全文获取类型
收费全文 | 873篇 |
免费 | 0篇 |
国内免费 | 1篇 |
专业分类
电工技术 | 5篇 |
化学工业 | 39篇 |
金属工艺 | 7篇 |
机械仪表 | 1篇 |
轻工业 | 13篇 |
水利工程 | 2篇 |
无线电 | 29篇 |
一般工业技术 | 35篇 |
冶金工业 | 739篇 |
原子能技术 | 2篇 |
自动化技术 | 2篇 |
出版年
2021年 | 1篇 |
2020年 | 1篇 |
2019年 | 2篇 |
2018年 | 1篇 |
2017年 | 1篇 |
2014年 | 2篇 |
2013年 | 12篇 |
2012年 | 4篇 |
2011年 | 5篇 |
2010年 | 4篇 |
2009年 | 5篇 |
2008年 | 2篇 |
2007年 | 2篇 |
2006年 | 7篇 |
2005年 | 8篇 |
2004年 | 4篇 |
2003年 | 7篇 |
2002年 | 2篇 |
2001年 | 2篇 |
2000年 | 9篇 |
1999年 | 23篇 |
1998年 | 193篇 |
1997年 | 121篇 |
1996年 | 66篇 |
1995年 | 47篇 |
1994年 | 46篇 |
1993年 | 53篇 |
1992年 | 11篇 |
1991年 | 17篇 |
1990年 | 20篇 |
1989年 | 23篇 |
1988年 | 18篇 |
1987年 | 11篇 |
1986年 | 11篇 |
1985年 | 18篇 |
1984年 | 1篇 |
1983年 | 4篇 |
1982年 | 7篇 |
1981年 | 5篇 |
1980年 | 5篇 |
1979年 | 4篇 |
1978年 | 3篇 |
1977年 | 25篇 |
1976年 | 53篇 |
1974年 | 1篇 |
1973年 | 1篇 |
1970年 | 1篇 |
1967年 | 1篇 |
1965年 | 3篇 |
1955年 | 1篇 |
排序方式: 共有874条查询结果,搜索用时 0 毫秒
821.
JA Englund WP Glezen C Thompson R Anwaruddin CS Turner GR Siber 《Canadian Metallurgical Quarterly》1997,16(12):1122-1130
OBJECTIVE: To study the kinetics of Haemophilus influenzae type b (Hib)-specific antibody in infants born to mothers immunized with an Hib polysaccharide or one of two Hib conjugate vaccines. STUDY DESIGN: Serum antibody to the polyribosylribitol (PRP) moiety of Hib was measured by radioimmunoassay and enzyme-linked immunosorbent assay at birth and at 2 and 6 months of age in infants born to women immunized with Hib polysaccharide or conjugate vaccine (PRP-D and HbOC). A subset of infants > or = 6 months of age was immunized with Hib conjugate vaccine after licensure of this vaccine for infants. A comparison group of 18 infants born to unimmunized women received the same Hib conjugate vaccine on a similar schedule. RESULTS: Total PRP antibody concentrations were 1.50, 14.4 and 20.4 microg/ml in 2-month-old infants born to mothers immunized with polysaccharide, PRP-D and HbOC vaccines, respectively, and 2.54, 1.35 and 2.46 microg/ml in 6-month-old infants. Infants born to mothers immunized with polysaccharide vaccine had significantly less PRP antibody at 2 months of age but similar antibody concentrations at 6 months of age. Persistence or increases in total PRP antibody during 6 months were noted in 21 of 47 (44.6%) study infants. A subset of study and comparison infants was immunized with a mean of 2.6 doses of Hib vaccines between 6 months and 2 years of age, and all infants had total PRP antibody concentrations > or = 0.15 microg/ml. CONCLUSION: Conjugate Hib vaccines administered during the last trimester of pregnancy resulted in significantly higher PRP antibody titers in infants at birth and 2 months of age than did polysaccharide vaccine. A subset of infants born to immunized mothers was subsequently immunized with Hib conjugate vaccine and had antibody concentrations similar to those in infants born to nonimmunized women. 相似文献
822.
823.
824.
825.
In the discipline of pharmacology, drugs (ligands) are used as tools to elucidate the processes of biological systems. Because of this, pharmacologists strive to delineate all characteristics of drugs. Decades of research have resulted in the proposal that ligands possess two properties that are intrinsic to the ligand and are invariant of the system in which their effects are investigated. These properties are affinity (the capacity of a drug to bind to a receptor) and intrinsic efficacy (the capacity of a drug to activate or inactivate a receptor). Although affinity is a relatively easy parameter to measure with a variety of techniques, ways of quantifying intrinsic efficacy have remained elusive ever since its inception. Furthermore, recent evidence suggests that intrinsic efficacy might not be a single, ligand-dependent parameter but that agonists might have multiple intrinsic efficacies. William Clarke and Richard Bond discuss several reasons why the claim that intrinsic efficacy is a ligand-dependent parameter should be questioned, and the possible impact of these findings. 相似文献
826.
827.
MJ Laughlin DS McGaughey JR Crews NJ Chao D Rizzieri M Ross J Gockerman C Cirrincione D Berry L Mills P Defusco S LeGrand WP Peters JJ Vredenburgh 《Canadian Metallurgical Quarterly》1998,16(3):1008-1012
PURPOSE: To determine the incidence of myelodysplasia (MDS) and/or acute leukemia (AL) in breast cancer patients after high-dose chemotherapy (HDC) with a single conditioning regimen and autologous bone marrow transplant (ABMT), and analyze the cytogenetic abnormalities that arise after HDC. PATIENTS AND METHODS: We retrospectively reviewed the records of 864 breast cancer patients who underwent ABMT at Duke University Medical Center, Durham, NC, from 1985 through 1996 who received the same preparative regimen of cyclophosphamide 1,875 mg/m2 for 3 days, cisplatin 55 mg/m2 for 3 days, and BCNU 600 mg/m2 for 1 day (CPB). Pretransplant cytogenetics were analyzed in all patients and posttransplant cytogenetics were evaluated in four of five patients who developed MDS/AL. RESULTS: Five of 864 patients developed MDS/AL after HDC with CPB and ABMT. The crude cumulative incidence of MDS/AL was 0.58%. The Kaplan-Meier curve shows a 4-year probability of developing MDS/AL of 1.6%. Pretransplant cytogenetics performed on these five patients were all normal. Posttransplant cytogenetics were performed on four of five patients and they were abnormal in all four, although only one patient had the most common cytogenetic abnormality associated with secondary MDS/AL (chromosome 5 and/or 7 abnormality). CONCLUSION: Whereas MDS/AL is a potential complication of HDC with CPB and ABMT, the incidence in this series of patients with breast cancer was relatively low compared with that reported in patients with non-Hodgkin's lymphoma who underwent ABMT. The cytogenetic abnormalities reported in this group of breast cancer patients were not typical of those seen in prior reports of secondary MDS/AL and appear to have occurred after HDC. 相似文献
828.
S Torres JR Ficenec S Mikocki WP Trower KW Lai J LeBritton YC Lin AE Pifer HC Fenker DR Green TF Davenport JH Goldman SL Hagopian JE Lannutti G Canough CC Chang TC Davis RW Joyner JA Poirier CH Georgiopoulos A Napier JM Marraffino JW Waters MS Webster EG Williams JK Woosley 《Canadian Metallurgical Quarterly》1986,34(3):707-710
829.
830.
R Abegg D Bandyopadhyay J Birchall EB Cairns GH Coombes CA Davis NE Davison PP Delheij PW Green LG Greeniaus HP Gubler DC Healey C Lapointe WP Lee WJ McDonald CA Miller GA Moss GR Plattner PR Poffenberger WD Ramsay G Roy J Soukup JP Svenne RR Tkachuk van Oers WT GD Wait YP Zhang 《Canadian Metallurgical Quarterly》1989,39(9):2464-2483