工业建筑多层框架的活荷载不利布置

以设防烈度为8度的框架厂房为例，详细分析了活荷载不利布置对框架梁、柱内力的影响，得出何时需要考虑活荷载不利布置、何时不需要考虑活荷载不利布置的结论，可供工程设计参考。     

纵横波测井资料在储层评价中的应用

将弹性波基础理论，Gasman理论，Biot理论和实验研究结果相结合，探讨了沉积岩地层中速度和弹性模量，弹性模量和孔隙度，剪切模量和孔隙度，速度和孔隙度，孔隙度和Biot系数之间的关系，利用从各种声学测井资料中提取出的P波和S波时差（或速度）定量评价地层孔隙度和骨架物质，辅以泥质指示测井曲线，可以计算地层孔隙度，饱和度，岩性等参数，在M，Krief方法的基础上，采用优化算法寻求适合于任何岩性地层的孔隙度与Biot系数之间的关系式，提高了Biot系数的计算精度，该评价方法有坚实的实验基础和理论基础，评价结果与实验室岩心分析数据吻合。     

大港白水头地区低阻油气层测井评价

在对白水头地区低阻油层的地质特征、物性特征及成因环境进行了分析研究后 ,应用测井曲线特征集法 ,把白水头油田常规油气层、低阻油气层、油水同层、水层等看成是独立的地质事件 ,建立了它们与测井曲线特征之间的对应关系 ,利用这种关系对未知地质事件进行了预测划分。最后根据所建模型定量计算储层各种参数 ,收到了良好的地质效果 ,表明测井曲线特征集法对于识别多成因的低阻油层是一种有效方法     

Automatic conversion from lexical words to prosodic words for mandarin text-to-speech system

In real speech, not like lexical words (LWs), prosodic words (PWs) are basic rhythmic units. The naturalness of a Text-to-Speech (TTS) system is directly influenced by the segmentation of the PWs. Most of the PWs are the combination of several LWs. In this paper, three Lexical Combination Models are proposed to combine LWs into PWs, including a Directed Acyclic Graph Model, a Segmentation Model and a Markov Model (MM). To cope with the situation where some long LWs should be segmented into two or more PWs, a Lexical Split Model (LSM) is applied to the long LWs. Experimental results prove that relatively constant results with various training data can be obtained from a MM. The Transformation-Based Error Driven Learning (TBED) algorithm, for its high performance of individual property, is applied in combination with the MM to improve the precision of PW segmentation. Experiments show that among the three proposed models, the MM combined with TBED and LSM, leads to the best performance, in which a precision of 93.00% and a recall of 93.23% are achieved. The perception test indicates that by using PWs as the lowest prosodic units a speech sounds more natural and acceptable than by using LWs. This paper is supported by NSFC Project (60503071); 973 Natural Basic Research Program of China (2004CB318102); Postdoctor Science Foundation of P. R. China (20070420275).     

主跨348m+348m三塔单索面PC梁斜拉桥

宜昌市夷陵长江大桥采用三塔斜拉桥，总体布置为(128．08 348 348 120．35)m。介绍了该桥的合理性及结构特点。     

温度应力、自收缩对高性能混凝土早期开裂的影响

根据高性混凝土的水化特性、物理力学特性及自收缩特性，分析了高性能混凝土早期开裂机理和影响早期开裂的主要因素．并结合工程实例，借助混凝土温度和应力有限元仿真计算方法分析研究了表面适度保温和水管冷却技术在高性能混凝土温控防裂中的应用效果．研究结果表明，表面适度保温与水管冷却相结合能有效降低混凝土的内外温差，减小混凝土早期表面拉应力与后期内部拉应力，防裂效果明显，对类似的工程具有借鉴作用．     

基坑工程雨季施工措施的探讨

结合某校教学楼基坑工程实践，对防止滑坡采取措施的有效性进行了总结，同时对滑坡出现的原因进行分析，提出了预防基坑滑坡应注意事项。     

Strengthening of Preloaded RC Beams Using Hybrid Carbon Sheets

Reinforced concrete (RC) beams subject to service loads of 40 or 60% of steel yielding were strengthened using hybrid continuous carbon fiber sheets. The hybrid systems were made of high-strength and high-modulus carbon sheets, and compared with systems using only high-strength carbon. It was found that the use of high-modulus carbon sheets in hybrid systems could increase the yielding load, the flexural stiffness, the postyielding ductility, and reduce the crack opening in concrete. The slope changes on load-deflection curves at steel yielding are not noticeable in hybrid systems. The tensile strains developed in hybrid sheets after the fracture of high-modulus carbon are higher in magnitude and distributed in a larger area, leading to an ultimate carbon fracture with concrete crushing. These unique features are attributed to the high stiffness and low ultimate tensile strain of the high-modulus carbon fibers which stiffen the structures, avoid or delay the fiber-reinforced polymer debonding, and facilitate the deformability during their subsequent breakdown.     

模糊环境的表示及机器人轨迹规划

本文利用模糊集理论，提出一种非确定环境的描述方法，并且针对机器人在该类环境中的避障轨迹规划，建立了相应的决策函数和规划策略，最后，给出在ＰＣ－３８６计算机上的仿真试验结果。     

7-Hydroxystaurosporine (UCN-01) induces apoptosis in human colon carcinoma and leukemia cells independently of p53

7-hydroxystaurosporine (UCN-01) is a more selective protein kinase C inhibitor than staurosporine. UCN-01 exhibits antitumor activity in experimental tumor models and is presently in clinical trials. Our study reveals that human myeloblastic leukemia HL60 and K562 and colon carcinoma HT29 cells undergo internucleosomal DNA fragmentation and morphological changes characteristic of apoptosis after UCN-01 treatment. These three cell lines lack functional p53, and K562 and HT29 cells are usually resistant to apoptosis. DNA fragmentation in HT29 and K562 cells occurred after 1 day of treatment while it took less than 4 h in HL60 cells. Cycloheximide prevented UCN-01-induced DNA fragmentation in HT-29 cells, but not in HL60 and K562 cells, suggesting that macromolecular synthesis is selectively required for apoptotic DNA fragmentation in HT29 cells. UCN-01-induced DNA fragmentation was preceded by activation of cyclin B1/cdc2 kinase. Further studies in HL60 cells showed that UCN-01-induced apoptosis was associated with degradation of CPP32, PARP, and lamin B and that the inhibitor of caspases (ICE/CED-3 cysteine proteases), Z-VAD-FMK, and the serine protease inhibitor, DCI, protected HL60 cells from UCN-01-induced DNA fragmentation. However, only DCI and TPCK, but not Z-VAD-FMK, inhibited DNA fragmentation in the HL60 cell-free system, suggesting that serine protease(s) may play a role in the execution phase of apoptosis in HL60 cells treated with UCN-01. Z-VAD-FMK and DCI also inhibited apoptosis in HT29 cells. These data demonstrate that the protein kinase C inhibitor and antitumor agent, UCN-01 is a potent apoptosis inducer in cell lines that are usually resistant to apoptosis and lack p53 and that caspases and probably serine proteases are activated during UCN-01-induced apoptosis.