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排序方式: 共有1768条查询结果,搜索用时 218 毫秒
71.
J. Azevedo I. Fernandes P. Lopes I. Roseira M. Cabral N. Mateus V. Freitas 《European Food Research and Technology》2014,239(6):951-960
Considering the enological interest of cork, this study aimed to identify and quantify the phenolic compounds able to migrate from different classes (natural cork stoppers “Flor” and “Third” quality and microagglomerate cork stopper) of cork stoppers into bottled wine model solutions. Another aim was to evaluate some antioxidant and biological features of cork phenolics that migrated into the wine model solutions. The main phenolic acids and aldehydes detected were as follows: gallic and protocatechuic acid detected both around 3.5 mg/L and vanillin and protocatechuic aldehyde detected around 2.5 and 1.5 mg/L after 27 months of bottling, respectively. Trace amounts of more complex polyphenols, namely hydrolysable tannins (castalagin/vescalagin and mongolicain A/B), were also detected. Two antioxidant features of the wine model solutions bottled with different wine cork stoppers were studied, namely the antiradical capacity and the reducing capacity, being the natural cork stoppers the ones with the higher activities. The intestinal absorption of the compounds in each wine model solution after 27 months in bottled was evaluated. The simpler phenolic compounds were able to cross Caco-2 cell model. The antiproliferative activity of the same wine model solutions was also evaluated against gastric and breast cancer cells. All samples were active against the two cell lines, which highlight the possible health outcomes of wine sealed with cork stoppers. 相似文献
72.
73.
Nuno Lopes Paulo Vila Real Luís Simões da Silva Jean-Marc Franssen 《Fire Technology》2010,46(1):91-108
In this paper, the structural response of stainless steel thin-walled elements submitted to fire is analysed numerically by
means of the geometrically and materially non-linear Finite Element program SAFIR, including imperfections. In order to make
these simulations, two main changes in the program were made: (i) the code was changed in order to deal with the stainless
steel 2D material constitutive law to be used with shell elements and (ii) the possibility of the program to take into account
residual stresses with shell finite elements was introduced. The stainless steel stress–strain relationship at high temperatures
was based on the one presented in part 1.2 of Eurocode 3. To model the strain hardening exhibited by the stainless steels,
using the shell element formulation, an approximation to the Eurocode 3 constitutive law was needed. Local and global geometrical
imperfections were considered in the simulations. The paper shows the influence of the residual stresses on the ultimate load-carrying
capacity of thin-walled stainless steel structural elements in case of fire. 相似文献
74.
Flavio L. Souza Kirian P. Lopes Edson R. Leite 《Solar Energy Materials & Solar Cells》2009,93(3):362-368
Doped and undoped hematite films for photoelectrochemical hydrogen production were prepared by spin-coating deposition solution (SCDS). To understand the influence of the Si-doping and identify the critical parameters of the proposed SCDS method an extensive characterization was conducted. The Si-doped hematite exhibited higher photocurrent response when compared with undoped films. We have shown that the crystallographic orientation degree of the films appears to be a dominant factor affecting the photocurrent. The performance of our hematite electrodes is well below the maximum theoretical efficiency and the conceivable explanation could be given by the high value of recombination phenomena (electron/hole pair). 相似文献
75.
Magalhaes KD Costa LS Fidelis GP Oliveira RM Nobre LT Dantas-Santos N Camara RB Albuquerque IR Cordeiro SL Sabry DA Costa MS Alves LG Rocha HA 《International journal of molecular sciences》2011,12(5):3352-3365
In the present study, six families of sulfated polysaccharides were obtained from seaweed Dictyopteris delicatula by proteolytic digestion, followed by acetone fractionation and molecular sieving on Sephadex G-100. Chemical analyses demonstrated that all polysaccharides contain heterofucans composed mainly of fucose, xylose, glucose, galactose, uronic acid, and sulfate. The fucans F0.5v and F0.7v at 1.0 mg/mL showed high ferric chelating activity (~45%), whereas fucans F1.3v (0.5 mg/mL) showed considerable reducing power, about 53.2% of the activity of vitamin C. The fucan F1.5v presented the most prominent anticoagulant activity. The best antiproliferative activity was found with fucans F1.3v and F0.7v. However, F1.3v activity was much higher than F0.7v inhibiting almost 100% of HeLa cell proliferation. These fucans have been selected for further studies on structural characterization as well as in vivo experiments, which are already in progress. 相似文献
76.
Bike Denise H.; Norcross John C.; Schatz Danielle M. 《Canadian Metallurgical Quarterly》2009,46(1):19
In this replication and extension of a national survey of psychotherapists conducted in 1987, American psychologists (n = 219), counselors (n = 191), and social workers (n = 192) reported in 2007 on the processes and outcomes of their personal therapy experiences. Of the 85% who sought therapy at least once, women, men, and members of all three professions were equally as likely to have received personal treatment. Their top reasons for seeking therapy were marital–couple distress (20%), depression (13%), need for self-understanding (12%), and anxiety–stress (10%). Approximately 24% used psychotropic medication in combination with personal therapy. More than 90% of therapists reported positive outcomes across multiple domains. The modal lasting lessons from personal treatment related to therapist reliability, skill, and empathy. The results are tentatively compared with those obtained in 1987, thus chronicling the evolution of personal therapy among psychologists and social workers during the past 20 years. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
77.
Tony Minoru Tamura Lopes Andre Augusto Ciré Cid Carvalho de Souza Arnaldo Vieira Moura 《Constraints》2010,15(2):151-189
Brazilian petrobras is one of the world largest oil companies. Recurrently, it faces a very difficult planning and scheduling problem: how to
operate a large pipeline network in order to adequately transport oil derivatives and biofuels from refineries to local markets.
In spite of being more economical and environmentally safer, the use of a complex pipeline network poses serious operational
difficulties related to resource allocation and temporal constraints. The current approaches known from the literature only
consider a few types of constraints and restricted topologies, hence they are far from being applicable to real instances
from petrobras. We propose a hybrid framework based on a two-phase problem decomposition strategy. A novel Constraint Programming (CP) model
plays a key role in modelling operational constraints that are usually overlooked in literature, but that are essential in
order to guarantee viable solutions. The full strategy was implemented and produced very adequate results when tested over
large real instances. 相似文献
78.
Leonardo S. Lopes Filipe S. Q. Silva Adriana S. Silva Isabella F. Delgado 《Journal of surfactants and detergents》2013,16(3):445-448
Enzymatic detergents are widely used in health services. These products should be controlled to ensure their activity. In this paper, a UV spectrophotometric method for the determination of proteolytic activity in enzymatic detergents was validated. An artificial substrate (azocasein) was used to quantify the enzyme activity at 340 nm. The results showed that the method was satisfactory in respect to its specificity, linearity, precision, accuracy and robustness. This method fulfills both ICH’s and Brazilian criteria, demonstrating its suitability for routine analysis as well as its potential application for regulatory purposes. 相似文献
79.
Régis Lopes Correa Fernanda Prieto Bruckner Renan de Souza Cascardo Poliane Alfenas-Zerbini 《International journal of molecular sciences》2013,14(2):4030-4049
The F-box domain is a protein structural motif of about 50 amino acids that mediates protein–protein interactions. The F-box protein is one of the four components of the SCF (SKp1, Cullin, F-box protein) complex, which mediates ubiquitination of proteins targeted for degradation by the proteasome, playing an essential role in many cellular processes. Several discoveries have been made on the use of the ubiquitin–proteasome system by viruses of several families to complete their infection cycle. On the other hand, F-box proteins can be used in the defense response by the host. This review describes the role of F-box proteins and the use of the ubiquitin–proteasome system in virus–host interactions. 相似文献
80.
Allen Daniel N.; Randall Carol; Bello Danielle; Armstrong Christina; Frantom Linda; Cross Chad; Kinney Jefferson 《Canadian Metallurgical Quarterly》2010,24(2):244
Working memory deficits have been identified in bipolar disorder, but there is evidence suggesting that these deficits may be markers for psychosis rather than affective disorder. The current study examined this issue by comparing two groups of individuals with bipolar disorder, one with psychotic features and one without psychotic features, with a group of normal controls. Working memory was conceptualized as a multicomponent system that includes auditory and visuospatial short-term stores, executive control processes, and an episodic buffer that allows for communication between short- and long-term memory stores (Baddeley & Logie, 1999). Results indicated that only executive control processes significantly differentiated the psychotic and nonpsychotic bipolar groups, although visuospatial working memory differentiated both bipolar groups from controls. The results support the idea that some aspects of working memory performance are markers for psychosis, while others may be more general markers for bipolar disorders. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献