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101.
Bezerianos A Dragicevic P Fekete JD Bae J Watson B 《IEEE transactions on visualization and computer graphics》2010,16(6):1073-1081
GeneaQuilts is a new visualization technique for representing large genealogies of up to several thousand individuals. The visualization takes the form of a diagonally-filled matrix, where rows are individuals and columns are nuclear families. After identifying the major tasks performed in genealogical research and the limits of current software, we present an interactive genealogy exploration system based on GeneaQuilts. The system includes an overview, a timeline, search and filtering components, and a new interaction technique called Bring & Slide that allows fluid navigation in very large genealogies. We report on preliminary feedback from domain experts and show how our system supports a number of their tasks. 相似文献
102.
This paper concerns the properties of a few natural polysaccharides investigated in our laboratory. We also present the different techniques used in our group for a long time and their advantages to characterize polysaccharides. In a first part, the behavior of galactomannans with different chemical structures is discussed; the distribution of galactose units along the mannan backbone is very important. Then, xanthan is developed as one of the best thickening polymers due to its high intrinsic stiffness related to the helical conformation stabilized in the presence of excess salt. Gellan under native or deacylated structure is described to demonstrate the role of substituents on the physical properties in solution and especially on the sol–gel transition. The last part concerns the cooperative interaction between xanthan and galactomannan giving in specific conditions two different gels with a gel–sol melting transition around 25°C and 50–60°C, respectively, depending on the galactomannan microstructure. 相似文献
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104.
The present series of experiments were designed to examine a potential role for central descending pain facilitatory systems in mediating secondary hyperalgesia produced by topical application of mustard oil and measuring the nociceptive tail-flick reflex in awake rats. Topical application of mustard oil (100%) to the lateral surface of the hind leg produced a facilitation of the tail-flick reflex that was significantly reduced in spinal transected animals. Mustard oil hyperalgesia was also inhibited in animals that had received electrolytic lesions in the rostral ventromedial medulla (RVM). Intrathecal (i.t.) administration of the non-selective cholecystokinin (CCK) receptor antagonist proglumide (10 micrograms) prior to mustard oil application completely blocked both the lesser and greater hyperalgesic responses observed in spinal transected and normal animals, respectively, and produced an inhibition of the tail-flick reflex in normal animals. Administration of the selective CCKB receptor antagonist L-365260 i.t. dose-dependently inhibited mustard oil hyperalgesia (ID50 = 364 ng) at doses approximately 5-fold less than the CCKA receptor antagonist devazepide (ID50 = 1760 ng). Similar to spinal proglumide, microinjection of the neurotensin antagonist SR48692 (3.5 micrograms) into the RVM blocked mustard oil hyperalgesia and inhibited the tail-flick reflex. These data suggest that secondary hyperalgesia produced by mustard oil is mediated largely by a central, centrifugal descending pain facilitatory system which involves neurotensin in the RVM and spinal CCK (via CCKB receptors). The inhibition of the tail-flick reflex produced by mustard oil following spinal or supraspinal administration of receptor antagonists suggests concurrent activation of central descending facilitatory and inhibitory systems. 相似文献
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This article analyzes the factors that explain why groundwater can be over-exploited despite the existence of sophisticated water laws, institutions and effective state agencies responsible for water management. The analysis is based on a case study conducted in the Copiapó Valley in northern Chile. Based on an analysis of water use data, policy documents and interviews with a variety of stakeholders, the article highlights the state’s failure to perform some of its key missions and the ineffectiveness of groundwater users’ associations in water management despite a very supportive legal framework. The article concludes with some recommendations on how ensure long-term sustainable groundwater use. 相似文献
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108.
Radu Ispasoiu Tom Crawford Brian Johnston Chris Shaw Steven Kasapi Jason Goertz Olivier Rinaudo Peter Ouimet 《Microelectronics Reliability》2006,46(9-11):1504-1507
We have achieved a greater than 2.5× improvement in the acquisition time figure of merit of an EmiScope™ Time Resolved photon Emission (TRE)-based probe system, by optimization of the detector dark-count rate, photon detection efficiency, and timing jitter. The effects of detector after-pulsing were reduced by use of an optimized hold-off time. 相似文献