五步创造有效的规划

<正> 对一个团队和组织来说,创造一个有效的规划是最具挑战性的任务之一。规划在这里不是指几个简单的句子,而是一种对未来状态的彻底的清晰认识,它包括对价值观、步骤、结构、技术、工作角色和环境的明确认识。但问题是:需要采取什么样的步骤才能为自己的组织创造一个有效和可行的规划呢?本文介绍的模块提供了一些基本的步骤,它们能大大提高创造一个有效的规划的可能性。     

CompactPCI系统管理

~~CompactPCI系统管理@Jeff Munch$凌华科技!技术长暨国际PICMG 3.0委员会主席     

Effect of thermal treatment on ZnO substrate for epitaxial growth

ZnO is a highly efficient photon emitter, and has optical and piezoelectric properties that are attractive for a variety of applications in sensors and potentially optoelectronic devices such as emitters. Due to its identical stacking order and close lattice match to GaN, it is also being developed as a substrate material for GaN epitaxy. However, the surface finish of the ZnO is such that much of the damage induced by sawing and follow up mechanical polishing remains. We developed a thermal treatment method to eliminate surface damage on the 0 face of ZnO (0 0 0 1) to prepare it for epitaxial growth. Atomic force microscopy images of ZnO (0 0 0 1) annealed at 1050 °C for 3 h etc. show that residual scratches from mechanical polishing are removed and atomically flat, terrace-like surfaces are attained. In addition, low-temperature photoluminescence and high-resolution X-ray diffraction measurements have been employed to investigate the effect of annealing on ZnO substrates.     

选择正确的DC/DC转换器拓扑

基于电子设备的处理器系统设计人员经常在选择最佳电源架构时遇到困难。有时最佳的解决方案是插入式电源,而有时采用分立的元件组成的电源才是最佳解决方案。选择插入式电源解决方案相对来说比较直接,但对于缺乏电源设计经验的数字设计人员来说,设计一个分立电源解决方案可能会使他望而却步。大多 DC/DC 电源控制 IC 供应商均可提供有助于电路设计的详细辅助材料。但是,在开始电源设计之前,设计人员必须选择正确的拓扑。本文将介绍以下方法,来帮助为某些用于MCU、DSP及基于FPGA 的电子产品的最常用结构选择正确的电源拓扑。线性调节…     

Effect of quinidine on the interconversion kinetics between haloperidol and reduced haloperidol in humans: implications for the involvement of cytochrome P450IID6

Unequal metabolic responses to trauma by women and men have been suggested, but an explicit investigation demonstrating this conjecture has not been made. The responses of resting energy expenditure (REE) and nitrogen balance for 3 days before and 7 days after skeletal trauma were determined for female and male rats. Food intake and body weight were recorded daily, and 24-h urine samples were collected. Baseline REE and nitrogen balance were obtained for 3 consecutive days before induction of trauma. Then rats were divided into female trauma (n = 8), male trauma (n = 7), female control (n = 8), and male control (n = 7) groups. Trauma was produced by bilateral femoral fracture to anesthetized rats. Control rats were anesthetized without skeletal trauma. Traumatized rats were fed ad libitum for 7 days, and control rats were pair fed with the traumatized rats. The results showed that REE increased and nitrogen balance decreased in traumatized male rats relative to their controls. Traumatized female rats had increased REE and unchanged nitrogen balance compared with their controls. Traumatized female rats had a larger percentage increase in REE on days 5 through 7 than did traumatized male rats. These findings demonstrate a difference between female and male rats in response to trauma. Female rats use more energy and lose less nitrogen after trauma than do male rats. The results suggest that recommendations for increased energy and protein needs after trauma should consider the sex of the subject intended to be fed.     

Ex vivo expansion with stem cell factor and interleukin-11 augments both short-term recovery posttransplant and the ability to serially transplant marrow

The characterization of many cytokines involved in the control of hematopoiesis has led to intense investigation into their potential use in ex vivo culture to expand progenitor numbers. We have established the optimum ex vivo culture conditions that allow substantial amplification of transient engrafting murine stem cells and which, simultaneously, augment the ability to sustain serial bone marrow transplantation (BMT). Short-term incubation of unfractionated BM cells in liquid culture with stem cell factor (SCF) and interleukin-11 (IL-11) produced a 50-fold amplification of clonogenic multipotential progenitors (CFU-A). Following such ex vivo expansion, substantially fewer cells were required to rescue lethally irradiated mice. When transplanted in cell doses above threshold for engraftment, BM cells expanded ex vivo resulted in significantly more rapid hematopoietic recovery. In a serial transplantation model, unmanipulated BM was only able to consistently sustain secondary BMT recipients, but BM expanded ex vivo has sustained quaternary BMT recipients that remain alive and well more than 140 days after 4th degree BMT. These results show augmentation of both short-term recovery posttransplant and the ability to serially transplant marrow by preincubation in culture with SCF and IL-11.     

Gene Transfer Systems and Molecular Cloning in Group N Streptococci: A Review

Plasmid deoxyribonucleic acid of group N streptococci codes for a wide variety of important metabolic properties associated with dairy fermentations. The increasing knowledge of the genetics of these bacteria has created exciting possibilities for genetically constructing improved starter strains. A review of current literature is presented on the genetics of group N streptococci, especially the development and implications of gene transfer and molecular cloning systems for further genetic studies and for strain improvement. Functional properties of plasmid deoxyribonucleic acid and gene transfer systems, which include transduction, conjugation, transformation, and protoplast fusion, are reviewed and followed by a discussion of recent advances in gene cloning.