Compound-specific chlorine isotope analysis: a comparison of gas chromatography/isotope ratio mass spectrometry and gas chromatography/quadrupole mass spectrometry methods in an interlaboratory study

Chlorine isotope analysis of chlorinated hydrocarbons like trichloroethylene (TCE) is of emerging demand because these species are important environmental pollutants. Continuous flow analysis of noncombusted TCE molecules, either by gas chromatography/isotope ratio mass spectrometry (GC/IRMS) or by GC/quadrupole mass spectrometry (GC/qMS), was recently brought forward as innovative analytical solution. Despite early implementations, a benchmark for routine applications has been missing. This study systematically compared the performance of GC/qMS versus GC/IRMS in six laboratories involving eight different instruments (GC/IRMS, Isoprime and Thermo MAT-253; GC/qMS, Agilent 5973N, two Agilent 5975C, two Thermo DSQII, and one Thermo DSQI). Calibrations of (37)Cl/(35)Cl instrument data against the international SMOC scale (Standard Mean Ocean Chloride) deviated between instruments and over time. Therefore, at least two calibration standards are required to obtain true differences between samples. Amount dependency of δ(37)Cl was pronounced for some instruments, but could be eliminated by corrections, or by adjusting amplitudes of standards and samples. Precision decreased in the order GC/IRMS (1σ ≈ 0.1‰), to GC/qMS (1σ ≈ 0.2-0.5‰ for Agilent GC/qMS and 1σ ≈ 0.2-0.9‰ for Thermo GC/qMS). Nonetheless, δ(37)Cl values between laboratories showed good agreement when the same external standards were used. These results lend confidence to the methods and may serve as a benchmark for future applications.     

Parallel kinematic concept for stationary high performance cutting in wood machining centers

In recent years parallel kinematic machines for wood machining have come into use more frequently. Despite first promising prototypes, these machines are single solutions for specific applications. To meet the requirements of shorter product life cycles and higher product diversity, high flexibility is demanded of the machining system. This paper presents a new wood machining center obtaining both, the reduction of the primary and secondary processing times. The machine concept, based on a parallel kinematic structure, allows high operating speeds and accelerations not only for workpiece machining but also for handling. Thus, the machine can be used without any external handling devices. The kinematic structure originates from a plane closed five-bar chain with two linear drives and additional drive axes for stroke and rotation. In order to increase the useable workspace a continuous motion between different assembly modes is realized. To guarantee a high feed rate and to minimize set-up times, an optimized dust exhaustion is included.     

Decentralized array processing using the MODE algorithm

Centralized methods for source location using sensor arrays have computational and communication burdens that increase significantly with the number of sensors in the array. Therefore, these methods may not be usable in the applications involving very large arrays. In such applications, the data processing may need to be decentralized. This paper introduces two methods for decentralized array processing, based on the recently proposed MODE algorithm. For prescribed nonoverlapping subarrays, both methods are shown to be statistically optimal in the sense that asymptotically they provide the most accurate decentralized estimates of source location parameters. The problem of subarray selection to further optimize the estimation accuracy is only briefly addressed. The two methods are intended for different types of applications: the first should be preferred when there exist significant possibilities for local processing or for parallel computation in the central processor; otherwise the second method should be preferred. The accuracy of the two decentralized methods is compared to the centralized Cramér-Rao bound, both analytically and numerically, in order to provide indications about the loss of accuracy associated with decentralized processing.The work of P. Stoica was supported by a grant from the Royal Swedish Academy of Engineering Sciences and by the Swedish Research Council for Engineering Sciences under contract 91-676. The work of A. Nehorai was supported by the Air Force Office of Scientific Research under grant no. AFOSR-90-0164, and by the Office of Naval Research under grant no. N00014-91-J-1298.on leave at the Department of Applied Electronics, Chalmens University of Technology, 2-41296 Göthensberg, Sweeden.     

Rekonstruktion von Barockspiegeln des Historischen Grünen Gewölbes im Dresdener Schloss

Reconstruction of Baroque Mirrors of the Historical Green Vault in the Dresden Royal Palace On the 1^st September 2006 the Federal Chancellor Dr. Angela Merkel inaugurated the reconstructed Historical Green Vault, the treasury museum of the Saxon electors and kings. Since its destruction on 13^th February 1945 two generations have been working scientific‐artistically in order to set the course for its reconstruction. The idea of a baroque mirror chamber has firstly been implemented on a sequence of 8 rooms in the Green Vault. The original mirrors, which were covered with tin amalgam, had a considerably lower reflexivity modern day silver mirrors. From originally 423 m² mirror surface, only 60 m² could be reused. For the restoration and reconstruction of the original mirrors extensive analytic investigations became necessary, which the state‐owned company Sächsisches Immobilien‐ und Baumanagement (SIB) commissioned the Fraunhofer Institute for Electron Beam and Plasma Technology (FEP). On basis of these results the responsible restoration commission decided to replace partly destroyed mirror surfaces using the historical tin amalgam mirror technology. The fully destroyed jewel room would be restored with mirrors including partial gold etching. Due to hygienical and temporal reasons those mirrors were coated through a mercury‐free vacuum thin film technology ‐ the magnetron sputtering. The results show that a layer system consisting of tin‐bronze‐titanium and protective lacquers represent an adequate replacement for the original tin amalgam mirrors. The procedure allows relatively uncomplicated partial silverings and a subsequent inserting of artistic gold etchings.     

Evidence for an intramedullary prostaglandin-dependent mechanism in the activation of stress-related neuroendocrine circuitry by intravenous interleukin-1

We have provided evidence that the stimulatory effects of intravenous interleukin-1 (IL-1) on neurosecretory neurons in the paraventricular nucleus (PVH) that express corticotropin-releasing factor (CRF) depend specifically on the integrity of catecholaminergic projections originating in caudal medulla. Here we report on experiments designed to test alternative means by which circulating IL-1 might access medullary aminergic neurons, including mechanisms involving sensory components of the vagus, the area postrema, or perivascular cells bearing IL-1 receptors. Neither abdominal vagotomy nor area postrema lesions reliably altered Fos expression induced in the medulla or PVH in response to a moderately suprathreshold dose of IL-1beta. Cytokine-stimulated increases in CRF mRNA in the PVH were also unaffected by either ablation. By contrast, systemic administration of the cyclooxygenase inhibitor indomethacin resulted in parallel dose-related attenuations of IL-1 effects in hypothalamus and medulla. Microinjections of prostaglandin E2 (PGE2; >/=10 ng) in rostral ventrolateral medulla, the principal seat of IL-1-sensitive neurons that project to the PVH, provoked discrete patterns of cellular activation in hypothalamus and medulla that mimicked those seen in response to intravenous IL-1. We interpret these findings as supporting the hypothesis that paracrine effects of PGE2 released from perivascular cells in the medulla as a consequence of IL-1 stimulation and, acting through prostanoid receptors on or near local aminergic neurons that project to the PVH, contribute to the stimulatory effects of increased circulating IL-1 on neurons constituting the central limb of the hypothalamo-pituitary-adrenal axis.     

Communication requirements - basis for investment in a utility wide-area network

This paper addresses the various requirements forming the basis for investing in a utility wide-area network (WAN). One single requirement cannot itself motivate the total cost of a WAN, whereas the requirements altogether could do that. The paper is based on experiences from Svenska Kraftna/spl uml/t (Swedish National Grid). The presentation aims to be comprehensive, and it should provide support when a utility WAN is to be planned. The contribution of the paper is to provide engineering perspectives on the requirements, rather than a pure theoretical view.