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81.
The overlapping of activities is a common practice to accelerate the execution of engineering projects. This technique consists in executing in parallel two activities, normally executed in a sequential way, by allowing the downstream activity to start before the end of the upstream activity based on preliminary information. In this paper, we propose a constructive heuristic for the resource-constrained project scheduling problem with overlapping modes (RCPSP-OM). Given a set of activities to execute, the RCPSP-OM consists in determining the order of execution in time of a set of activities so as to minimize the total project duration, while respecting precedence relations, resource constraints and overlapping possibilities. The heuristic implies that rework tasks related to overlapping are added to downstream activities and that the consumption of the resources is constant throughout the execution of the project (including rework). The method also considers that the possible overlapping modes for every couple of activities and the duration of rework tasks associated with every mode are known in advance. Results show that, when the objective consists in minimizing the project duration, the consideration of the costs associated to activity overlapping allows to significantly reducing the cost of reworks. On the other hand, when the objective consists in maximizing the gains related to the project execution, the search for the best trade-off between acceleration and increase of project costs enables to avoid losses.  相似文献   
82.
In Brazil, the National Council for Scientific and Technological Development (CNPq) distributes productivity fellowships in research (RS) as a recognition to individuals with outstanding productivity levels in their areas. The aim of this study is to evaluate the scientific production of the Brazilian Pharmacy area, one division of the Health Sciences Great Area of CNPq, considering the profile and productivity levels of RS fellows. The results showed that most of the 156 active RS fellows in 2015 were female, with doctorate completed in the Southeast region (mainly in University of São Paulo) and with research activities developed in the South and Southeast regions. Most of their work was published in journals classified as B1 and B2 Qualis in Pharmacy by the Coordination for the Improvement of Higher Education Personnel (CAPES), with high prevalence of publications in local journals and/or specialized on medicinal plants. Besides, they featured much dependence on advising and productivity indexes related to the category and level of RS fellowship. The evolution of such data must be continually evaluated to determine the influence of CNPq productivity fellowships on performance and stratification of researchers in the Pharmacy area in Brazil.  相似文献   
83.
84.
The passive fit between prosthesis and implant is a relevant factor for screw joint stability and treatment success. The aim of this study was to evaluate the influence of vertical misfit in abutment-implant interface on preload maintenance of retention screw of implant-supported crowns. The crowns were fabricated with different abutments and veneering materials and divided into 5 groups (n = 12): Gold UCLA abutments cast in gold alloy veneered with ceramic (Group I) and resin (Group II), UCLA abutments cast in titanium veneered with ceramic (Group III) and resin (Group IV), and zirconia abutments with ceramic veneering (Group V). The crowns were attached to implants by gold retention screws with 35-N cm insertion torque. Specimens were submitted to mechanical cycling up to 106 cycles. Measurements of detorque and vertical misfit in abutment-implant interface were performed before and after mechanical cycling. ANOVA revealed statistically significant difference (P < 0.05) among groups for vertical misfit measured before and after mechanical cycling. The abutments cast in titanium exhibited the highest misfit values. Pearson correlation test did not demonstrate significant correlation (P > 0.05) between vertical misfit and detorque value. It was concluded that vertical misfit did not influence torque maintenance and the abutments cast in titanium exhibited the highest misfit values.  相似文献   
85.
Biohydrogen (bioH2) production via dark fermentation is an attractive approach to overcome the drawbacks of conventional hydrogen production methods and represents a preliminary alternative for the management of organic wastes. Fundamental studies are still required to enhance the performance of bioH2 production systems, with emphasis on the development of novel reactor configurations. The anaerobic structured-bed reactor (ASTBR) is a recently developed configuration with great potential for bioH2 production, although operating strategies are still required to minimize biomass washout in such systems. In this context, calcium dosing has been investigated as a strategy to enhance both biomass retention and bioH2 production rates in the ASTBR. The present study employed varying COD/calcium ratios (4423, 2079, 1357, 1012, 884, and 632) in continuous experiments under mesophilic conditions (25 °C). Calcium dosing effectively enhanced biomass retention within the ASTBR, directly increasing the availability of metabolic energy for different metabolic pathways rather than cell synthesis. An optimal COD/calcium ratio of 1360 was mathematically estimated for bioH2 production, which is consistent with the results obtained experimentally. The specific organic loading rate (SOLR) was better controlled at this ratio, indicating the establishment of balanced conditions in terms of substrate availability and biomass concentration. Conversely, bioH2 production was severely impaired at COD/calcium values below and above the optimal range, most likely due to enhancement of the homoacetogenic pathway as a result of unbalanced conditions in the SOLR. Furthermore, biomass accumulation did not strongly affect the mean residence time of the ASTBR, facilitating its robust and enhanced solid retention.  相似文献   
86.
This paper discusses the identification of parameters in rotary systems, namely, the unbalance magnitude, phase and position in the rotor system. These parameters can be identified using the measured orbits in the hydrodynamic bearings. The oil film forces are evaluated in the different positions of the orbit of the journal and are applied to the model of the shaft. The model, integrated in time domain, allows with an assumed unbalance, to simulate the orbits. The objective function is basically the difference between measured and simulated orbits, and its minimum corresponds to the identified unbalance amount, phase and position along the shaft. With respect to traditional model based identification procedures, this approach using oil film forces instead of oil film linearized stiffness and damping coefficients, and unfiltered orbits instead of 1X vibration components is suitable to deal with non-linear behaviour of the system.  相似文献   
87.
In recent years, the use of hip prostheses has become a routine procedure. The use of total hip replacement has evolved in recent years to a routine procedure. Despite this experience, it always comes back to complications. Especially the migration or loosening of the acetabular component because of the artificial load adaptive bone remodeling is still a current problem. This is due to the changing mechanical situation after the implantation of the prosthesis. Another problem is the high bone loss during implantation, which complicates a revision of the prosthesis. One solution is the use of patient‐specific prostheses. So far, the use of these prostheses is limited due to the time‐consuming and cost‐intensive production. The overall objective of the presented project in this publication is the development and establishment of an innovative concept for the production of patient‐specific hip prosthesis made of titanium plates by sheet metal forming. The idea of this concept involves the development of a two‐stage process. First of all a standardized hip prosthesis is made by high‐pressure sheet metal forming and then individually in the second step. This publication contains the derivation of the standard prosthesis. For this purpose, a design methodology was generated, based on the so‐called agglomerative clustering. In addition, presents the results of the numerical preliminary design of the first stage of the process and the tool developed concept in the course of this paper.  相似文献   
88.
A two dimensional model of bread baking was developed including, for the first time, the dependence of dough viscosity on both temperature and moisture content, the carbon dioxide dissolved from liquid water together with gas generation from yeast at the beginning of baking and the shrinkage due to dough drying. Particular attention was paid to experimental validation of both overall and local variables such as local temperature, overall mass loss, and local moisture content, overall CO2 released into the oven, and overall deformation and local expansion or shrinkage. Sensitivity studies on generation of carbon dioxide, gravity, and shrinkage are presented to discuss their influences on bread geometry, porosity (reflecting the alveolar structure) and gas pressure. © 2016 American Institute of Chemical Engineers AIChE J, 62: 3847–3863, 2016  相似文献   
89.
Montmorency sour cherry (Prunus cerasus L.) pit oil (CPO) was extracted and characterized by various methods including: GC, LC–MS, NMR, thermogravimetric analysis (TGA), differential scanning calorimetry (DSC) and X‐ray powder diffraction (XRD). The oil gave an acid value of 1.45 mg KOH/g, saponification value of 193 mg KOH/g and unsaponifiable matter content of 0.72 %. The oil contained oleic (O) and linoleic (l ) acids as the major components with small concentrations of α‐eleostearic acid (El, 9Z,11E,13E‐octadecatrienoic acid) and saturated fatty acid palmitic (P) acid. The CPO contained six major triacyglycerols (TAG), OOO (16.83 %), OLO (16.64 %), LLO (13.20 %), OLP (7.25 %), OOP (6.49 %) and LElL (6.16 %) plus a number of other minor TAG. The TAG containing at least one saturated fatty acid constitute 33 % of the total. The polymorphic behavior of CPO as studied by DSC and XRD confirmed the presence of α, β′ and β crystal forms. The oxidative induction time of CPO was 30.3 min at 130 °C and the thermal decomposition temperature was 352 °C.  相似文献   
90.
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