多样性制导分段进化的基因表达式编程

为了解决基于传统基因表达式编程（GEP）的函数挖掘及其改进算法仍然存在局部优化的缺陷这一问题,提出了以基因组多样性制导的分阶段进化挖掘算法DGGEP。给出了GEP 进化阶段和基因组多样性评估模式的定义;提出了描述进化阶段的进化因子概念和分阶段进化策略;采用动态遗传算子设计和群体规模控制方法,使进化更快速跳出局部最优。实验表明了新算法的有效性,能减少进化停滞代数65％以上,使群体的平均适应度提高12%以上。     

Red Emissive Carbon Dots Prepared from Polymers as an Efficient Nanocarrier for Coptisine Delivery in vivo and in vitro

Negatively charged fluorescent carbon dots (CDs, E_m=608 nm) were hydrothermally prepared from thiophene phenylpropionic acid polymers and then successfully loaded with the positively charged anticancer cargo coptisine, which suffers from poor bioavailability. The formed CD-coptisine complexes were thoroughly characterized by particle size, morphology, drug loading efficiency, drug release, cellular uptake and cellular toxicity in vitro and antitumor activities in vivo. In this nano-carrier system, red emissive CDs possess multiple advantages as follows: 1) high drug loading efficiency (>96 %); 2) sustained drug release; 3) enhanced drug efficacy towards cancer cells; 4) EPR effect; 5) drug release tracing with near-infrared imaging. These properties indicated that red emissive CDs prepared from polymers could be used as a novel drug delivery system with integrated therapeutic and imaging functions in cancer therapy, which are expected to have great potential in future clinical applications.     

排烟高位收水冷却塔设计

本文介绍了排烟高位收水冷却塔探索过程.结合庐江神皖合肥庐江发电厂工程介绍了排烟高位收水冷却塔的斜支柱布置、玻璃钢烟道筒壁支持体系、中央竖井及烟道支架结构及排烟高位收水冷却塔防腐设计.     

严重事故工况下 M31核电机组应急补水设施可用性研究

国内核电厂吸取福岛事故的经验教训,增加了严重事故后应急补水设施,完善了应急补水的相关功能,进一步提高了核电厂的安全水平.对M 310核电机组严重事故状态下的应急补水设施进行技术分析,分析计算结果表明,应急水源到应急补水泵接入点距离过长,水损过大,实际补水压力及流量无法满足设计要求.针对该问题提出一系列设计改进措施,优化改进后的应急补水设施可保证严重事故工况下M 310核电机组应急补水设施的可用性,从而进一步提高核电机组的安全性.     

钨酸镁催化超声降解金橙Ⅱ研究

采用水热法合成了钨酸镁(MgWO4)半导体催化剂,并使用金橙II为有机污染物模型研究了其声催化降解性能.结果表明:MgWO4具有良好的声催化活性,可显著提升超声对有机污染物的降解效果,而且MgWO4具有优秀的可重复利用性能.同时,MgWO4催化超声降解金橙Ⅱ的机理研究表明,产生的活性物质如羟自由基(·OH)、超氧阴离子自由基(·O2-)和空穴(h+)是声催化降解金橙II的主要原因.以上研究结果表明MgWO4作为声催化剂用于处理有机染料废水具有良好的应用前景.     

Crack initiation and propagation induced by inclusions in a nickel-base P/M superalloy under fatigue load

1 IntroductionRecently the key components in advanced aircraftengines are widely made of nickel-base P/M super-alloy. However, non-metallic inclusions are intro-duced into this material during powder metallurgyprocessing. In industry, although many method…     

Preparation and electrochemical performance of nanosized Co3O4 via hydrothermal method

The hydrotalcite-type cobalt compounds were prepared through oxidation of Co（OH）2 gel using NH4OH as precipitating agent and H2O2 as oxidant. These hydrotalcite-type cobalt compounds were transformed into Co3O4 through hydrothermal decomposition with nanostructural deformation. The precursor and product were characterized by Fourier-transform infrared（FT-IR） spectrum, X-ray diffractometry（XRD） and transmission electron microscopy（TEM）. The electrochemical performances of as-prepared nanosized Co3O4 as anode materials in lithium-ion batteries were tested by charge-discharge test in the voltage range of 0-3.0 V. The influence of morphology of Co3O4 particle on the capacity and cycling performance was studied. The results show that the shape and size of the final product can be controlled by altering cobalt sources. The irregular cubic Co3O4 with the average particle size of about 10 nm shows the best electrochemical performance. After 10 charge-discharge cycles, the specific charge capacity retains 555 mA.h/g.     

基于数值模拟的等效拉延筋设计与优化

拉延筋在汽车覆盖件拉深成形中起着十分重要的作用。利用拉延筋可以在较大范围内调节和控制板料的变形程度和变形分布,抑制破裂、起皱、面畸变等多种冲压质量问题的产生。在很多情况下,拉延筋的设置合理与否将决定覆盖件拉深的成败。文章借助eta/DYNAFORM软件,模拟某轿车B柱加强板在无/有拉延筋的模具上进行拉深的全过程,通过模拟结果分析比较,确定拉延筋的合理布局及数量,最后结合正交实验法,优化拉延筋的结构参数。     

金相显微镜三维自动平台

运用现代计算机信息处理技术和自动控制技术，成功地对一台国产显微镜和一台进口显微镜的载物台进行了自动化改造，实现了X、Y方向自动移动和Z方向自动聚焦。本方案改造加工工作小，成本低，不破坏原有显微镜结构，同时还保留了传统的手动调节方法，使用户更容易接受。同时，系统控制软件还中嵌了软件可编程技术，从而简化了操作过程，明显减轻了劳动强度。本系统符合我国国情，是进口设备优良的替代品。