Experiments and simulations of short-pulse laser-pumped extreme ultraviolet lasers

Recent experimental work on the development of extreme ultraviolet lasers undertaken using as the pumping source the VULCAN laser at the Rutherford Appleton Laboratory is compared to detailed simulations. It is shown that short duration (/spl sim/picosecond) pumping can produce X-ray laser pulses of a few picosecond duration and that measurement of the emission from the plasma can give an estimate of the duration of the gain coefficient. The Ehybrid fluid and atomic physics code developed at the University of York is used to simulate X-ray laser gain and plasma emission. Two postprocessors to the Ehybrid code are utilized: 1) to raytrace the X-ray laser beam amplification and refraction and 2) to calculate the radiation emission in the kiloelectronvolt photon energy range. The raytracing and spectral simulations are compared, respectively, to measured X-ray laser output and the output of two diagnostics recording transverse X-ray emission. The pumping laser energy absorbed in the plasma is examined by comparing the simulations to experimental results. It is shown that at high pumping irradiance (>10/sup 15/ Wcm/sup -2/), fast electrons are produced by parametric processes in the preformed long scalelength plasmas. These fast electrons do not pump the population inversion and so pumping efficiency is reduced at high irradiance.     

Estimation of Length Limits for Integral Bridges Built on Clay

In this paper, the maximum length limits for integral bridges built on clay are determined as a function of the ability of steel H-piles supporting the abutments to sustain thermal-induced cyclic displacements and the flexural capacity of the abutment. First, H-pile sections that can accommodate large plastic deformations are determined considering their local buckling instability. Then, a low-cycle fatigue damage model is used to determine the maximum cyclic deformations that such piles can sustain. Next, nonlinear static pushover analyses of two typical integral bridges are conducted to study the effect of various geometric, structural, and geotechnical parameters on the performance of integral bridges subjected to uniform temperature variations. Using the pushover analyses results, design guidelines are developed to enhance and determine the maximum length limits for integral bridges built on clay. It is recommended that the maximum length of concrete integral bridges be limited to 210 m (689 ft) in cold climates and 260 m (853 ft) in moderate climates and that of steel integral bridges be limited to 120 m (394 ft) in cold climates and 180 m (590 ft) in moderate climates.     

Molecular mechanism of temporal physico/chemical changes that take place during imidization of polyamic acid: Coupled real-time rheo-optical and IR dichroism measurements

Multiple overlapping physical and chemical changes often take place during casting/drying and imidization from PMDA-ODA polyamic acid precursors from cast solutions. To shed light into details of these complex phenomena, we designed a unique real time measurement system that combines true stress, true strain, in-plane birefringence and temperature with polarized ultra-rapid scan FT-IR spectrometry (URS-FT-IR). At the early stages of heating (21°C–130 °C), initially isotropic solution cast film was observed to develop stress and birefringence as the solvent decomplexed and evaporated without showing any imidization as it was held in uniaxially constrained state. At a temperature around 130 °C, the onset of imidization reaction was detected while the stress went through a maximum. Beyond this stage, the evaporation of bound solvent and chemical conversion was observed to take place simultaneously and this is accompanied by a steady increase in birefringence. As the majority of the bound solvent evaporated, the stress and birefringence values started leveling off at long times.     

Bridging multi-scale approach to consider the effects of local deformations in the analysis of thin-walled members

Thin-walled members that have one dimension relatively large in comparison to the cross-sectional dimensions are usually modelled by using beam-type one-dimensional finite elements. Beam-type elements, however, are based on the assumption of rigid cross-section, thus they only allow considerations associated with the beam axis behaviour such as flexural-, torsional- or lateral-buckling and cannot consider the effects of local deformations such as flange local buckling or distortional buckling. In order to capture the local effects of this type shell-type finite element models can be used. Based on the Bridging multi-scale approach, this study proposes a numerical technique that is able to split the global analysis, which is performed by using simple beam-type elements, from the local analysis which is based on more sophisticated shell-type elements. As a result, the proposed multi-scale method allows the usage of shell elements in a local region to incorporate the local deformation effects on the overall behaviour of thin-walled members without necessitating a shell-type model for the whole member. Comparisons with full shell-type analysis are provided in order to illustrate the efficiency of the method developed herein.     

ASRSM: A Sequential Experimental Design for Response Surface Optimization

Most preset response surface methodology (RSM) designs offer ease of implementation and good performance over a wide range of process and design optimization applications. These designs often lack the ability to adapt the design on the basis of the characteristics of application and experimental space so as to reduce the number of experiments necessary. Hence, they are not cost‐effective for applications where the cost of experimentation is high or when the experimentation resources are limited. In this paper, we present an adaptive sequential response surface methodology (ASRSM) for industrial experiments with high experimentation cost, limited experimental resources, and high design optimization performance requirement. The proposed approach is a sequential adaptive experimentation approach that combines concepts from nonlinear optimization, design of experiments, and response surface optimization. The ASRSM uses the information gained from the previous experiments to design the subsequent experiment by simultaneously reducing the region of interest and identifying factor combinations for new experiments. Its major advantage is the experimentation efficiency such that for a given response target, it identifies the input factor combination (or containing region) in less number of experiments than the classical single‐shot RSM designs. Through extensive simulated experiments and real‐world case studies, we show that the proposed ASRSM method outperforms the popular central composite design method and compares favorably with optimal designs. Copyright © 2012 John Wiley & Sons, Ltd.     

Serum iron as an indicator of acute inflammation in cattle

The aim of this study was to assess the value of serum iron concentration in the diagnosis of acute inflammation in cattle. The diagnostic value of this approach was compared with that of various other hematological tests, including commonly used techniques that measure the levels of various other acute-phase proteins. The study population comprised 10 cows with acute traumatic reticuloperitonitis (RPT group) and 10 cows with acute mastitis (mastitis group) admitted to the Veterinary Teaching Hospital at Firat University (Elazi?, Turkey). Ten cows from local barns, kept and fed under same conditions as the diseased animals, were used as controls. After the clinical examination, blood samples were collected for biochemical, hematological, and acute-phase protein (haptoglobin, serum amyloid A, α-1 acid glycoprotein, and fibrinogen) analyses. The mean levels of serum iron in the RPT, mastitis, and control groups were 6.00, 7.82, and 26.78 µmol/L, respectively. Serum iron level was significantly reduced in the RPT and mastitis groups. The results of this study indicate that serum iron analysis, preferably in combination with other markers of inflammation, may be a useful diagnostic tool for acute inflammation in cattle. Because serum iron measurement is individually available and easily applicable, it may be used for clinical cases as well as the determination of herd health.