An expert system for automated recognition of patients with obstructive sleep apnea using electrocardiogram recordings

Obstructive sleep apnea (OSA) is a highly prevalent sleep disorder. The traditional diagnosis methods of the disorder are cumbersome and expensive. The ability to automatically identify OSA from electrocardiogram (ECG) recordings is important for clinical diagnosis and treatment. In this study, we proposed an expert system based on discrete wavelet transform (DWT), fast-Fourier transform (FFT) and least squares support vector machine (LS-SVM) for the automatic recognition of patients with OSA from nocturnal ECG recordings. Thirty ECG recordings collected from normal subjects and subjects with sleep apnea, each of approximately 8 h in duration, were used throughout the study. The proposed OSA recognition system comprises three stages. In the first stage, an algorithm based on DWT was used to analyze ECG recordings for the detection of heart rate variability (HRV) and ECG-derived respiration (EDR) changes. In the second stage, an FFT based power spectral density (PSD) method was used for feature extraction from HRV and EDR changes. Then, a hill-climbing feature selection algorithm was used to identify the best features that improve classification performance. In the third stage, the obtained features were used as input patterns of the LS-SVM classifier. Using the cross-validation method, the accuracy of the developed system was found to be 100% for using a subset of selected combination of HRV and EDR features. The results confirmed that the proposed expert system has potential for recognition of patients with suspected OSA by using ECG recordings.     

Pitch angle control in wind turbines above the rated wind speed by multi-layer perceptron and radial basis function neural networks

In wind energy conversion systems, one of the operational problems is the changeability and discontinuity of wind. In most cases, wind speed can fluctuate rapidly. Hence, quality of produced energy becomes an important problem in wind energy conversion plants. Several control techniques have been applied to improve the quality of power generated from wind turbines. Pitch control is the most efficient and popular power control method, especially for variable-speed wind turbines. It is a useful method for power regulation above the rated wind speed. This paper proposes an artificial neural network-based pitch angle controller for wind turbines. In the simulations, a variable-speed wind turbine is modeled, and its operation is observed by using two types of artificial neural network controllers. These are multi-layer perceptrons with back propagation learning algorithm and radial basis function network. It is shown that the power output was successfully regulated during high wind speed, and as a result overloading or outage of the wind turbine was prevented.     

Prediction of performance and exhaust emissions of a diesel engine fueled with biodiesel produced from waste frying palm oil

Biodiesel is receiving increasing attention each passing day because of its fuel properties and compatibility with the petroleum-based diesel fuel (PBDF). Therefore, in this study, the prediction of the engine performance and exhaust emissions is carried out for five different neural networks to define how the inputs affect the outputs using the biodiesel blends produced from waste frying palm oil. PBDF, B100, and biodiesel blends with PBDF, which are 50% (B50), 20% (B20) and 5% (B5), were used to measure the engine performance and exhaust emissions for different engine speeds at full load conditions. Using the artificial neural network (ANN) model, the performance and exhaust emissions of a diesel engine have been predicted for biodiesel blends. According to the results, the fifth network is sufficient for all the outputs. In the fifth network, fuel properties, engine speed, and environmental conditions are taken as the input parameters, while the values of flow rates, maximum injection pressure, emissions, engine load, maximum cylinder gas pressure, and thermal efficiency are used as the output parameters. For all the networks, the learning algorithm called back-propagation was applied for a single hidden layer. Scaled conjugate gradient (SCG) and Levenberg–Marquardt (LM) have been used for the variants of the algorithm, and the formulations for outputs obtained from the weights are given in this study. The fifth network has produced R² values of 0.99, and the mean % errors are smaller than five except for some emissions. Higher mean errors are obtained for the emissions such as CO, NO_x and UHC. The complexity of the burning process and the measurement errors in the experimental study can cause higher mean errors.     

PETOOL: MATLAB-based one-way and two-way split-step parabolic equation tool for radiowave propagation over variable terrain

A MATLAB-based one-way and two-way split-step parabolic equation software tool (PETOOL) has been developed with a user-friendly graphical user interface (GUI) for the analysis and visualization of radio-wave propagation over variable terrain and through homogeneous and inhomogeneous atmosphere. The tool has a unique feature over existing one-way parabolic equation (PE)-based codes, because it utilizes the two-way split-step parabolic equation (SSPE) approach with wide-angle propagator, which is a recursive forward–backward algorithm to incorporate both forward and backward waves into the solution in the presence of variable terrain. First, the formulation of the classical one-way SSPE and the relatively-novel two-way SSPE is presented, with particular emphasis on their capabilities and the limitations. Next, the structure and the GUI capabilities of the PETOOL software tool are discussed in detail. The calibration of PETOOL is performed and demonstrated via analytical comparisons and/or representative canonical tests performed against the Geometric Optic (GO) + Uniform Theory of Diffraction (UTD). The tool can be used for research and/or educational purposes to investigate the effects of a variety of user-defined terrain and range-dependent refractivity profiles in electromagnetic wave propagation.

Program summary

Program title: PETOOL (Parabolic Equation Toolbox)Catalogue identifier: AEJS_v1_0Program summary URL:http://cpc.cs.qub.ac.uk/summaries/AEJS_v1_0.htmlProgram obtainable from: CPC Program Library, Queen?s University, Belfast, N. IrelandLicensing provisions: Standard CPC licence, http://cpc.cs.qub.ac.uk/licence/licence.htmlNo. of lines in distributed program, including test data, etc.: 143 349No. of bytes in distributed program, including test data, etc.: 23 280 251Distribution format: tar.gzProgramming language: MATLAB (MathWorks Inc.) 2010a. Partial Differential Toolbox and Curve Fitting Toolbox requiredComputer: PCOperating system: Windows XP and VistaClassification: 10Nature of problem: Simulation of radio-wave propagation over variable terrain on the Earth?s surface, and through homogeneous and inhomogeneous atmosphere.Solution method: The program implements one-way and two-way Split-Step Parabolic Equation (SSPE) algorithm, with wide-angle propagator. The SSPE is, in general, an initial-value problem starting from a reference range (typically from an antenna), and marching out in range by obtaining the field along the vertical direction at each range step, through the use of step-by-step Fourier transformations. The two-way algorithm incorporates the backward-propagating waves into the standard one-way SSPE by utilizing an iterative forward–backward scheme for modeling multipath effects over a staircase-approximated terrain.Unusual features: This is the first software package implementing a recursive forward–backward SSPE algorithm to account for the multipath effects during radio-wave propagation, and enabling the user to easily analyze and visualize the results of the two-way propagation with GUI capabilities.Running time: Problem dependent. Typically, it is about 1.5 ms (for conducting ground) and 4 ms (for lossy ground) per range step for a vertical field profile of vector length 1500, on Intel Core 2 Duo 1.6 GHz with 2 GB RAM under Windows Vista.     

Contribution of laser microdissection-based technology to proteomic analysis in hepatocellular carcinoma developing on cirrhosis

Hepatocellular carcinoma (HCC) is a major cause of cancer worldwide. Proteomic studies provide opportunities to uncover targets for the diagnosis and treatment of this disease. However, in HCC developing in a setting of cirrhosis, the detection of proteome alterations may be hampered by the increased cellular heterogeneity of tissue when analysing global liver homogenates. The aim of this study was to evaluate whether the identification of proteome alterations in these HCC cases was improved when the differential protein profile between tumour and non-tumour areas of liver was determined using hepatocytes isolated by laser microdissection (LM). Differential profiles established with LM-hepatocytes and liver section homogenates using 2-DE and MS exhibited noticeable differences: 30% of the protein spots with deregulated expression in tumorous LM-samples did not display any modification in homogenates; conversely 15% of proteins altered in tumorous homogenates were not impaired in LM-hepatocytes. These alterations resulted from the presence in cirrhotic liver of fibrotic stroma which displayed a protein pattern different from that determined in LM-hepatocytes. In conclusion, our data demonstrate the interest of LM in distinguishing between fibrotic and hepatocyte proteome alterations and thus the benefit of LM to proteome studies of HCC developing in a context of cirrhosis.     

Determination of optimum pH and temperature for pasteurization of citrus juices by response surface methodology

Summary Optimization of microbial death, enzyme inactivation and vitamin C retention during pasteurization of pH-adjusted orange juice is discussed free of equipmentdependent parameters such as the heating lag. The pH-temperature optimum was determined by response surface methodology in the range of 65° C–75° C and pH 2.5–4.0. The results implied that there was no pectinesterase activity below pH 3.5.Leuconostoc mesenteroides had its maximum and minimum thermal resistance at pH 3.5 and pH 2.7, respectively. For an ideal theoretical process requiring four log cycles of microbial reduction the optimum pasteurization conditions were 12 min at 75° C and pH 2.7.

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Bestimmung der optimalen Temperatur- und pH-Wert-Bedingungen für die Pasteurisierung von Citrussäften mit der response surface-Methode

Zusammenfassung Die Optimierung der mikrobiellen Abtötung, Enzyminaktivierung und Vitamin-C-Retention während der Pasteurisierung von Orangensaft mit verschiedenen pH-Werten wird, frei von Anlageneinflüssen, wie z. B. Erhitzungsverzögerungen, diskutiert. Das Temperatur-pH-Wert-Optimum wurde mit der response surface-Methode im Temperaturbereich von 65 bis 75 °C und pH-Werten zwischen 2,5 und 4,0 untersucht. Die Ergebnisse lassen darauf schließen, daß unter pH 3,5 keine Pectinesteraseaktivität mehr vorliegt.Leuconostoc mesentroides wies bei pH 2,7 minimale und bei pH 3,5 maximale Hitzeresistenz auf. In einem idealen theoretischen Pasteurisierungsprozeß, der eine Reduzierung der mikrobiellen Belastung um vier Größenordnungen erfordert, liegen die optimalen Bedingungen bei 12 min, 75 °C und einem pH-Wert von 2,7.

     

Ranking alternatives in a preferential voting system using fuzzy concepts and data envelopment analysis

In this paper, a new method for aggregating the opinions of experts in a preferential voting system is proposed. The method, which uses fuzzy concept in handling crisp data, is computationally efficient and is able to completely rank the alternatives. Through this method, the number of votes for certain rank position that each alternative receives are first grouped together to form fuzzy numbers. The nearest point to a fuzzy number concept is then used to introduce an artificial ideal alternative. Data envelopment analysis is next used to find the efficiency scores of the alternatives in a pair-wise comparison with the artificial ideal alternative. Alternatives are rank based on these efficiency scores. If the alternatives are not completely ranked, a weight restriction method also based on fuzzy concept is used on the un-discriminated alternatives until they are completely ranked. Two examples are given for illustration of the method.     

An Analytical Approach to the Concept of Counter-UA Operations (CUAOPS)

Unmanned Aircraft (UA) have become an integral part of the present-day joint air operations. UA have potential to be employed across the full spectrum of Air Force functions. On the other hand, UA technology could be a subject of an asymmetric use by state actors in high or low density conflict, and/or by non-state actors in many ways including terrorism, drug smuggling, and limited attack with unconventional payloads i.e. biological or chemical agents. Therefore countering the threat associated with the hostile UA use could be necessary in the future. First part of the research revealed that UA can be a threat in the future. In the second part of the research, the SWOT (Strengths-Weaknesses-Opportunities-Threats) analysis supplemented with the Tree analysis (SWOT+Tree) provided a broader look for investigating the factors related to hostile UA use analytically. In literature, there is little information about the concepts for CUAOPS. The final goal of the paper is to find possible solutions and means for a better understanding of the nature of CUAOPS.     

Developing robust vision modules for microsystems applications

In this work, several robust vision modules are developed and implemented for fully automated micromanipulation. These are autofocusing, object and end-effector detection, real-time tracking and optical system calibration modules. An image based visual servoing architecture and a path planning algorithm are also proposed based on the developed vision modules. Experimental results are provided to assess the performance of the proposed visual servoing approach in positioning and trajectory tracking tasks. Proposed path planning algorithm in conjunction with visual servoing imply successful micromanipulation tasks.     

Dynamic hierarchical bandwidth allocation using Russian Doll Model in EPON

This paper demonstrates a new hierarchical Dynamic Bandwidth Allocation algorithm using the Russian Doll Model (RDM) to allocate bandwidth for intra-Optical Network Unit (ONU) in an Ethernet Passive Optical Network (EPON). The allocation of bandwidth is based on the classification and prioritization of service. The algorithm addresses the requests of ONUs and provides differentiated services by balancing priority and fairness. The simulation results show that the proposed algorithm performs well in supporting the triple-play services, i.e. video, voice, and data, as well as making effective adjustment in balancing bandwidth sharing between the ONUs compared with two other existing Dynamic Bandwidth Allocation (DBA) algorithm. The proposed algorithms shows significant performance improvements in terms of bandwidth utilization, packet delay and the fairness.