Measurement and Correlation for Solubility of (S)-(+)-2,2-Dimethyl-cyclopropane Carbox Amide in Different Solvents

1 INTRODUCTION (S)-(+)-2,2-dimethylcyclopropane carbox amide [(+)-DMCPCA, Fig.1] is a key intermediate of Cilas- tatin, an inhibitor of dehydropeptidase-I. As the syner- gist of imipenem (an antibiotic drug), cilastatin is widely used in clinical applications and has prosper- ous prospects[1]. In industrial manufacture[2―6], as the optical intermediate, the chemical and optical purity of (+)-DMCPCA would affect the quality of cilastatin. So, the separation and purification are impo…     

钢渣细度对水泥混凝土物理力学性能影响

研究了钢渣细度对混凝土力学性能和安定性的影响 ,探讨了影响机理。实验表明 ,用钢渣等量替代部分水泥时 ,混凝土强度随钢渣细度增加而提高 ,特别在钢渣掺量小于 2 0 %时 ,强度增长更明显 ;实验所用各细度钢渣微粉的安定性能均满足要求。     

科学管理确保乙烯装置长周期稳定运行

针对乙烯装置长周期运行面临的问题，中国石油独山子石化分公司乙烯厂采用科学的管理手段和技术进步措施，确保装置长周期运行。     

密螺旋体Reiter株轴丝的提纯及鉴定

将Reiter株菌体超声破碎,上清液经离子交换柱层析及凝胶过滤,得到纯化轴丝。该轴丝经SDS—PAGE检测分析,所得结果与丹麦参考品一致,分子量在3～4万之间,与文献报道相同。经电镜观察,产物均匀,未被杂质污染。按上述方法提取,3克湿重菌体最终可得2毫克左右轴丝蛋白。     

An Investigation of Error Sources in Computational Fluid Dynamics Modelling of a Co-current Spray Dryer

The paper is focused on identifying error sources in computational fluid dynamics(CFD) predictions of a spray drying process. Seven groups of drying and atomisation parameters were selected for analysis and 13 simulation trials were performed. The theoretical results were compared with experimental data and sensitivity of the simulation results to the analysed factors was determined. The following parameters affecting the accuracy of CFD spray modelling were found: gas turbulence model, particle dispersion, atomising air, initial parameters of atomisation and heat losses to the environment. A major difference in the errors committed during modelling of spray drying process for fine and coarse sprays was observed.     

丙烯酸酯乳液的改性研究

制备了丙烯酸酯乳液,探讨了丙烯酸、N-羟甲基丙烯酰胺、二乙烯基苯、丙烯腈和三聚氰胺等不同改性剂对乳液性能的影响,在此基础上通过互穿网络聚合、化学共聚及物理共混等方法对乳液的性能进行了改性研究。     

新型液压胀合有缝不锈钢管衬里复合管的制造技术

针对目前液压生产复合管方法的不足，研制开发了一种新型不锈钢衬里复合管液压胀合装置。介绍了该装置的工作原理和结构特点及液压胀合复合管的制造技术。     

汽车外塑料部件均应用现状及趋势

生产轿车外表部件朝着质轻、高强度、易回收、成本更低的方向发展,塑料是首选材料,显示出极大的优势,预计在未来十年内,轿车外部板件生产将全面采用塑料制板件,取代钢制板件。     

氯化锂－水吸附式再循环型空调制冷系统性能研究

对氯化锂－水吸附式空调系统在再循环运行方式下的性能进行了模拟。分析了再生温度、热交换器效率及蒸发冷却器效率对性能的影响。与开式通风型空调制冷系统的制冷性能相比，再循环型空调制冷系统的制冷能力较大，但性能系数ＣＯＰ较小     

应用免疫印迹法分析丙型肝炎相关性抗体

应用两种免疫印迹法对二代ELISA测试的69份血清进行了追加试验。结果表明:8份ELISA阴性血清免疫印迹均阴性,61份ELISA阳性血清有1份免疫印迹阴性。ELISA假阳性率为1.67％。在60份免疫印迹阳性血清中,抗结构区(capsid),非结构区NS_3和NS_4抗体的阳性率分别为83％、93.3％和70％。其中丙型肝炎相关性抗体的分布,以抗capsid、NS_3、NS_4抗体都阳性为主(58.7％)。在输血后急性肝炎和肝细胞癌患者中。丙型肝炎相关性抗体的分布没有统计学上的差异。