Can we confirm our theories? Can we measure causal effects?: Reply to Kazantzis et al (2001).

Correlations between psychotherapy homework (HW) and recovery from depression (DEP) could be explained by 4 models: (a) HW causes reductions in DEP; (b) reductions in DEP lead to HW compliance; (c) HW and DEP have circular causal effects on each other; and (d) HW and DEP are simultaneously influenced by a 3rd variable, such as motivation. In the D. D. Burns and D. Spangler (2000) (see record 2000-13544-005) study of HW and changes in DEP during the first 12 weeks of therapy using structural equation modeling (SEM), only the first model was consistent with the data. Still, one cannot conclude that a model is "true" or definitely confirm a causal effect, even with experimental designs. The authors recommend SEM for naturalistic and experimental designs. Quality of HW should be included in future research, as N. Kazantzis, K. R. Ronan, and F. Deane (2001) (see record 2001-05666-023) suggest. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Authenticating network attached storage

We present an architecture for network-authenticated disks that implements distributed file systems without file servers or encryption. Our system provides network clients with direct network access to remote storage     

Time-resolved cryotransmission electron microscopy

We describe a new technique, time-resolved cryotransmission electron microscopy (TRC-TEM), that can be used to study changes in microstructure occurring during dynamic processes such as phase transitions and chemical reactions. The sample is prepared on an electron microscope grid maintained at a fixed temperature in a controlled atmosphere. The dynamic process is induced on the grid by a change in pH, salt, or reactant concentration by rapid mixing with appropriate solutions. Alternatively, induction is by rapid change of specimen temperature, or by controlled evaporation of a volatile component. We call such procedures on-the-grid processing. The dynamic process is permitted to run for a defined time and then the thin-film specimen is thermally fixed by plunging into liquid ethane at its freezing point, producing a cryotransmission electron microscopy specimen. By repeating this procedure with varying delays between induction and sample fixation, we can observe transient microstructures. We demonstrate the use of TRC-TEM to study the intermediate structures that form during the transitions between Lα, I_II, and H_II liquid crystalline phases in phospholipid systems. We also identify several other possible applications of the technique.     

TEM study of the recovery process of cyclically deformed MgO single crystals

Single crystals of MgO were subjected to plastic strain-controlled push-pull cyclic deformation at elevated temperatures. Below 400° C the crystals were very brittle and failed with a few fatigue cycles. At 470° C a large number of cycles could be obtained before failure, and the cyclic stress-strain response showed a period of rapid hardening followed by a period of decreasing hardening rate. TEM investigations of the lower temperature samples show structures of isolated dislocation dipoles, multipoles and debris. At 470° C dense bundles of dislocations were observed aligned perpendicular to the Burgers vector direction. The regions between the bundles were relatively dislocation free, but they contained a high density of debris. Bowed out screw dislocations are observed between the edge dislocation bundles, suggesting that screw dislocations were largely mobile. Comparisons are made with the cyclic deformation and structure of fcc metals and other NaCl structure single crystals.     

Effect of intrinsic phase mismatch on linear modulator performanceof the 1×2 directional coupler and Mach-Zehnderinterferometer

The performance of 1×2 directional couplers and Mach-Zehnder interferometers as linear modulators is compared. Models describing the operation of each device, incorporating the intrinsic phase mismatch Δβ₀ which is present in nonideal devices, are developed. Distributions of Δβ₀ are obtained for each device and are shown to be independent of device type. Linear dynamic range and sensitivity measurements showing how Δβ₀ affects performance agree with theory. The additional effect of the coupling coefficient in the 1×2 directional coupler is demonstrated. This information can be used to predict device yield when combined with the measured Δβ₀ distributions     

Anger management style and emotional reactivity to noxious stimuli among chronic pain patients and healthy controls: The role of endogenous opioids.

Objective: Previous work suggests that elevated trait anger-out exacerbates pain responses in part through endogenous opioid dysfunction. The authors examined whether this opioid dysfunction affects not only perceived pain intensity, but also emotional responses to being hurt. Design: 79 chronic low back pain (LBP) patients and 46 healthy controls received opioid blockade (8 mg naloxone i.v.) and placebo in randomized, counterbalanced order in separate sessions. During each session, participants sequentially experienced finger pressure pain and ischemic forearm pain tasks, with emotional state assessed at baseline and postpain. Main Outcome Measures: Blockade effects indexing opioid modulation of emotional reactivity were derived by subtracting placebo from blockade condition emotional reactivity. Results: Significant Participant Type × Anger-Out interactions on blockade effects indicated that in LBP participants but not in controls, greater anger-out was associated with deficient opioid modulation of anxiety, anger, and fear reactivity to noxious stimulation. Across participant types, greater anger-in was associated with impaired opioid modulation of anxiety and fear reactivity. Anger-in opioid effects were partially due to overlap with general negative affect. Conclusions: Opioid dysfunction associated with trait anger-out may affect not only perceived pain intensity, but also pain-related suffering in individuals with chronic pain conditions. Implications for understanding the health effects of anger management styles are discussed. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

应用研究与发展设施

项目地点:美国亚利桑那州旗竿市项目类型:建筑(教育)开工日期:2005年5月该项目获2005年豪瑞可持续建筑大奖赛北美地区提名奖     

Using a chemical equilibrium model to predict amendments required to precipitate phosphorus as struvite in liquid swine manure

Precipitation of phosphate minerals from liquid swine manure is an established means of reducing the orthophosphate (OP) concentration. This project investigated the usefulness of a chemical equilibrium model, Visual Minteq, for prescribing the amendments needed to maximize struvite precipitation from liquid swine manure and thus reduce the OP phosphorus concentration. The actual concentrations of Mg(2+), Ca(2+), K(+), OP, NH(4)(+), alkalinity and pH from a liquid swine manure system were used as inputs to the model. The model was modified to remove species with extremely low formation rates, because they would not significantly precipitate in the reaction occurring in a short retention-time process such as those envisioned for swine manure struvite-formation reactors. Using the model's output, a series of 19-L reactors were used to verify the results. Verification results demonstrated that Visual Minteq can be used to pre-determine the concentration of amendments required to maximize struvite recovery.     

Resolving the origin of the petrogenic hydrocarbon background in Prince William Sound, Alaska

The dominant sources of the petrogenic hydrocarbon background in benthic sediments of Prince William Sound, AK (PWS), site of the 1989 Exxon-Valdez oil spill, are eroding Tertiary shales and residues of natural oil seepage. Mass balance considerations and statistical analyses of hydrocarbon fingerprints independently indicate that coal contributes generally less than 1% of the polycyclic aromatic hydrocarbons (PAH) and chemical biomarkers in this background. This is environmentally significant because of presumed differences in the bioavailability of PAH in coal, seep oil residues, and shales. Coal particles are present in PWS sediments, but their PAH and chemical biomarker contributions are overwhelmed by those of seep oil residues and organic particles from shales of low-to-high thermally maturity. In the late Tertiary or early Quaternary, the currently exposed and eroding shale formations were heated into the oil-generation window and, consequently, are now relatively rich in extractable PAH and chemical biomarkers. The exposed and eroding coals in the area, in contrast, experienced long hot burial and are now thermally overmature with respect to oil generation. The concentrations of thermally sensitive PAH and biomarker compounds in PWS sediments are not consistent with a mature coal origin but are consistent with the low-to-high maturity shales and seep oils in the area.