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11.
Abstract:  This study proposes an alternate method for the analysis of beams with solid cross-section or built as a framed structure and subjected to transverse impact loads from an external striker. The procedure used in the analysis is a combination of two essential tools using pseudo-dynamic techniques. The method reported here involves only one degree of freedom for the structure modelling and assumes an elastic contact between an external striker and the beam structure, which in reality does not happen. As only one degree of freedom is considered in the analysis, some important limitations are inherent to the method proposed here. Essentially, there is the difficulty of modelling the displacement field associated with the transient structure behaviour accurately, as a consequence of fast-rate impact loads. Another difficulty faced by the method refers to a local structure behaviour associated with contact loads. The present method can deal with large displacements in transversely loaded beams associated to a collapse mechanism having a simple geometry and defined with precision from a single parameter. This ensures reasonable accuracy in the evaluation of the strain energy absorbing capacity of transversely impacted beam structures using a single degree of freedom model in a pseudo-dynamic procedure.  相似文献   
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The adaptation of software components developed for a specific application in order to generate reusable components often includes some kind of generalization. This generalization may be carried out, for instance, by the renaming of some identifiers or by its parameterization. In our work, we are specially interested in the generalization by parameterization of algebraic specification components. Generalization and some other transformations on algebraic specifications are being integrated in the FERUS tool. This tool was initially developed for the Common Algebraic Specification Language, called CASL, and we show in the paper its adaptation to the new version of the rule-based programming language ELAN.  相似文献   
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To estimate the prevalence of both clinically evident and asymptomatic carriage of fluconazole-resistant Candida, we prospectively surveyed 128 adults infected with human immunodeficiency virus (HIV). The patients had an average CD4 cell count of 206/mm3. Ninety-seven isolates of Candida were obtained from the oropharynx of 82 patients (64%). Of these 82 patients, 76% carried C. albicans alone; 18%, both albicans and non-albicans isolates; and 6%, non-albicans species alone. Oropharyngeal candidiasis was evident in only 38 (46%) of the 82 patients for whom a culture was positive and was never seen unless C. albicans was present. When MICs were measured by using the National Committee for Clinical Laboratory Standards M27-T methodology and grouped by using recently proposed breakpoints, we found that eight of the 38 patients with oropharyngeal candidiasis and six of the 44 patients who were asymptomatically colonized carried C. albicans isolates resistant to fluconazole (MIC, > or = 64 micrograms/mL); estimated rates of carriage were 21% (95% confidence interval, 10%-37%) and 14% (95% confidence interval, 5%-27%), respectively. Carriage of resistant isolates of C. albicans by HIV-infected adults is more common than previously suspected, and clinicians should be alert to the possible need for either higher doses of fluconazole or alternative treatment modalities.  相似文献   
14.
The confinement of concrete columns provided by carbon fibre reinforced plastic (CFRP) sheets can be an efficient technique for their structural strengthening. The principal advantages of this technique are the high strength-to-weight ratio, good fatigue properties, non-corroding characteristics of the CFRP, and the facility of its application. An experimental research program, that included tests on 54 short column specimens, was carried out to investigate the gain in strength and ductility of concrete columns externally confined by CFRP wrapping. The variables studied were the column cross section shape (circular, square and rectangular) and the amount of confinement expressed in the number of CFRP sheet layers applied to the models (one or two layers). On the basis of the obtained results, equations were proposed to calculate the confined concrete strength and the ultimate confined concrete strain as a function of the confining lateral stress for each of the cross section geometry used, circular, square and rectangular. The estimations given by these equations and by those from formulas encountered in the literature were compared with the experimental ones and general conclusions were, finally, drawn.
Résumé Le confinement de colonnes de béton assuré par des feuilles de plastique renforcé par des fibres de carbone (CFRP) peut être une technique efficace pour leur comportement structural. Les principaux avantages de cette technique sont la haute relation résistance-poids, des bonnes propriétés de fatigue, les caractéristiques non-corrosives du CFRP, et la facilité de leur application. Un programme expérimental comprenant des essais sur 54 colonnes courtes fut entrepris en vue de déterminer le gain de résistance et de ductilité de colonnes en béton confinées sur le plan externe en les recouvrant de feuilles de CFRP. Les variables étudiées étaient la forme de la section transversale (circulaire, carrée et rectangulaire), et la quantité de renforcement, mesurée par le nombre de feuilles de CFRP appliquées aux modèles (une ou deux couches). En prenant comme base les résultats obtenus, des équations ont été proposées pour calculer la résistance du béton confiné et sa déformation spécifique ultime en fonction de la contrainte latérale de confinement, pour chaque forme de section transversale utilisée, circulaire, carrée et rectangulaire. Les estimations données par ces équations et celles données par des formules trouvées dans la litérature ont été comparées avec les résultats expérimentaux et des conclusions générales ont finalement été établies.
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This paper starts with a review of the prevailing channel-selection techniques utilized so far in the design of wireless transceiver analog front-ends before describing a novel two-step channel-selection technique, which handles the traditionally unwanted image, in radio frequency-to-intermediate frequency (RF-to-IF) or IF-to-RF frequency conversion, as a useful adjacent channel of the desired one, and selects deliberately either of them from IF to baseband (or baseband to IF). Thus, one more channel-selection possibility is created for both low-IF receivers and two-step-up transmitters. The consequential benefits of introducing channel selection at IF consist of two. First, many design specifications (such as phase noise and settling time) of the RF frequency synthesizer and local oscillator can be substantially relaxed. Second, a low-IF/zero-IF reconfigurable receiver and a direct-up/two-step-up reconfigurable transmitter can be synthesized to match better with narrowband-wideband-mixed multistandard systems. The operating principles of such architectures are presented in easy-to-understand complex-signal spectral-flow illustrations, and their practicability is demonstrated in the design of a Bluetooth/IEEE 802.11FH/HomeRF multistandard receiver. SPECTRE simulation results validate the reconfigurable functionalities mainly implemented by a triple-mode channel-select filter and a multifunctional sampling-mixer scheme.  相似文献   
19.
Physalis angulata L (Solanaceae) is a medicinal plant from North of Brazil, whose different extracts and infusions are commonly used in the popular medicine for the treatment of malaria, asthma, hepatitis, dermatitis and rheumatism. However, the genotoxic effects of P. angulata on human cells is not well known. The main purpose of the present study was to evaluate the in vitro genotoxic effects of aqueous extract of P. angulata using the comet assay and the micronucleus assay in human lymphocytes provided from 6 healthy donors. Treatments with P. angulata extracts were performed in vitro in order to access the extent of DNA damage. The comet assay has shown that treatments with P. angulata at 0.5, 1.0, 2.0, 3.0 and 6.0 microg/mL in culture medium were genotoxic. Lymphocytes treated with P. angulata at the concentrations of 3.0 and 6.0 microg/mL in culture medium showed a statistically significant increase in the frequency of micronucleus (p<0.05), however, the cytokinesis blocked proliferation index (CBPI) was not decreased after P. angulata treatment. In conclusion, the present work demonstrated the genotoxic effects of P. angulata extract on human lymphocytes in vitro.  相似文献   
20.
Streptococcus bovis bacteremia is known to be related to neoplastic lesions of the colon. We describe a patient with several complications of S bovis bacteremia and adenocarcinoma of the colon--endocarditis, spondylodiskitis, and splenic abscess. We believe this is the eighth known case of endocarditis and diskitis caused by S bovis and the third case of endocarditis and splenic abscess by S bovis in a patient with adenocarcinoma of the colon.  相似文献   
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