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101.
Thibaut Crochon Tony Schönherr Chun Li Martin Lévesque 《Mechanics of Time-Dependent Materials》2010,14(4):359-387
This paper presents two new strategies for implementing Schapery-type nonlinearly viscoelastic constitutive theories into
finite element codes. The first strategy uses the original differential equations that lead to the integral formulation of
Schapery-type constitutive theories and Finite Difference (FD) schemes. This strategy is quite different from all the other
strategies found in the literature. The second strategy is an improvement of recursive strategies, used by many authors, based
on the integral formulation of the constitutive theory. The performances of the new algorithms are compared with those of
existing strategies for various load histories and nonlinearities. It is shown that the newly developed strategy based on
FD schemes can exhibit quadratic convergence rate when one time step is stored and 4th order convergence rate when two time
steps are stored, which is a major improvement over the recursive strategies. 相似文献
102.
We report a pulsed-field gradient NMR study of the size of the oil bodies in lettuce seeds. The pulsed-field gradient spin-echo method (PFGSE) was applied to measure the self-diffusion coefficient of triacylglycerol molecules (TAG) inside the oil bodies. The confined nature of TAG diffusion is used to determine the size dispersion of the oil bodies. At long diffusion time, we measure a spin-echo attenuation that is related to the form factor of the confining volumes in the reciprocal q space, where q is proportional to the product of the gradient intensity and the length of the pulse gradient. Specific care was taken in analyzing the influence of the gradient pulse length delta on the shape of the PFGSE decay in order to construct the function corresponding to the short gradient pulse approximation (SGP). The SGP model gives an analytical framework for the PFGSE signal that enables the size distribution of the oil bodies to be determined. The SGP function was unambiguously obtained by varying the gradient pulse length delta in order to linearly extrapolate at delta = 0 the SGP limit. In this work, we also consider the Gaussian phase distribution (GPD) assumption that is often used to analyze confined diffusion experiments. Although the GPD assumption is known to be inaccurate in predicting the fine structure of the PFGSE function in q space, we point out that in the present case it can be used to take into account the finite value of delta. A log-normal distribution of the radius values was assumed in simulating the PFGNMR experiments since this type of distribution is observed in vegetable seeds by transmission electronic microscopy. From a practical and experimental standpoint, the NMR measurements reported here require no specific treatment of the seeds and the size of oil bodies is determined "in situ" on seeds poured into the NMR tube. 相似文献
103.
We present a novel method for a robot to interactively learn, while executing, a joint human–robot task. We consider collaborative tasks realized by a team of a human operator and a robot helper that adapts to the human’s task execution preferences. Different human operators can have different abilities, experiences, and personal preferences so that a particular allocation of activities in the team is preferred over another. Our main goal is to have the robot learn the task and the preferences of the user to provide a more efficient and acceptable joint task execution. We cast concurrent multi-agent collaboration as a semi-Markov decision process and show how to model the team behavior and learn the expected robot behavior. We further propose an interactive learning framework and we evaluate it both in simulation and on a real robotic setup to show the system can effectively learn and adapt to human expectations. 相似文献
104.
Jolien Breukers Karen Ven Caroline Struyfs Louanne Ampofo Iene Rutten Maya Imbrechts Francesca Pollet Julie Van Lent Winnie Kerstens Sam Noppen Dominique Schols Paul De Munter Hendrik Jan Thibaut Karen Vanhoorelbeke Dragana Spasic Paul Declerck Bruno P. A. Cammue Nick Geukens Karin Thevissen Jeroen Lammertyn 《Small Methods》2023,7(3):2201477
Advancements in lab-on-a-chip technologies have revolutionized the single-cell analysis field. However, an accessible platform for in-depth screening and specific retrieval of single cells, which moreover enables studying diverse cell types and performing various downstream analyses, is still lacking. As a solution, FLUIDOT is introduced, a versatile microfluidic platform incorporating customizable microwells, optical tweezers and an interchangeable cell-retrieval system. Thanks to its smart microfluidic design, FLUIDOT is straightforward to fabricate and operate, rendering the technology widely accessible. The performance of FLUIDOT is validated and its versatility is subsequently demonstrated in two applications. First, drug tolerance in yeast cells is studied, resulting in the discovery of two treatment-tolerant populations. Second, B cells from convalescent COVID-19 patients are screened, leading to the discovery of highly affine, in vitro neutralizing monoclonal antibodies against SARS-CoV-2. Owing to its performance, flexibility, and accessibility, it is foreseen that FLUIDOT will enable phenotypic and genotypic analysis of diverse cell samples and thus elucidate unexplored biological questions. 相似文献
105.
Roxane Pétrot Thibaut Devillers Olivier Stéphan Orphée Cugat Caterina Tomba 《Advanced functional materials》2023,33(49):2304445
Two-photon polymerization (2PP) allows precise 3D printing at the micrometer scale, and by associating it with magnetic materials, the creation of remotely actuatable micro-structures. Such structures attract a growing interest for biomedical applications, thanks to their size and to the biocompatibility of some photoresist materials. Gelatin methacryloyl (Gel-MA) is one such material, and can be used to create physiological scaffolds for cell culture. Here, the physico-chemical properties of two resins are exploited, the first being a silica-based hybrid polymer, the OrmoComp, and the second a Gel-MA-based hydrogel. A 2PP manufacturing protocol is defined and designed to print both materials in succession as a single structure, which is then linked to a neodymium-iron-boron (NdFeB) magnetic bead for actuation. By this combination, a magnetically deformable 3D culture substrate is created to study cells in an environment that mimics soft, curved, and dynamic properties of tissues in vivo. The structure is actuated via an external magnetic field and bends back and forth along its longest axis. Lastly, preliminary cell culture trials are conducted showing the proliferation of cells on the structures. 相似文献
106.
Paul Emile Bourgine Emanuele Gaudiello Benjamin Pippenger Claude Jaquiery Thibaut Klein Sebastien Pigeot Atanas Todorov Jr. Sandra Feliciano Andrea Banfi Ivan Martin 《Advanced functional materials》2017,27(7)
Engineered and decellularized extracellular matrices (ECM) are receiving increasing interest in regenerative medicine as materials capable to induce cell growth/differentiation and tissue repair by physiological presentation of embedded cues. However, ECM production/decellularization processes and control over their composition remain primary challenges. This study reports engineering of ECM materials with customized properties, based on genetic manipulation of immortalized and death‐inducible human mesenchymal stromal cells (hMSC), cultured within 3D porous scaffolds under perfusion flow. The strategy allows for robust ECM deposition and subsequent decellularization by deliberate cell‐apoptosis induction. As compared to standard production and freeze/thaw treatment, this grants superior preservation of ECM, leading to enhanced bone formation upon implantation in calvarial defects. Tunability of ECM composition and function is exemplified by modification of the cell line to overexpress vascular endothelial growth factor alpha (VEGF), which results in selective ECM enrichment and superior vasculature recruitment in an ectopic implantation model. hMSC lines culture under perfusion‐flow is pivotal to achieve uniform scaffold decoration with ECM and to streamline the different engineering/decellularization phases in a single environmental chamber. The findings outline the paradigm of combining suitable cell lines and bioreactor systems for generating ECM‐based off‐the‐shelf materials, with custom set of signals designed to activate endogenous regenerative processes. 相似文献
107.
Gbetondji Melaine Armel Nonvide Daniel B. Sarpong George T-M. Kwadzo Henry Anim-Somuah Fulbert Amoussouga Gero 《国际水资源开发杂志》2018,34(6):1001-1021
ABSTRACTThis article examines rice farmers’ perceptions of irrigation and constraints on rice production in the municipality of Malanville, Benin. Farmers’ positive perceptions of irrigation include the use of irrigation for insurance against drought, crop yield improvement, higher income, food security and poverty reduction. Analysis of constraints reveals that farmers face major constraints such as lack of agricultural credit, poor access to production inputs, inadequate knowledge of water resources management, poor access to agricultural information and markets, and flooding of fields. Specific constraints in the irrigation scheme of Malanville include the high cost of irrigation and unavailability of water. 相似文献
108.
109.
Boukas Ioannis Ernst Damien Théate Thibaut Bolland Adrien Huynen Alexandre Buchwald Martin Wynants Christelle Cornélusse Bertrand 《Machine Learning》2021,110(9):2335-2387
Machine Learning - The large integration of variable energy resources is expected to shift a large part of the energy exchanges closer to real-time, where more accurate forecasts are available. In... 相似文献
110.
Nowadays, more and more companies have to use databases in which they store their essential or confidential data for the society like client lists, product specifications, stock situations, etc.. Such pieces of data are the heart of a company and have to be protected. In fact, in the context of economic intelligence, getting such information is quite interesting for competitors who want to know how rival companies work for example. Databases need software to be managed. There is a variety of software, called database management system, which is able to manage database like MySQL, Oracle Database, Microsoft Access, etc... This paper will focus on Microsoft Access 2010 64 bits which is part of the Microsoft Office 2010 suite. Microsoft Access is currently used by small and medium enterprises (SMEs) who have subcontracted the creation of their database to specialized companies. SMEs represent a huge part of the economic area and could be an interesting target because of the large range of activities it gather. This technical paper analyses the Access Security and explains how an attacker could hijack an Access database in order to steal information or to perform malicious actions on the targeted computer. It deals with macro-viruses, still present after many years, and give then the possibility to use them to insert major security weaknesses into Access databases. 相似文献