基于MFA-ICA的间歇过程在线监控

针对间歇过程独特的数据特点,提出1种将因子分析(FA)作为独立成分分析(ICA)白化预处理手段的多向因子分析白化独立成分分析(multiway factor analysis-independent component analysis,MFA-ICA)间歇过程监控方法.因子分析充分考虑了模型误差的普遍意义,拥有优秀的噪声建模能力.将其代替上成分分析用于白化,可以更好的提取数据集的本质信息.首先将间歇过程三维数据依次按批次和变量展开得到二维数据矩阵,接着把上述方法用于展开后的数据,利用ICA的,I2统计图实现在线故障检测.该方法用于标准仿真平台Pensim,结果表明上述方法对于提高间歇过程故障检测的快速性,降低漏报率有明显效果.     

KISTCM: knowledge discovery system for traditional Chinese medicine

Objective: Traditional Chinese Medicine (TCM) provides an alternative method for achieving and maintaining good health. Due to the increasing prevalence of TCM and the large volume of TCM data accumulated though thousands of years, there is an urgent need to efficiently and effectively explore this information and its hidden rules with knowledge discovery in database (KDD) techniques. This paper describes the design and development of a knowledge discovery system for TCM as well as the newly proposed KDD techniques integrated in this system.     

Interactive visualization of hyperspectral images of historical documents

This paper presents an interactive visualization tool to study and analyze hyperspectral images (HSI) of historical documents. This work is part of a collaborative effort with the Nationaal Archief of the Netherlands (NAN) and Art Innovation, a manufacturer of hyperspectral imaging hardware designed for old and fragile documents. The NAN is actively capturing HSI of historical documents for use in a variety of tasks related to the analysis and management of archival collections, from ink and paper analysis to monitoring the effects of environmental aging. To assist their work, we have developed a comprehensive visualization tool that offers an assortment of visualization and analysis methods, including interactive spectral selection, spectral similarity analysis, time-varying data analysis and visualization, and selective spectral band fusion. This paper describes our visualization software and how it is used to facilitate the tasks needed by our collaborators. Evaluation feedback from our collaborators on how this tool benefits their work is included.     

飞机结构总体优化设计方法

优化设计可以改善结构的应力分布,合理布置材料,从而提高材料的利用率.通过对全机结构逐层分解,确定优化设计变量、优化区域以及响应约束,并应用MSC Nastran中的可行方向法和敏度分析方法,对MA700飞机的机翼进行优化设计方法研究,考虑稳定性因素,初步解决长桁尺寸确定的问题,为后续优化设计工作积累经验.     

小子样状态下舰船特种阀门可靠性评估方法

针对舰船特种阀门 可靠性评估比较困难的问题,提出了将Bayes理论和相似性理论相结合的评估新方法.充分利用历史先验信息,并结合现场数据从而获得后验分布;利用相似性理论确定新旧型号阀门的相似度精确值.综合历史后验和后验分布,得到产品可靠性的融合后验.结合实例,对比分析了经典评估方法、传统Bayes方法和新方法所得到的新型号特种阀门可靠性的置信下限,验证了所提出方法的科学性和实用性.研究了新型号阀门的两参数威布尔寿命分布特性,给出了可靠度函数和可靠度寿命表达式,其计算结果可作为产品的接收判据,并在应用中提高了舰船特种阀门可靠性的评估精度,同时可以显著地减少现场试验样本数量.     

检测未知网络攻击的蜜罐系统

Internet的迅速发展使网络信息安全问题变得日益突出。分析了蜜罐技术，提出了使用蜜罐技术检测、分析新的、未知的网络攻击的思想并进行了设计和实现。     

Na99TcmO4示踪显像监测家兔断肢再植术后血管危象的对比研究

将40只家兔施行断肢再植术后20min随机分为A(25只)、B(15只)两组,A组伤口局部冷敷(<5°C)、B组热敷(40—45°C)10min,C组(5只正常对照家兔)置于室温(20—25°C)。所有家兔耳缘静脉注射Na99TcmO474MBq后行动态和静态显像,计算并分析再植部分和正常肢对应部分的放射性摄取比值(T/NT)。手术探查再植肢是否并发血管危象(VC)。根据术肢远端放射性聚集程度将显像结果分为Ο、Ⅰ、Ⅱ三级,结果显示:T/NT分别为0.142±0.061、0.472±0.055、0.843±0.184(t=7.23、13.65、2.71,P<0.01),将Ο级(T/NT<0.25)作为VC的定性和半定量诊断标准。手术探查证实A、B、C三组分别有25只、3只、0只家兔并发VC,局部冷敷制备VC动物模型的成功率100%;Na99TcmO4示踪显像(Na99TcmO4traceimaging,TTI)诊断VC的灵敏度(96.4%),明显高于临床常规方法(Clinicalroutinemethod,CRM)(39.3%)(χ2=20.9,P<0.01)。表明TTI较CRM更能直观而准确地反映再植末端的血供状况,能早期无创地监测断肢(指)再植术后VC的发生。     

基于Fluent的熔融金属填充焊接冲蚀孔形成过程数值模拟

针对熔融金属填充焊接工艺过程中液流冲蚀形成小孔的过程进行数值模拟研究. 分析确定该过程的控制方程和边界条件,建立二维轴对称模型. 利用Fluent软件,从物理过程出发建立凝固熔化模型以及热源模型. 利用VOF模型追踪金属相与气相界面,获得液流在不同的焊接条件下,冲蚀形成小孔的过程. 并通过获得的流场,温度场分析形成不同形貌小孔的原因. 利用锡铅合金为试验材料在堆焊过程中得到的焊缝截面形貌,试验结果表明,模拟计算得到结果与试验结果基本吻合.     

Combining magnetic nanoparticle with biotinylated nanobodies for rapid and sensitive detection of influenza H3N2

Our objective is to develop a rapid and sensitive assay based on magnetic beads to detect the concentration of influenza H3N2. The possibility of using variable domain heavy-chain antibodies (nanobody) as diagnostic tools for influenza H3N2 was investigated. A healthy camel was immunized with inactivated influenza H3N2. A nanobody library of 8 × 10⁸ clones was constructed and phage displayed. After three successive biopanning steps, H3N2-specific nanobodies were successfully isolated, expressed in Escherichia coli, and purified. Sequence analysis of the nanobodies revealed that we possessed four classes of nanobodies against H3N2. Two nanobodies were further used to prepare our rapid diagnostic kit. Biotinylated nanobody was effectively immobilized onto the surface of streptavidin magnetic beads. The modified magnetic beads with nanobody capture specifically influenza H3N2 and can still be recognized by nanobodies conjugated to horseradish peroxidase (HRP) conjugates. Under optimized conditions, the present immunoassay exhibited a relatively high sensitive detection with a limit of 50 ng/mL. In conclusion, by combining magnetic beads with specific nanobodies, this assay provides a promising influenza detection assay to develop a potential rapid, sensitive, and low-cost diagnostic tool to screen for influenza infections.     

一起10kV干式铁心电抗器烧毁事故原因分析

结合10 k V干式电抗器的外部结构、运行环境、检查情况、后台保护信息等,对一起干式电抗器烧毁事故进行了分析,发现电容器组频繁的投切使系统产生操作过电压,诱使电抗器绕组末端与铜排连接不良处产生大电流、局部放电,最终导致电抗器烧毁,并有针对性地提出防范措施,确保其稳定运行。