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排序方式: 共有523条查询结果,搜索用时 15 毫秒
21.
Dr. Jakob Franke Dr. Jeongwoon Kim John P. Hamilton Dr. Dongyan Zhao Gina M. Pham Krystle Wiegert-Rininger Emily Crisovan Linsey Newton Brieanne Vaillancourt Dr. Evangelos Tatsis Prof. Dr. C. Robin Buell Prof. Dr. Sarah E. O'Connor 《Chembiochem : a European journal of chemical biology》2019,20(1):83-87
Genome mining is a routine technique in microbes for discovering biosynthetic pathways. In plants, however, genomic information is not commonly used to identify novel biosynthesis genes. Here, we present the genome of the medicinal plant and oxindole monoterpene indole alkaloid (MIA) producer Gelsemium sempervirens (Gelsemiaceae). A gene cluster from Catharanthus roseus, which is utilized at least six enzymatic steps downstream from the last common intermediate shared between the two plant alkaloid types, is found in G. sempervirens, although the corresponding enzymes act on entirely different substrates. This study provides insights into the common genomic context of MIA pathways and is an important milestone in the further elucidation of the Gelsemium oxindole alkaloid pathway. 相似文献
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Polymorphism of M3AlX Phases (M = Ti,Zr, Hf; X = C,N) and Thermomechanical Properties of Ti3AlN Polymorphs 下载免费PDF全文
Yanhui Zhang Peter Franke Hans Jürgen Seifert Jingyang Wang 《Journal of the American Ceramic Society》2015,98(8):2570-2578
M3AlX (M = Ti/Zr/Hf, X = C/N) compounds are promising high‐temperature structural ceramics. However, their interesting polymorphism, thermomechanical stabilities, and thermal and mechanical properties were not fully understood. In this work, the polymorphisms of M3AX phases are investigated by combining first‐principles and lattice dynamics calculations. Only Ti3AlN shows polymorphic transition between the cubic and orthorhombic phases at around 1105 K; but other M3AlX phases do not display similar polymorphic phase transition. Furthermore, the temperature‐dependent heat capacity, thermal expansion, and elastic stiffness of Ti3AlN polymorphic phases are reported for the first time to explore the relationship between crystal structures, and mechanical and thermal properties. Ti3AlN polymorphs show anisotropic thermal expansion and elastic stiffness; and the orthorhombic Ti3AlN is suggested as a promising damage tolerant nitride, which has similar properties with the previously reported Zr3AlN and Hf3AlN. 相似文献
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H. Scaar G. Franke F. Weigler M. Delele E. Tsotsas J. Mellmann 《Drying Technology》2016,34(5):595-607
The aim of this study was to investigate the airflow distribution in a mixed-flow dryer (MFD) and to study the effect of different bed materials and air duct arrangements. The results were used to validate the numerical model developed in a previous work based on Computational Fluid Dynamics (CFD). A series of experiments have been conducted at a semi-technical MFD test dryer with horizontal and diagonal air duct arrangement. Wheat and rapeseed were used as bed materials. The experiments were performed under isothermal conditions. Two experimental methods were selected and adapted to the measuring problem—the measurement of the isobar distribution within the grain bed and the residence time analysis using the tracer gas pulse method. As could be shown, the isobar distributions measured for wheat and rapeseed agreed well with the model predictions. The numerical model could calculate the influence of the bed material with its different particle characteristics (e.g., particle shape, particle size, bed porosity). The results obtained from the residence time analysis confirmed the known quartering of the air stream flowing from one inlet air duct to the four surrounding outlet air ducts for the horizontal air duct arrangement; in the diagonal air duct arrangement, the air stream from one inlet air duct was nearly halved flowing to the two adjacent diagonal outlet air ducts. These results were confirmed by investigations of the air velocity distribution within the grain bulk. Further experiments are necessary to refine the model. The residence time and isobar measurements will be extended to study the influence of different air properties under real drying conditions, the effect of structural elements, and dryer designs. 相似文献
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A sensitive layer system of amorphous Teflon AF on silver has been coated on a glass substrate. With a monochromatic light source the reflectivity of the layer system as a function of the angle of incidence exhibits the surface-plasmon resonance as well as a set of leaky-mode resonances. These optical resonance phenomena are sensitive to small refractive-index changes that may be induced by diffusion of particles into the Teflon AF layer. On the basis of this effect, the aromatic vapors benzene; toluene; and o-, p-, and m-xylene have been investigated with different vapor concentrations. By selection of a distinct angle at a particular resonance, dynamic measurements can be performed. Assuming a diffusion process in accordance with Fick's law, the diffusion profile can be calculated as a function of time. As described by the Lorentz-Lorenz relation a refractive-index profile is induced that consequently interacts with the electromagnetic fields of the optical modes. With the function of the diffusion-induced refractive-index profile the shift of the resonance lines can be calculated from the measured reflectivity change as a function of time. The characteristic diffusion coefficients of the particular vapor allow for a distinction between the different types of aromate, even between the different xylenes. 相似文献
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Schwalbe HJ Bamfaste G Franke RP 《Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine》1999,213(1):41-48
Quality control in orthopaedic diagnostics according to DIN EN ISO 9000ff requires methods of non-destructive process control, which do not harm the patient by radiation or by invasive examinations. To obtain an improvement in health economy, quality-controlled and non-destructive measurements have to be introduced into the diagnostics and therapy of human joints and bones. A non-invasive evaluation of the state of wear of human joints and of the cracking tendency of bones is, as of today's point of knowledge, not established. The analysis of acoustic emission signals allows the prediction of bone rupture far below the fracture load. The evaluation of dry and wet bone samples revealed that it is possible to conclude from crack initiation to the bone strength and thus to predict the probability of bone rupture. 相似文献
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As assembly process planning fulfils the main function of connecting product design to production simulation and thus, the production system itself, a feasible software solution is needed to support this process. Thus, a novel concept is presented that aims at improving the integration of digital product design and assembly planning by introducing a consistent data structuring. This approach helps to reduce redundant tasks and supports the continuous data exchange. It is based on the use of assembly features, i.e. pre-defined geometry elements that contain additional technological information.The prototypical implementation of the concept focuses on the use of commercially available software tools, expanding them with additional functionality for the application of assembly features. The feature-based concept has been tested with a scenario from the automotive supplier industry. For the considered assembly, a comparison between the conventional and the feature-based planning approach is presented in the paper. It points out that the major advantages of the developed concept can be seen in an improved data consistency as well as a higher level of efficiency within the planning activities. 相似文献
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Löfstedt C Zhu J Kozlov MV Buda V Jirle EV Hellqvist S Löfqvist J Plass E Franke S Francke W 《Journal of chemical ecology》2004,30(3):643-658
Under an artificial light:dark cycle, females of Lampronia capitella were observed calling, with extended terminal abdominal segments, during the first 2 hr of the photoperiod. Extracts of terminal abdominal segments from females elicited large electroantennographic responses from male antennae. Gas chromatography with electroantennographic detection revealed three active peaks. Based on comparison of retention times and mass spectra of synthetic standards, these compounds were identified as (Z,Z)-9,11-tetradecadienol and the corresponding acetate and aldehyde. The electroantennographic activity of the four geometric isomers of all three compounds was investigated, and the respective (Z,Z)-isomer was found to be the most active in all cases. Aldehydes generally elicited larger antennal responses than alcohols, whereas acetates were the least active compounds. A subtractive trapping assay in the field, based on a 13:26:100 micrograms mixture of (Z,Z)-9,11-tetradecadienal, (Z,Z)-9,11-tetradecadienyl acetate, and (Z,Z)-9,11-tetradecadienol confirmed that all three compounds are pheromone components. Subtraction of (Z,Z)-9,11-tetradecadienol from the blend completely eliminated its attractiveness, whereas the other two-component blends showed reduced activity. This is the first pheromone identification from the monotrysian superfamily Incurvarioidea, confirming that the common pheromones among ditrysian moths (long-chain fatty acid derivatives comprising alcohols, acetates, and aldehydes with one or more double bonds) is not an autapomorphy of Ditrysia, but a synapomorphy of the more advanced heteroneuran lineages. 相似文献