatment. Micro-crystalline anodic TiO2 was produced on titanium by applying a galvanostatic current density of 70 A/m2 in water medium. To assess the usefulness of these nano- and micro-oxides for bone implant stability, physical properties and bone in vitro bioactivity including HA formation, cellular affinity and mouse-tissue morphogenesis, were evaluated. Bioactivity of the different anodic surfaces was evaluated by treating them in a simulated body fluid (SBF) to form hydroxyapatite (HA) and the rates of HA formation were compared. Deposits of HA could be seen on the nano-oxide surface within 7 days, whereas HA was detected only after 14 days on the micro-oxide surface. In vitro cell culture tests done using mouse osteoblasts indicated that the nano-oxides showed statistically significant cell activity than the micro-oxides and the machined titanium. Branching morphogenesis test done for 72 h on these surfaces showed more branching on the micro- and nano-oxides as compared with titanium surface. 相似文献
137.
Momota S Zhang J Toyonaga T Terauchi H Maeda K Taniguchi J Hirao T Furuta M Kawaharamura T 《Journal of nanoscience and nanotechnology》2012,12(1):552-556
It has been found that ion implantation can induce a swelling (step-height) phenomenon on crystal surface. In this paper, we studied about the control of swelling height of Si crystal by irradiating Ar beam under various parameters (fluence, charge and energy). These irradiation parameters were regulated by an irradiation facility that enables to achieve the multiple ionization. For both charges, the swelling height was studied with the various fluencies of two different charges Ar(1+) and Ar(4+). The swelling height increased with increasing the fluence. The swelling height was also studied by changing energy of Ar(4+) beam. The swelling height increased by increasing the energy. The obtained swelling heights are understood base on the contribution of ion-beam induced defect, which is evaluated by SRIM. By comparing with the previous results, it was found that the expansion phenomena also depend on irradiated ion. The swelling structures were found to be stable more than two months. The present results have shown that this method of producing swelling structure indicates the potential application to fabricate 3-D nanostructure. 相似文献
138.
Ohya Y Miyoshi N Hashizume M Tamaki T Uehara T Shingubara S Kuzuya A 《Small (Weinheim an der Bergstrasse, Germany)》2012,8(15):2335-2340
Divalent DNA-AuNP (gold nanoparticle) conjugates comprising two DNA strands at diametrically opposed positions are prepared. Highly linear 1D and tetragonal lattice-like 2D AuNP arrays are constructed using the conjugates and DNA assemblies based on T- and double-crossover motifs and the Holliday junction. 相似文献
139.
Umemura K Noguchi Y Ichinose T Hirose Y Mayama S 《Journal of nanoscience and nanotechnology》2010,10(8):5220-5224
We investigated the morphology and physical-chemical properties of baked and unbaked nanoporous frustules. Scanning electron microscopy (SEM) observations showed that the nanoporous structures of frustules unchanged at 400 degrees C even after baking for 6 h. During baking at 800 degrees C, the frustule structures changed dramatically. On the other hand, Fourier transform infrared spectroscopy (FTIR) of bulk frustule samples indicated that physical-chemical properties of the frustules had clearly changed after baking at not only 800 degrees C but also 400 degrees C. These results showed that the reconstruction of the structures had occurred inside the frustules, even though the morphology of the frustules had not apparently changed at 400 degrees C. In order to characterize the exact shape of the frustules, living diatom cells were grown on a functionalized mica surface, and then baked without any chemical treatment for SEM study. This 'direct baking' technique is effective for comparing minute structures of the frustules, because completed combination of every part of the frustules can be observed. 相似文献
140.
Advenit Makaya Takuya Tamura Kenji Miwa 《Metallurgical and Materials Transactions A》2010,41(7):1646-1657
A process combining cooling slope casting and suction casting was developed to generate a semisolid structure in a Zr-based bulk metallic glass matrix composite. The melt was injected onto a cooling slope and subsequently vacuum sucked into a cylindrical copper mold placed at the end of the slope. The structure obtained for 4-mm-diameter specimens of composition Zr66.4Nb6.4Cu10.5Ni8.7Al8 consists of a dispersion of spheroidal and rosettelike bcc crystals in a glassy matrix. Various slope angles, slope lengths, and injection pressures were tested. The coarsest and most spheroidal crystal structure was obtained at short slope lengths and high injection pressures. Microstructure analysis suggests that the slope is the location of extensive crystal nucleation and possible fragmentation, while the microstructure’s morphological evolution seems to occur mainly in the mold. The semisolid structure is expected to confer improved mechanical properties and ductility to the composite material. 相似文献