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排序方式: 共有151条查询结果,搜索用时 312 毫秒
61.
Trung ZH Kukurugya F Takacova Z Orac D Laubertova M Miskufova A Havlik T 《Journal of hazardous materials》2011,192(3):1100-1107
During the steel production in the basic oxygen furnace (BOF), approximately 7-15 kg of dust per tonne of produced steel is generated. This dust contains approximately 1.4-3.2% Zn and 54-70% Fe. Regarding the zinc content, the BOF dust is considered to be highly problematic, and therefore new technological processes for recycling dusts and sludge from metallurgical production are still searched for. In this study the hydrometallurgical processing of BOF sludge in the sulphuric acid solutions under atmospheric pressure and temperatures up to 100 °C is investigated on laboratory scale. The influence of sulphuric acid concentration, temperature, time and liquid to solid ratio (L:S) on the leaching process was studied. The main aim of this study was to determine optimal conditions when the maximum amount of zinc passes into the solution whilst iron remains in a solid residue. 相似文献
62.
G. Kocic R. Pavlovic G. Nikolic A. Veljkovic S. Panseri L.M. Chiesa T. Andjelkovic T. Jevtovic-Stoimenov D. Sokolovic T. Cvetkovic S. Stojanovic H. Kocic R. Nikolic 《Journal of dairy science》2014
Hyperuricemia is a biochemical hallmark of gout, renal urate lithiasis, and inherited purine disorders, and may be a result of enormous ATP breakdown or purine release as a result of cardiovascular disease, hypertension, kidney disease, eclampsia, obesity, metabolic syndrome, psoriasis, tumor lysis syndrome, or intense physical training. The beneficial role of dairy products on hyperuricemia management and prevention is well documented in the literature. The primary aim of our experimental study was to examine the effect of milk dietary regimen (commercial 1.5% fat UHT milk or patented depurinized milk) compared with allopurinol therapy on experimental hyperuricemia induced by oxonic acid in rats. Principal component analysis was applied on a data set consisting of 11 variables for 8 different experimental groups. Among the 11 parameters measured (plasma uric acid and the liver parameters NFκB-p65, Akt kinase/phospho-Akt kinase, ERK kinase/phospho-ERK kinase, IRAK kinase/phospho IRAK kinase, p38/phospho-p38, and DNase), Akt/phospho Akt and ERK/phospho-ERK signaling were extracted as the most discriminating. We also compared the content of various potentially toxic compounds (sulfur compounds, ketones, aldehydes, alcohols, esters, carboxylic acids, and phthalates) in untreated commercial milk and depurinized milk. Of all the compounds investigated in this study that were observed in commercial milk (24 volatile organic compounds and 4 phthalates), 6 volatile organic compounds were not detected in depurinized milk. For almost all of the other compounds, significant decreases in concentration were observed in depurinized milk compared with commercial milk. In conclusion, a depurinized milk diet may be recommended in nutritional treatment of primary and secondary hyperuricemia to avoid uric acid and other volatile, potentially toxic compounds that may slow down liver regeneration and may induce chronic liver diseases. 相似文献
63.
Gordana Kocic Dusan Sokolovic Tatjana Jevtovic Tatjana Cvetkovic Andrej Veljkovic Hristina Kocic Svetlana Stojanovic Aneta Jovanovic Jelena Jovanovic Petar Zivkovic 《Journal of dairy science》2014
Cardiovascular repair and myocardial contractility may be improved by migration of bone marrow stem cells (BMSC) and their delivery to the site of injury, a process known as BMSC homing. The aim of our study was to examine the dietary effect of a newly patented depurinized milk (DP) that is almost free of uric acid and purine and pyrimidine compounds compared with a standard commercial 1.5% fat UHT milk diet or allopurinol therapy in rat experimental hyperuricemia. Bone marrow stem cell potential (BMCD34+, CD34-postive bone marrow cells), plasma oxidative stress parameters [advanced oxidation protein products, AOPP) and thiobarbituric acid reactive substances (TBARS)], myocardial damage markers [creatine phosphokinase (CPK), aspartate aminotransferase (AST), and lactate dehydrogenase (LDH)], plasma cholesterol, and high-density lipoprotein cholesterol were investigated. The DP milk diet significantly increased the number of BMCD34+ stem cells compared with commercial UHT milk. Allopurinol given alone also increased the number of BMCD34+. Hyperuricemia caused a significant increase in all plasma enzyme markers for myocardial damage (CPK, LDH, and AST). A cardioprotective effect was achieved with allopurinol but almost equally with DP milk and more than with commercial milk. Regarding plasma AOPP, TBARS, and cholesterol levels, the most effective treatment was DP milk. In conclusion, the protective role of a milk diet on cardiovascular function may be enhanced through the new depurinized milk diet, which may improve cardiovascular system function via increased bone marrow stem cell regenerative potential, decreased plasma oxidative stress parameters, and decreased levels of myocardial damage markers and cholesterol. New dairy technology strategies focused on eliminating harmful milk compounds should be completely nontoxic. Novel milk products should be tested for their ability to improve tissue repair and function. 相似文献
64.
Presented is an approximate method for the vibration analysis of nuclear reactor subassembly ducts in form of slender thin-walled polygonal shells with hexagonal cross section. The method is based on the semimembrane shell theory. Inadequacies of this approximate theory are not expected to play a significant role in the determination of fundamental natural frequencies. According to the simplified theory employed, three basic types of motion appear as independent: purely longitudinal vibrations, flexural vibrations and distortional vibrations. 相似文献
65.
Experimental investigation of liquid water formation and transport in a transparent single-serpentine PEM fuel cell 总被引:1,自引:0,他引:1
Liquid water formation and transport were investigated by direct experimental visualization in an operational transparent single-serpentine PEM fuel cell. We examined the effectiveness of various gas diffusion layer (GDL) materials in removing water away from the cathode and through the flow field over a range of operating conditions. Complete polarization curves as well as time evolution studies after step changes in current draw were obtained with simultaneous liquid water visualization within the transparent cell. The level of cathode flow field flooding, under the same operating conditions and cell current, was recognized as a criterion for the water removal capacity of the GDL materials. When compared at the same current density (i.e. water production rate), higher amount of liquid water in the cathode channel indicated that water had been efficiently removed from the catalyst layer.
Visualization of the anode channel was used to investigate the influence of the microporous layer (MPL) on water transport. No liquid water was observed in the anode flow field unless cathode GDLs had an MPL. MPL on the cathode side creates a pressure barrier for water produced at the catalyst layer. Water is pushed across the membrane to the anode side, resulting in anode flow field flooding close to the H2 exit. 相似文献
66.
A simple one-step NaCl-assisted microwave-solvothermal method has been developed for the preparation of monodisperse α-Fe2O3 mesoporous microspheres. In this approach, Fe(NO3)3 · 9H2O is used as the iron source, and polyvinylpyrrolidone (PVP) acts as a surfactant in the presence of NaCl in mixed solvents
of H2O and ethanol. Under the present experimental conditions, monodisperse α-Fe2O3 mesoporous microspheres can form via oriented attachment of α-Fe2O3 nanocrystals. One of the advantages of this method is that the size of α-Fe2O3 mesoporous microspheres can be adjusted in the range from ca. 170 to ca. 260 nm by changing the experimental parameters.
High photocatalytic activities in the degradation of salicylic acid are observed for α-Fe2O3 mesoporous microspheres with different specific surface areas. 相似文献
67.
A study of reflective interference spectroscopy [RIfS] properties of nanoporous anodic aluminium oxide [AAO] with the aim
to develop a reliable substrate for label-free optical biosensing is presented. The influence of structural parameters of
AAO including pore diameters, inter-pore distance, pore length, and surface modification by deposition of Au, Ag, Cr, Pt,
Ni, and TiO2 on the RIfS signal (Fabry-Perot fringe) was explored. AAO with controlled pore dimensions was prepared by electrochemical
anodization of aluminium using 0.3 M oxalic acid at different voltages (30 to 70 V) and anodization times (10 to 60 min).
Results show the strong influence of pore structures and surface modifications on the interference signal and indicate the
importance of optimisation of AAO pore structures for RIfS sensing. The pore length/pore diameter aspect ratio of AAO was
identified as a suitable parameter to tune interferometric properties of AAO. Finally, the application of AAO with optimised
pore structures for sensing of a surface binding reaction of alkanethiols (mercaptoundecanoic acid) on gold surface is demonstrated. 相似文献
68.
Lee GS Miele LF Turhan A Lin M Hanidziar D Konerding MA Mentzer SJ 《Microscopy research and technique》2009,72(2):85-92
Quantitative assessment of microvascular structure is relevant to the investigations of ischemic injury, reparative angiogenesis and tumor revascularization. In light microscopy applications, thick tissue specimens are necessary to characterize microvascular networks; however, thick tissue leads to image distortions due to out-of-focus light. Structured illumination confocal microscopy is an optical sectioning technique that improves contrast and resolution by using a grid pattern to identify the plane-of-focus within the specimen. Because structured illumination can be applied to wide-field (nonscanning) microscopes, the microcirculation can be studied by sequential intravital and confocal microscopy. To assess the application of structured illumination confocal microscopy to microvessel imaging, we studied cell-sized microspheres and fused silica microcapillary tissue phantoms. As expected, structured illumination produced highly accurate images in the lateral (X-Y) plane, but demonstrated a loss of resolution in the Z-Y plane. Because the magnitude of Z-axis distortion was variable in complex tissues, the silica microcapillaries were used as spatial calibration standards. Morphometric parameters, such as shape factor, were used to empirically optimize Z-axis software compression. We conclude that the silica microcapillaries provide a useful tissue phantom for in vitro studies as well as spatial calibration standard for in vivo morphometry of the microcirculation. 相似文献
69.
Dr. Mijoon Lee Dr. Dusan Hesek Elena Lastochkin David A. Dik Dr. Bill Boggess Prof. Shahriar Mobashery 《Chembiochem : a European journal of chemical biology》2017,18(17):1696-1702
The major constituent of bacterial cell walls is peptidoglycan, which, in its crosslinked form, is a polymer of considerable complexity that encases the entire bacterium. A functional cell wall is indispensable for survival of the organism. There are several dozen enzymes that assemble and disassemble the peptidoglycan dynamically within each bacterial generation. Understanding of the nature of these transformations is critical knowledge for these events. Octasaccharide peptidoglycans were prepared and studied with seven recombinant cell‐wall‐active enzymes (SltB1, MltB, RlpA, mutanolysin, AmpDh2, AmpDh3, and PBP5). With the use of highly sensitive mass spectrometry methods, we described the breadth of reactions that these enzymes catalyzed with peptidoglycan and shed light on the nature of the cell wall alteration performed by these enzymes. The enzymes exhibit broadly distinct preferences for their substrate peptidoglycans in the reactions that they catalyze. 相似文献
70.