A Comparision of the Number of Rational Places of Certain Function Fields to the Hasse-Weil Bounds

We give explicitly the number of rational places of certain function fields in terms of the reciprocals of the zeros of the function fields in question. The results are then compared with the Hasse-Weil bounds by using the approximation theorems of Dirichlet and Kronecker and it turns out that in many of these function fields the number of rational places is near the upper Hasse-Weil bound. Keywords:Function fields, Diophantine approximation, Exponential sums.     

2,5-Dihydroxybenzoic acid butylamine and other ionic liquid matrixes for enhanced MALDI-MS analysis of biomolecules

The performance of the new ionic liquid MALDI-MS matrix 2,5-dihydroxybenzoic acid butylamine (DHBB) was assessed and compared to results obtained with the ionic liquid MALDI-MS matrixes alpha-cyano-4-hydroxycinnamic acid butylamine (CHCAB), 3,5-dimethoxycinnamic acid triethylamine (SinTri), and the frequently used solid MALDI matrixes 2,5-dihydroxybenzoic acid (DHB) and alpha-cyano-4-hydroxycinnamic acid (CHCA). The vacuum-stable, liquid consistency of ionic liquid matrix sample preparations considerably enhanced MALDI-MS analysis in terms of shot-to-shot reproducibility. Consequently, relative standard deviations serving as a measure for reproducibility of intensity-values acquired from 90 different spots on one MALDI-MS preparation were approximately one-half as high when solid DHB was replaced by the ionic liquid DHBB and eight times lower after exchange of solid CHCA by ionic liquid CHCAB. Interestingly, the ionic liquid MALDI matrix DHBB conserved the broad applicability of its solid analogue DHB, reduced MALDI induced fragmentation of monosialylated glycans and gangliosides, and was the superior ionic liquid matrix for MALDI-MS analysis of oligosaccharides and polymers, such as poly(ethylene glycol). It also worked well with glycoconjugates, peptides, and proteins; however, the tendency of DHBB to form multiple alkali adduct ions with peptides and proteins made CHCAB the ionic liquid matrix of choice for peptides. SinTri was the best ionic liquid matrix for proteins of high molecular weight, such as IgG. Furthermore, it was demonstrated for the first time that solvent properties and MALDI matrix properties of ionic liquids, such as DHBB, can be combined to enable fast, direct screening of an enzymatic reaction. This was proven by the desialylation of sialylactose with sialidase from Clostridium perfringens in the presence of diluted aqueous DHBB and subsequent direct MALDI-MS analysis of the reaction mixture.     

Coupling of light from an LED into a thin light guide by diffractive gratings

Ring-shaped and radial diffractive gratings are designed with rigorous diffraction theory to couple light of a nearly monochromatic LED into a thin planar light guide on the bottom side. The theoretical coupling efficiencies for ring-shaped and radial gratings are 41% and 66%, respectively. Optimized diffractive elements are manufactured with direct electron-beam lithography and reactive-ion-etching into SiO2 substrates. Good agreement between experimental and theoretical results for selected radial gratings is reached. Furthermore, the mass production tests using injection molding are carried out with good replicability.     

Studies of biosynthesis of waxes by developing jojoba seed: III. Biosynthesis of wax esters from Acyl-CoA and long chain alcohols

Acyl-CoA: alcohol transacylase activity was demonstrated in cell-free homogenates of developing jojoba seeds. The optimal pH was 8.0–8.1. Under optimal conditions, wax formation had a nearly linear relationship with extract concentration; the time course of wax formation was also linear up to 30 min.cis-11-Eicosenol was the most effective alcohol substrate whereas tetradecanol, octadecanol, dodecanol,cis-9-octadecanol, andcis-13-eicosenol gave progressively lower activities. Either saturated or unsaturated acyl-CoA with 18 or 20 C-atoms had similar activity. The enzyme was fairly stable at 0 C, less stable at RT and labile above 30 C. Differential centrifugation showed that the 12,000 × g fat pad was the most active in wax formation; to maximize the activity, a 12,000 × g supernatant appeared to be necessary. This factor in the supermatant was thermolabile and nondialyzable.     

Theoretical and Empirical Analysis of ReliefF and RReliefF

Relief algorithms are general and successful attribute estimators. They are able to detect conditional dependencies between attributes and provide a unified view on the attribute estimation in regression and classification. In addition, their quality estimates have a natural interpretation. While they have commonly been viewed as feature subset selection methods that are applied in prepossessing step before a model is learned, they have actually been used successfully in a variety of settings, e.g., to select splits or to guide constructive induction in the building phase of decision or regression tree learning, as the attribute weighting method and also in the inductive logic programming.A broad spectrum of successful uses calls for especially careful investigation of various features Relief algorithms have. In this paper we theoretically and empirically investigate and discuss how and why they work, their theoretical and practical properties, their parameters, what kind of dependencies they detect, how do they scale up to large number of examples and features, how to sample data for them, how robust are they regarding the noise, how irrelevant and redundant attributes influence their output and how different metrics influences them.     

Electrical properties and chemical compatibility of PZT thick film on Ni substrates

The characteristics of Pb(Zr,Ti)O₃(PZT) thick films that were printed and fired on Ni substrates were studied. The dielectric characteristics of samples sintered at 850°C on Ni substrates could not be measured due to the formation of a NiO layer at the Ni/PZT interface. The scanning electron microscope and energy dispersive X-ray analysis of cross-sections of the PZT thick films on Ni substrates, and of a mixture of PZT and NiO powders, fired at 850°C, did not indicate the formation of secondary phases. However, the transmission electron microscopy showed around 8% solid solubility of NiO in the PZT. A new structure with a prefired, Au thick-film layer was designed in order to prevent the diffusion of the NiO to the PZT layer during sintering. The dielectric properties of the PZT layers printed and fired on the Ni substrates with the prefired Au electrode were significantly better than those of the layers on the uncoated substrate, the dielectric losses decreased from 0.23 to 0.05.     

Compact spot-size converters with fiber-matched antiresonant reflecting optical waveguides

We propose a concept for InGaAsP-InP 1.55-microm lasers integrated with spot-size converters based on modal interference between the modes of the structure formed by an active waveguide and an underlying fiber-matched antiresonant reflecting optical waveguide. Simulation results show that the spot-size converters exhibit low transformation loss, and narrowed far-field emission patterns (10 degrees x 20 degrees) and reduce the coupling loss to standard single-mode fibers from 8 to 2.6 dB over lengths approximately 200 microm shorter than the adiabatic concept. A tolerant design to fabrication variations is also proposed, which could be realized by standard processing techniques.     

A characterisation of thick film resistors for strain gauge applications

Some commercial thick film resistors with sheet resistivities from 1 kohm/sq. up to 1 Mohm/sq. were evaluated for strain gauge applications. Temperature coefficients of resistivity, noise indices and gauge factors (GFs) were measured. For the same resistor series GFs and noise indices increase with increasing sheet resistivity. However, both GFs and noise indices are different for resistors with the same nominal sheet resistivity but from different resistor series. The results indicated that the microstructure rather than the different chemical composition of the conductive phase in thick film resistors is the primary reason for the different gauge factors.     

Usability evaluation of anti-phishing toolbars

Phishing is considered as one of the most serious threats for the Internet and e-commerce. Phishing attacks abuse trust with the help of deceptive e-mails, fraudulent web sites and malware. In order to prevent phishing attacks some organizations have implemented Internet browser toolbars for identifying deceptive activities. However, the levels of usability and user interfaces are varying. Some of the toolbars have obvious usability problems, which can affect the performance of these toolbars ultimately. For the sake of future improvement, usability evaluation is indispensable. We will discuss usability of five typical anti-phishing toolbars: built-in phishing prevention in the Internet Explorer 7.0, Google toolbar, Netcraft Anti-phishing toolbar and SpoofGuard. In addition, we included Internet Explorer plug-in we have developed, Anti-phishing IEPlug. Our hypothesis was that usability of anti-phishing toolbars, and as a consequence also security of the toolbars, could be improved. Indeed, according to the heuristic usability evaluation, a number of usability issues were found. In this article, we will describe the anti-phishing toolbars, we will discuss anti-phishing toolbar usability evaluation approach and we will present our findings. Finally, we will propose advices for improving usability of anti-phishing toolbars, including three key components of anti-phishing client side applications (main user interface, critical warnings and the help system). For example, we found that in the main user interface it is important to keep the user informed and organize settings accordingly to a proper usability design. In addition, all the critical warnings an anti-phishing toolbar shows should be well designed. Furthermore, we found that the help system should be built to assist users to learn about phishing prevention as well as how to identify fraud attempts by themselves. One result of our research is also a classification of anti-phishing toolbar applications. Linfeng Li is a student at the University of Tampere, Finland. Marko Helenius is Assistant Professor at the Department of Computer Sciences, University of Tampere, Finland.