Bruce E. Wampold: Award for Distinguished Professional Contributions to Applied Research.

Presents the citation, biography, and selected bibliography for Bruce E. Wampold, the 2007 recipient of the American Psychological Association's Award for Distinguished Professional Contributions to Applied Research. Also presented is an article based on the author's award address delivered at the APA's 115th annual meeting, held August 17-20, 2007, in San Francisco, California. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Global complete observability and output-to-state stability imply the existence of a globally convergent observer

We consider systems which are globally completely observable and output-to-state stable. The former property guarantees the existence of coordinates such that the dynamics can be expressed in observability form. The latter property guarantees the existence of a state norm observer and therefore the possibility of bounding any continuous state functions. Both properties allow to conceptually build an observer from an approximation of an exponentially attractive invariant manifold in the space of the system state and an output driven dynamic extension. The proposed observer provides convergence to zero of the estimation error within the domain of definition of the solutions. The work of A. Astolfi is partly supported by the Leverhulme Trust.     

华北油田鄚东地区深井钻井液技术

鄚东地区钻井过程中经常发生垮塌、卡钻、井漏等复杂事故。该地区深井钻井采用了抑制性及封堵性较强的铵基沥青树脂高密度钻井液体系,并根据地层特点,对不同井段制定了相应的钻井液维护处理措施。结果表明,该钻井液体系抑制性好,抗温、抗污染能力强,性能稳定,成功地控制了复杂事故的发生,满足了该地区深层钻井的要求。     

The in vivo metabolic pattern of low-grade brain gliomas: a positron emission tomographic study using 18F-fluorodeoxyglucose and 11C-L-methylmethionine

OBJECTIVE: The object of the present study was to identify metabolic differences between low-grade astrocytomas and oligodendrogliomas and to improve their diagnosis and noninvasive assessment, because both types of tumors look very similar from the point of view of clinical and radiological data (as assessed by computed tomography and magnetic resonance imaging). METHODS: Before any aggressive treatment, 22 patients with primary low-grade gliomas (astrocytomas in 12 patients and oligodendrogliomas in 10) were investigated with positron emission tomography for both glucose metabolism (18F-fluorodeoxyglucose) and amino acid uptake (11C-L-methylmethionine). An original software that allows a full metabolic analysis of the tumor region of interest (defined from the T1-weighted magnetic resonance image) and compares tumor tissue uptake tracer concentrations with average healthy tissue values has been implemented for data processing. Heterogeneity of each individual tumor has been taken into account and was expressed in histograms, which provided data about the mean and also extreme and intermediate values of tracer concentrations and the way these values are distributed among the full tumor mass. RESULTS: It has been shown that both tumor types exhibit a glucose hypometabolism (slightly more pronounced with astrocytomas), whereas they strongly differ in methionine uptake, which is high in all oligodendrogliomas and either decreased, normal, or moderately increased in astrocytomas. This latter metabolic difference between both tumor populations may be partially explained by their different cell densities. CONCLUSION: This study suggests that despite similar radiological and clinical presentations, these two kinds of low-grade gliomas are metabolically different and could therefore have specific responses to different therapies. Moreover, their in vivo metabolic follow-up with positron emission tomography should rely on different parameters, depending on their histological type; methionine uptake may be more relevant than glucose metabolism in the follow-up of oligodendrogliomas.     

Cyclosporin A and cyclosporin SDZ PSC 833 enhance anti-CD5 ricin A-chain immunotoxins in human leukemic T cells

Recent studies have shown that cyclosporin A (CsA) may affect ricin A-chain immunotoxin (RTA-IT) therapy. In this study, we evaluated the ability of CsA and its nonimmunosuppressive analog, SDZ PSC 833, to enhance anti-CD5 T101 RTA-ITs in vitro. Both 4 mumol/L CsA and 4 mumol/L SDZ PSC 833 significantly and specifically enhanced the cytotoxic activity of T101 RTA-IT on the human lymphoblastic T-cell line, CEM III (101-fold and 105-fold, respectively). Furthermore, these Cs also enhanced the cytotoxicity of the more potent T101 F(ab')2 RTA-IT (ninefold and eightfold, respectively). The effect of human plasma, originating from four patients enrolled in a phase I high-dose CsA regimen, was examined on T101 RTA-IT cytotoxicity on CEM III cells. In each case, with plasma CsA levels between 3,090 and 4,860 ng/mL (2.5 to 4 mumol/L), a significant increase in T101 RTA-IT-mediated cytotoxicity was observed ranging from 31% to 60%. Neither CsA nor SDZ PSC 833 affected the rate of RTA-IT binding, internalization, intracellular trafficking, or degradation. Analysis of internalized T101 RTA-IT molecules showed that these were essentially intact, which suggests that these enhancers may act only on a small population of RTA-ITs that escapes present investigational techniques. In conclusion, because the concentrations used are clinically achievable, Cs appear to be promising agents for in vivo enhancement of RTA-ITs.     

f—x域内提高地震资料的信噪比

在 f-x 域,地震记录可以表示成有限个调频调幅正弦波的叠合,叠合的结果是一个连续且光滑的函数。我们可以用一个简单的 n 次多项式去逼近这个函数。本文提出了一种在 f-x 域用最小平方拟合原理消除随机噪声的新方法,并证明了在噪声为自噪以及空间采样足够密的条件下,拟合结果与噪声无关,即 f-x 域最小平方拟合处理可以有效地消除记录上的随机白噪,而对有效信号的破坏甚微。由于理论上允许振幅值及同相轴形态在空间上发生变化,因而该方法不具有混波作用,是高分辨率处理的理想工具。     

Minutes of the CPA Annual General Meeting.

The Annual General Meeting of the Canadian Psychological Association was held at the World Trade and Convention Centre, Halifax, Nova Scotia, on June 7,1985 at 4:00 p.m. The President, Elinor Ames, acted as Chair of the Meeting and the Administrative Officer, Brenda Stoneham, as Secretary. The minutes presented here include: Adoption of Agenda; Approval of Minutes; Report of the President; CPA Awards; Appointments; Finance; By-Laws, Rules, and Procedures; Membership and Journal Circulation; Executive Director's Report; Journal Reports; Division Reports; Annual Meetings; Committee Reports; Affiliations; Other Business; and Adjournment. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Phyllis A. Katz: Award for Distinguished Senior Career Contributions to the Public Interest.

Announces that Phyllis A. Katz has won the Award for Distinguished Senior Career Contributions to the Public Interest. The award is presented for the honoree's research on the origins and development of both racial and gender attitudes and her contributions to psychology in the public interest within the American Psychological Association. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Gold Medal Award for Life Achievement in the Application of Psychology: Edwin A. Fleishman.

The 2004 Gold Medal Award for Life Achievement in the Application of Psychology was awarded to Edwin A. Fleishman, for his significant contributions to the science and applications of psychology, which he has sustained over his remarkable career. He is cited for his research, which has had a profound influence on our understanding of human capabilities, their measurement, their development, and their application in the world of work. Through his many influential leadership roles, as president of the International Association of Applied Psychology and three divisions of the American Psychological Association, and as editor of the Journal of Applied Psychology, he has helped shape our profession. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Editors of APA Journals: 2004 Address List.

Presents the 2004 address list of editors of APA journals. (PsycINFO Database Record (c) 2010 APA, all rights reserved)