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81.
Investigations on the formation mechanisms of silicate films on reverse osmosis membranes and their morphological characteristics are presented. Relevant influencing factors on the formation of coatings are considered and the individual mechanisms are described. Furthermore, the essential characterization characteristics for the investigation of silicate coatings are determined, the applied analysis methods are described and an overview of the sample preparation is given. 相似文献
82.
Fani Ziouti Maximilian Rummler Beatrice Steyn Tobias Thiele Anne Seliger Georg N. Duda Bjarne Bogen Bettina M. Willie Franziska Jundt 《International journal of molecular sciences》2021,22(8)
Limiting bone resorption and regenerating bone tissue are treatment goals in myeloma bone disease (MMBD). Physical stimuli such as mechanical loading prevent bone destruction and enhance bone mass in the MOPC315.BM.Luc model of MMBD. It is unknown whether treatment with the Bruton’s tyrosine kinase inhibitor CC-292 (spebrutinib), which regulates osteoclast differentiation and function, augments the anabolic effect of mechanical loading. CC-292 was administered alone and in combination with axial compressive tibial loading in the MOPC315.BM.Luc model for three weeks. However, neither CC-292 alone nor its use in combination with mechanical loading was more effective in reducing osteolytic bone disease or rescuing bone mass than mechanical stimuli alone, as evidenced by microcomputed tomography (microCT) and histomorphometric analysis. Further studies are needed to investigate novel anti-myeloma and anti-resorptive strategies in combination with physical stimuli to improve treatment of MMBD. 相似文献
83.
Johanna Doppler Haider Bettina Gastecker Margit Pohl Patrick Seidler Neesha Kodagoda B. L. William Wong 《Behaviour & Information Technology》2019,38(2):198-215
Visualising how social networks evolve is important in intelligence analysis in order to detect and monitor issues, such as emerging crime patterns or rapidly growing groups of offenders. It remains an open research question how this type of information should be presented for visual exploration. To get a sense of how users work with different types of visualisations, we evaluate a matrix and a node-link diagram in a controlled thinking aloud study. We describe the sense-making strategies that users adopted during explorative and realistic tasks. Thereby, we focus on the user behaviour in switching between the two visualisations and propose a set of nine strategies. Based on a qualitative and quantitative content analysis we show which visualisation supports which strategy better. We find that the two visualisations clearly support intelligence tasks and that for some tasks the combined use is more advantageous than the use of an individual visualisation. 相似文献
84.
Ralf De Wolf Ellen Vanderhoven Bettina Berendt Jo Pierson Tammy Schellens 《Behaviour & Information Technology》2017,36(5):459-469
The increasing popularity of social networking sites has been a source of many privacy concerns. To mitigate these concerns and empower users, different forms of educational and technological solutions have been developed. Developing and evaluating such solutions, however, cannot be considered a neutral process. Instead, it is socially bound and interwoven with norms and values of the researchers. In this contribution, we aim to make the research process and development of privacy solutions more transparent by highlighting questions that should be considered. (1) Which actors are involved in formulating the privacy problem? (2) Is privacy perceived as a human right or as a property right on one’s data? (3) Is informing users of privacy dangers always a good thing? (4) Do we want to influence users’ attitudes and behaviours? (5) Who is the target audience? We argue that these questions can help researchers to better comprehend their own perspective on privacy, that of others, and the influence of the solutions they are developing. In the discussion, we propose a procedure called ‘tool clinics’ for further practical implementations. 相似文献
85.
Exploiting Noncovalent Interactions in an Imine‐Based Covalent Organic Framework for Quercetin Delivery 下载免费PDF全文
86.
Paul Braunger Christian Korunka Bettina Kubicek Hermann Frank Manfred Lueger 《人机工程学与制造业中的人性因素》2015,25(2):198-210
The aim of this study was to investigate safety climate and how it relates to the safety performance of employees from the perspective of safety engineers. Using Griffin and Neal's (2000) safety climate model as a theoretical basis, we hypothesized that the organizational safety climate is a higher‐order construct that relates to the safety compliance of employees and their safety participation via the mediating roles of safety knowledge and safety motivation. Hypotheses were tested among 236 safety engineers working in the wood and metal‐processing industries in Austria. Structural equation modeling (SEM) analysis showed that safety climate is a higher‐order construct comprising manager values, safety communication, safety practices, safety training, and safety equipment. Moreover, from the perspective of safety engineers, the safety climate of the organizations was related to employee safety motivation, which in turn related to their safety compliance and safety participation. In contrast to our assumptions, the safety knowledge of employees was, in the view of safety engineers, neither related to employee safety compliance nor to their safety participation. Multigroup analysis revealed no differences between internally and externally employed safety engineers for these relations. Thus, although the safety climate model was generally confirmed from an engineer's perspective, engineers rated motivational aspects of safety climate is more important compared to knowledge aspects. 相似文献
87.
We investigated the effect of an elevated ambient temperature on performance in a persistence task. The task involved the coding of incorrect symbols and participants were free to decide how long to spend performing this task. Applying a between-subject design, we tested 125 students in an office-like environment in one of the three temperature conditions. The comfort condition (Predicted Mean Vote [PMV] = 0.01) featured an average air temperature of 24 °C. The elevated ambient temperature condition was 28 °C (PMV = 1.17). Condition three employed an airstream of approximately 0.8 m/s, intended to compensate for performance decrements at the elevated air temperature (28 °C, PMV = 0.13), according to Fanger’s thermal comfort equation. Participants in the warm condition were significantly less persistent compared with participants in the control and compensation conditions. As predicted by the thermal comfort equation, the airstream seemed to compensate for the higher temperature. Participants’ persistence in the compensation and comfort conditions did not differ.
Practitioner Summary: A laboratory experiment involving a simulated office environment and three ambient temperature conditions (24 °C, 28 °C and 28 °C plus airstream) showed that persistence at a task is significantly impaired at 28 °C. An airstream of 0.8 m/s at 28 °C compensated for the disinclination to persist with the task. 相似文献
88.
CO oxidation over structured carriers: A comparison of ceramic foams, honeycombs and beads 总被引:1,自引:0,他引:1
Florina Corina Patcas Gerardo Incera Garrido Bettina Kraushaar-Czarnetzki 《Chemical engineering science》2007,62(15):3984-3990
This work aims an experimental comparison of different packings on the basis of their pressure drop, mass and heat transfer properties. Ceramic foams, beads and a honeycomb monolith were used as carriers in the oxidation of carbon monoxide. The carriers were coated with active Pt/SnO2. The CO oxidation rate was measured in the regime of external diffusion control at superficial gas velocities between 1 and 10 m/s. The volumetric rate coefficients and the pressure drop of packings with similar geometric surface area decreased in the sequence particles > foams > honeycomb. The magnitude of the temperature gradient along the catalytic bed decreased as going from honeycomb over larger particles to foams and small particles. Foams were superior over particle beds from the viewpoint of combined high mass transfer and low-pressure drop. The main advantage of foams as compared to honeycomb resided in the radial mixing enabling a better heat transfer to the reactor walls. 相似文献
89.
Karl‐Heinz Wagner Bettina Isnardy Ibrahim Elmadfa 《European Journal of Lipid Science and Technology》2004,106(1):44-51
The antioxidative effects of γ‐ and mainly δ‐tocopherol in a multiphase system were hardly considered up to now. The aim of this study was i) to assess the effects and ii) to follow the degradation of α‐, γ‐ and δ‐tocopherol in concentrations of 0.01%, 0.05%, 0.1% and 0.25% during the oxidation of a 10% purified rapeseed oil triacylglycerol‐in‐water emulsion at 40 °C in the dark for 15 wk in a system containing a low oxygen concentration. Oxidation experiments were performed weekly by assessing the formation of hydroperoxides and hexanal, and the stability of the tocopherols was determined using high‐performance liquid chromatography. Storage tests were conducted with and without the addition of 0.01% α, α′‐azoisobutyronitrile (AIBN), which is a known radical initiator. α‐Tocopherol increased the formation of hydroperoxides in both tests as well as the generation of hexanal when the radical initiator was added; furthermore it was the least stable. γ‐Tocopherol delayed the formation of hexanal and prolonged the stability of the emulsion in a dose‐dependant manner. δ‐Tocopherol was the most stable and also the most effective in delaying lipid oxidation in the emulsions. Each concentration that was tested reduced the rate of hydroperoxide and especially hexanal formation. Hexanal was only formed to a slight extent after 15 wk of oxidation in the test with AIBN and the lowest dose of 0.01% δ‐tocopherol. For all tocopherols, strong correlations were found between tocopherol stability and the extent of oxidation. Results suggest that i) mainly δ‐tocopherol, but also γ‐tocopherol even less pronounced, are very good antioxidants in order to stabilize and prolong the shelf life of oil‐in‐water emulsions, ii) the antioxidative effects were intensified with increasing amounts. 相似文献
90.
Kamal Zellag Bettina Kemme 《The VLDB Journal The International Journal on Very Large Data Bases》2014,23(1):147-172
Modern transaction systems, consisting of an application server tier and a database tier, offer several levels of isolation providing a trade-off between performance and consistency. While it is fairly well known how to identify qualitatively the anomalies that are possible under a certain isolation level, it is much more difficult to detect and quantify such anomalies during run-time of a given application. In this paper, we present a new approach to detect and quantify consistency anomalies for arbitrary multi-tier application running under any isolation levels ensuring at least read committed. In fact, the application can run even under a mixture of isolation levels. Our detection approach can be online or off-line and for each detected anomaly, we identify exactly the transactions and data items involved. Furthermore, we classify the detected anomalies into patterns showing the business methods involved as well as analyzing the types of cycles that occur. Our approach can help designers to either choose an isolation level where the anomalies do not occur or to change the transaction design to avoid the anomalies. Furthermore, we provide an option in which the occurrence of anomalies can be automatically reduced during run-time. To test the effectiveness and efficiency of our approach, we have conducted a set of experiments using a wide range of benchmarks. 相似文献