某制革企业制革废水处理工程项目设计方案

河北省辛集市某制革企业制革废水处理工程设计规模为600 m~3/d。设计采用以"预处理+多功能池+AO"为主体的工艺,其中多功能池可根据使用需求灵活切换。由2015年1月~6月的运行数据可知,该工艺处理效果较好,运行稳定,实际运行出水水质优于设计值,且可实现污泥减量。并通过对各单元设计的详细介绍及运行数据分析,总结了设计、运行方面的经验。     

基于CAE的汽车档位手球结构优化及模具设计

利用Moldflow对某汽车档位手球塑料件结构进行分析,以此为参考,对塑料件结构作一定的改进,并对改进后的塑料件进行模具设计,介绍了模具结构分析及相关设计要点,并通过实际试模得到了合格塑料件。     

ROS-Mediated Anti-Tumor Effect of Coptidis Rhizoma against Human Hepatocellular Carcinoma Hep3B Cells and Xenografts

Coptidis Rhizoma is the dried rhizome from the Coptis chinensis Franch. that has been shown to have a number of beneficial pharmacological properties including antioxidant, anti-inflammatory, and anti-cancer effects. However, the anti-cancer effects of Coptidis Rhizoma on hepatocellular carcinoma (HCC) remain unclear. In this study, we investigated the anti-cancer properties of Coptidis Rhizoma ethanol extract (CR) in HCC Hep3B cells and in a xenograft mouse model. Our results showed that the CR significantly inhibited cell growth and induced apoptosis in Hep3B cells through increased expression of Bcl-2 associated x-protein (Bax) and cleavage of poly-ADP ribose polymerase (PARP), reduced expression of Bcl-2, and activated caspases. CR also increased the generation of intracellular reactive oxygen species (ROS), which caused a loss of mitochondrial membrane potential (MMP, ΔΨm) and activation of the mitochondria-mediated intrinsic apoptosis pathway. Moreover, N-acetylcysteine (NAC), a ROS inhibitor, markedly blocked the effects of CR on apoptotic pathways. CR also induced the expression of light chain 3 (LC3)-I/II, a key autophagy regulator, whereas CR-mediated autophagy was significantly suppressed by NAC. In addition, pre-treatment with NAC perfectly attenuated the inhibition of cell invasion and migration of CR-stimulated Hep3B cells. Furthermore, oral administration of CR suppressed Hep3B tumor growth in xenograft mice without toxicity, alterations to body weight, or changes in hematological and biochemical profiles. Taken together, our findings suggest that CR has anti-tumor effects that result from ROS generation, and may be a potential pharmacological intervention for HCC.     

Statistical analysis of manual segmentations of structures in medical images

The problem of extracting anatomical structures from medical images is both very important and difficult. In this paper we are motivated by a new paradigm in medical image segmentation, termed Citizen Science, which involves a volunteer effort from multiple, possibly non-expert, human participants. These contributors observe 2D images and generate their estimates of anatomical boundaries in the form of planar closed curves. The challenge, of course, is to combine these different estimates in a coherent fashion and to develop an overall estimate of the underlying structure. Treating these curves as random samples, we use statistical shape theory to generate joint inferences and analyze this data generated by the citizen scientists. The specific goals in this analysis are: (1) to find a robust estimate of the representative curve that provides an overall segmentation, (2) to quantify the level of agreement between segmentations, both globally (full contours) and locally (parts of contours), and (3) to automatically detect outliers and help reduce their influence in the estimation. We demonstrate these ideas using a number of artificial examples and real applications in medical imaging, and summarize their potential use in future scenarios.     

Lotka phenomenon in the words’ syntactic distribution complexity

To better understand the distribution of words in all kinds of syntactic structures, the paper calculates the word distribution in syntactic structures of both English and Chinese. On the basis of the calculation, the article presents the definition of the words’ syntactic distribution complexity. After arranging the Chinese and English words according to their own syntactic distribution complexity, respectively, the Lotka phenomenon can be clearly attested by the results. The discovery made in the paper reveals the law of the words’ syntactic distribution in linguistic studies on one hand and the statistically proven fact that Chinese words’ syntax is much more complex than that of the English after comparing the Lotka phenomenon of both Chinese and English words’ syntactic distribution complexity on the other hand.     

Quality models for venue recommendation in location-based social network

With the rapid development of location-based social networks (LBSNs), increasing media data is ceaselessly uploaded by users. The multimedia data is often scattered and not informative and consequently they can not directly represent the semantics of each venue. Most of prior works leverage the user’ travelling histories to recommend new venues to users. However, these works often focus on the users’ travelling histories, while ignore the concepts or the popular levels of venues. In this paper, we proposed a quality model for venue recommendation by utilizing multimedia data to predict the interested level of each venue. First, we apply the graph cut method to generate the latent textual topics. Second, we leverage visual data from Flickr to train concept detectors to automatically label visual information. Third, the weighted bipartite matching algorithm is implemented to generate the venue multimedia topics by bridging the textual information and the visual information. Finally, we utilize the matching cost to predict the popular level of venue for recommendation. The experiments have been conducted on the cross-platform datasets. The results demonstrate the superiority of the proposed model.     

无线网络在zigbee的技术及应用

当今社会最为突出的发展领域是无线网络技术的应用以及快速发展。本文就无线电技术即zigbee技术及其自身的特性进行了详细的分析,主要将优点与自身的构成方式进行了探讨。     

Safety-enhanced Collaborative Framework for Tele-operated Minimally Invasive Surgery Using a 7-DoF Torque-controlled Robot

International Journal of Control, Automation and Systems - In this paper, a safety-enhanced collaborative control framework is proposed for tele-operated minimally invasive surgery (MIS) using a...     

Ti掺杂对NaAlH4储氢性能的影响

采用基于密度泛函理论(DFT)的平面波赝势(PW-PP)方法,分别计算纯净以及掺杂Ti的NaAlH4和Na3AlH6的晶格结构参数、能量变化和电子态密度(DOS),分析比较Ti掺杂对NaAlH4和Na3AlH6储氢性能的影响。结果表明:Ti掺杂后的晶格结构比原纯净的NaAlH4和Na3AlH6稳定,且脱氢所需能量减少。Ti替代Na后,Ti吸引周围的H原子,使Al-H键变弱;Ti替代Al,Ti-H键比原Al-H键明显减弱,使掺杂后脱氢所需能量降低。通过对比分析Ti掺杂对NaAlH4和Na3AlH6结构和态密度的影响,得出Ti的催化作用主要发生在脱氢反应的第一步。