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101.
It is widely accepted that the successful adoption of an information system depends to a great extent on users' perceptions of the information system. It follows then that an understanding of users' cognitive frames should be a key factor in managing the adoption of information systems. To reach such an understanding is not an easy task as cognitive frames are dynamic phenomena. For example, what an individual perceives as ‘ease of use’ and ‘usefulness’ may depend not only on intrinsic qualities of the information system but also on the changing contexts in which the information system is evaluated. This work argues that the management of information systems' adoption is a social and political process in which stakeholders frame and reframe their perceptions of an information system. A case study carried out in a European bank illustrates how the Bank's technical team influenced users' technological frames, including those of senior management in order to ensure a smooth implementation process. In conclusion, the paper introduces a set of theoretical propositions relating to the social and political processes that occur during information systems adoption. 相似文献
102.
103.
Angela M. Gyurko Gregory E. Vignoul John K. Tien Juan M. Sanchez 《Metallurgical and Materials Transactions A》1992,23(11):3073-3076
Engineering, University of Texas at Austin, Austin, TX 78712 While much of the high-temperature intermetallics research has
centered around Ni3Al and other aluminum-based systems, the present study focuses on the Engel-Brewer Ll2 intermetallic Ir3Zr, which has a melting temperature approaching that of ceramics (2280 °C). Due to limited material availability, the technique
of microindentation was used to study both the temperature and time dependence of strength. Because of the widely held belief
that certain mechanical properties of intermetallics scale roughly with temperature, Ir3Zr was expected to exhibit high strength. The microhardness was observed to vary from 225 MPa at room temperature to 75 MPa
at 1400 °C, which is significantly lower than the behavior of Ni3Al. The activation energy for creep was determined to be 467 kJ/mole, and the stress exponent was found to be 18.2. The ordering
energy of this system was calculated to be 0.114 eV. If it can be assumed that high ordering energy correlates to a high antiphase
boundary (APB) energy, then the behavior of this system is consistent with a model that predicts highly glissile dislocation
cores. 相似文献
104.
In response to K. B. Little's (1973) article on the Central Office organization of the American Psychological Association, Ginorio questions whether the distribution of women in the governing body is representative of practices proposed in the Affirmative Action plan of 1973. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
105.
Ganz PJ Bauer MD Sun Y Fieno AM Grant RA Correa PE Laskowski M Saunders CW 《Protein engineering, design & selection : PEDS》2004,17(4):333-339
Protein protease inhibitors could potentially be used to stabilize proteases in commercial products such as liquid laundry detergents. However, many protein protease inhibitors are susceptible to hydrolysis inflicted by the protease. We have engineered Streptomyces subtilisin inhibitor (SSI) to resist proteolysis by adding an interchain disulfide bond and removing a subtilisin cleavage site at leucine 63. When these stabilizing changes were combined with changes to optimize the affinity for subtilisin, the resulting inhibitor provided complete protease stability for at least 5 months at 31 degrees C in a subtilisin-containing liquid laundry detergent and allowed full recovery of the subtilisin activity upon the dilution that occurs in a North American washing machine. 相似文献
106.
107.
Pignatello R Spadaro D Vandelli MA Forni F Puglisi G 《Drug development and industrial pharmacy》2004,30(3):277-288
The present study is a preliminary exploration of the affinity between a carboxylic model drug, the nonsteroidal antiinflammatory agent ibuprofen (IBU) and Eudragit RL100 (RL) polymer. Due to the presence of a variable amount of quaternary ammonium groups in this matrix, physical and chemical interaction with the carboxylic drug can occur, which reinforces its scant mechanical dispersion in the polymer network and can ultimately affect its release profile in vitro and in vivo. To study these aspects, IBU was mixed at increasing weight ratios and in different chemical forms (free acid, sodium salt, and n-butyl ester), to investigate further the role of the carboxylic group in the interaction with the RL polymer. Therefore, IBU-RL solid dispersions (coevaporates) were obtained and fully characterized in the solid state through spectroscopic, calorimetric, and x-ray diffractometric analyses. The in vitro release pattern of the drug, in the different chemical states, was studied for the coevaporates, compared with drug-RL physical mixtures, along with drug adsorption profiles from aqueous solutions on the surface of the polymer granules. 相似文献
108.
Anderson AD Deluga GA Moore JT Vergne MJ Hercules DM Kenik EA Lukehart CM 《Journal of nanoscience and nanotechnology》2004,4(7):809-816
Pt-Re/Vulcan carbon powder nanocomposites have been prepared with total metal loadings of 18 wt.% and 40 wt.% using a new non-cluster (1:1)-PtRe bimetallic precursor as the source of metal. Pt-Re nanoparticles having an average diameter of ca. 6 nm and atomic stoichiometry near 1:1 are formed. TEM, on-particle HR-EDS, and powder XRD data are consistent with the formation of Pt-Re alloy nanoparticles having a hexagonal unit cell with cell constants of a = 2.77 A and c = 4.47 A. A nanocomposite prepared at higher total metal loading under more rigorous thermal treatment also contains Pt-Re alloy nanoparticles having a fcc unit cell structure (a = 3.95 A). The precise dependence of Pt-Re nanocrystal structure on the thermal history of the nanocomposite specimen has not been investigated in detail. While these Pt-Re/carbon nanocomposites are active as anode catalysts in operating direct methanol fuel cells, the measured performance is less than that of commercial Pt-Ru/carbon catalysts and has marginal practical importance. 相似文献
109.
DiFrancesco AM Chiu PC Standley LJ Allen HE Salvito DT 《Environmental science & technology》2004,38(1):194-201
A possible removal mechanism for fragrance materials (FMs) in wastewater is adsorption to sludge, and sludge application to land may be a route through which FMs are released to the soil environment. However, little is known about the concentrations and fate of FMs in soil receiving sludge application. This study was conducted to better understand the dissipation of FMs in sludge-amended soils. We first determined the spiking and extraction efficiencies for 22 FMs in soil and leachate samples. Nine FMs were detected in digested sludges from two wastewater treatment plants in Delaware using these methods. We conducted a 1-year die-away experiment which involved four different soils amended with sludge, with and without spiking of the 22 FMs. The initial dissipation of FMs in all spiked trays was rapid, and only seven FMs remained at concentrations above the quantification limits after 3 months: AHTN, HHCB, musk ketone, musk xylene, acetyl cedrene, OTNE, and DPMI. After 1 year, the only FMs remaining in all spiked trays were musk ketone and AHTN. DPMI was the only FM that leached significantly from the spiked trays, and no FMs were detected in leachate from any unspiked tray. While soil organic matter content affected the dissipation rate in general, different mechanisms (volatilization, transformation, leaching) appeared to be important for different FMs. 相似文献
110.