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101.
The paper research is concerned with enabling parallel, high-performance computation—in particular development of scientific software in the network-aware programming language, Java. Traditionally, this kind of computing was done in Fortran. Arguably, Fortran is becoming a marginalized language, with limited economic incentive for vendors to produce modern development environments, optimizing compilers for new hardware, or other kinds of associated software expected of by today’s programmers. Hence, Java looks like a very promising alternative for the future. The paper will discuss in detail a particular environment called HPJava. HPJava is the environment for parallel programming—especially data-parallel scientific programming—in Java. Our HPJava is based around a small set of language extensions designed to support parallel computation with distributed arrays, plus a set of communication libraries. A high-level communication API, Adlib, is developed as an application level communication library suitable for our HPJava. This communication library supports collective operations on distributed arrays. We include Java Object as one of the Adlib communication data types. So we fully support communication of intrinsic Java types, including primitive types, and Java object types.  相似文献   
102.
This article focuses on preteen British children's use of text messaging, particularly the abbreviations and characteristic language used within text messages. We look not only at the language style used by the children, but at the ways in which it relates to their traditional literacy skills, as measured through standardized tests and assessments. We have found repeated positive relationships between use of text register language and traditional literacy skills, and we give here a preview of our latest, longitudinal work, which allows those relationships to be studied directionally, enabling us to draw causal conclusions.  相似文献   
103.
Successful gradient-based sequential approximate optimization (SAO) algorithms in simulation-based optimization typically use convex separable approximations. Convex approximations may however not be very efficient if the true objective function and/or the constraints are concave. Using diagonal quadratic approximations, we show that non-convex approximations may indeed require significantly fewer iterations than their convex counterparts. The nonconvex subproblems are solved using an augmented Lagrangian (AL) strategy, rather than the Falk-dual, which is the norm in SAO based on convex subproblems. The results suggest that transformation of large-scale optimization problems with only a few constraints to a dual form via convexification need sometimes not be required, since this may equally well be done using an AL formulation.  相似文献   
104.
Kidney failure is a major health problem worldwide. Patients with end-stage renal disease require intensive medical support by dialysis or kidney transplantation. Current methods for diagnosis of kidney disease are either invasive or insensitive, and renal function may decline by as much as 50% before it can be detected using current techniques. The goal of this study was, therefore, to identify biomarkers of kidney disease (associated with renal fibrosis) that can be used for the development of a non-invasive clinical test for early disease detection. We utilized two protein-profiling technologies (SELDI-TOF MS and 2-D) to screen the plasma and kidney proteome for aberrantly expressed proteins in an experimental mouse model of unilateral uretric obstruction, which mimics the pathology of human renal disease. Several differentially regulated proteins were detected at the plasma level of day-3-obstructed animals, which included serum amyloid A1, fibrinogen α, haptoglobin precursor protein, haptoglobin and major urinary proteins 11 and 8. Differentially expressed proteins detected at the tissue level included ras-like activator protein 2, haptoglobin precursor protein, malate dehydrogenase, α enolase and murine urinary protein (all p<0.05 versus controls). Immunohistochemistry was used to confirm the up-regulation of fibrinogen. Interestingly, these proteins are largely separated into four major classes: (i) acute-phase reactants (ii) cell-signaling molecules (iii) molecules involved in cell growth and metabolism and (iv) urinary proteins. These results provide new insights into the pathology of obstructive nephropathy and may facilitate the development of specific assay(s) to detect and monitor renal fibrosis.  相似文献   
105.
This paper describes the development and evaluation of the Quick Exposure Check (QEC), which is an observational tool developed for Occupational Safety and Health (OSH) practitioners to assess exposure to risks for work-related musculoskeletal disorders and provide a basis for ergonomic interventions. The tool is based on epidemiological evidence and investigations of OSH practitioners' aptitudes for undertaking assessments. It has been tested, modified and validated using simulated and workplace tasks, in two phases of development, with participation of 206 practitioners. The QEC allows the four main body areas to be assessed and involves practitioners and workers in the assessment. Trials have determined its usability, intra- and inter-observer reliability, and validity which show it is applicable to a wide range of working activities. The tool focuses primarily on physical workplace factors, but also includes the evaluation of psychosocial factors. Tasks can normally be assessed within 10min. It has a scoring system, and exposure levels have been proposed to guide priorities for intervention. Subsequently it should be used to evaluate the effectiveness of any interventions made. The QEC can contribute to a holistic assessment of all the elements of a work system.  相似文献   
106.
A modular infrared spectrometer with microsampling and cryosampling capabilities has been designed, constructed, and tested. The main design features and preliminary results are discussed, and some strengths of the final instrument, when used in the optical characterization of superconducting materials, are presented.  相似文献   
107.
Two experiments were conducted to examine the effects of cooking parameters, including final internal temperature (65, 72·5 or 80°C), on the eating quality of pork. Assessments were made by a 10-member trained taste panel. In Experiment 1 on loin steaks (m. longissimus) from 28 carcasses weighing 66 ± 1·9 (SD) kg, increasing the final internal temperature from 65 to 80°C had the following effects on mean scores (1-8): tenderness -1·0; juiciness -1·5, pork flavour +0·6 and abnormal flavour -0·5. The medium temperature of 72·5°C was suggested as ideal. In Experiment 2 on leg roasts (m. gluteobiceps) from 96 carcasses weighing 65 + 2·7 (SD) kg, increasing the final internal temperature from 65 to 80°C had the following effects on mean scores (1-8): tenderness -0·2 (not significant), juiciness -0·6, pork flavour +0·3 and abnormal flavour -0·5. The effects of final internal temperature were therefore smaller in roasts and temperatures towards the upper end of the range would be recommended for ideal eating quality, balancing small losses in tenderness and juiciness against gains in flavour scores. Although the experiments were not designed to examine source and sex effects there was evidence that tenderness can be improved through the use of Duroc genes and pelvic suspension of carcasses and no evidence of differences in eating quality between entire males and females.  相似文献   
108.
Soft robots adapt passively to complex environments due to their inherent compliance, allowing them to interact safely with fragile or irregular objects and traverse uneven terrain. The vast tunability and ubiquity of textiles has enabled new soft robotic capabilities, especially in the field of wearable robots, but existing textile processing techniques (e.g., cut-and-sew, thermal bonding) are limited in terms of rapid, additive, accessible, and waste-free manufacturing. While 3D knitting has the potential to address these limitations, an incomplete understanding of the impact of structure and material on knit-scale mechanical properties and macro-scale device performance has precluded the widespread adoption of knitted robots. In this work, the roles of knit structure and yarn material properties on textile mechanics spanning three regimes–unfolding, geometric rearrangement, and yarn stretching–are elucidated and shown to be tailorable across unique knit architectures and yarn materials. Based on this understanding, 3D knit soft actuators for extension, contraction, and bending are constructed. Combining these actuation primitives enables the monolithic fabrication of entire soft grippers and robots in a single-step additive manufacturing procedure suitable for a variety of applications. This approach represents a first step in seamlessly “printing” conformal, low-cost, customizable textile-based soft robots on-demand.  相似文献   
109.
Methanol steam reforming (MSR) is viewed as an important technology in the growth of a future hydrogen economy, with methanol serving as an easily transportable and storable liquid hydrogen carrier. However, the thermocatalytic MSR reaction is energy intensive as it requires high temperatures. Herein, a novel L-Cu catalyst is successfully fabricated for photo-driven MSR through reduction of CuAl layered double hydroxide (CuAl-LDH) nanosheets. L-Cu offers outstanding activity for the photothermal conversion of methanol and water to hydrogen (160.5 µmol gcat−1 s−1) under ultraviolet-visible irradiation, with this rate being much higher than that achieved for L-Cu at the same temperature in the dark. Characterization studies using X-ray diffraction, X-ray photoelectron spectroscopy, X-ray absorption spectroscopy, and high-resolution transmission electron microscopy determine that L-Cu catalyst comprise Cu nanoparticles on an amorphous alumina support. Computational calculations reveale that Cu localized surface plasmon resonance effects promote the activation of H2O, thereby underpinning the remarkable hydrogen production rates achieved during photo-driven MSR. This study introduces a novel photothermal strategy for hydrogen generation from methanol, demonstrating the enormous potential of photothermal catalysis in the chemical and energy sectors.  相似文献   
110.
Real-Time Systems - This paper presents results and observations from a survey of 120 industry practitioners in the field of real-time embedded systems. The survey provides insights into the...  相似文献   
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