Censored data are quite common in statistics and have been studied in depth in the last years [for some references, see Powell (J Econom 25(3):303–325, 1984), Murphy et al. (Math Methods Stat 8(3):407–425, 1999), Chay and Powell (J Econ Perspect 15(4):29–42, 2001)]. In this paper, we consider censored high-dimensional data. High-dimensional models are in some way more complex than their low-dimensional versions, therefore some different techniques are required. For the linear case, appropriate estimators based on penalised regression have been developed in the last years [see for example Bickel et al. (Ann Stat 37(4):1705–1732, 2009), Koltchinskii (Bernoulli 15:799–828, 2009)]. In particular, in sparse contexts, the \(l_1\)-penalised regression (also known as LASSO) [see Tibshirani (J R Stat Soc Ser B 58:267–288, 1996), Bühlmann and van de Geer (Statistics for high-dimensional data. Springer, Heidelberg, 2011) and reference therein] performs very well. Only few theoretical work was done to analyse censored linear models in a high-dimensional context. We therefore consider a high-dimensional censored linear model, where the response variable is left censored. We propose a new estimator, which aims to work with high-dimensional linear censored data. Theoretical non-asymptotic oracle inequalities are derived. 相似文献
A method to obtain exponentially accurate approximations to solutions for Dirichlet problems with discontinuous boundary data for Laplace's equation in two dimensions is presented and discussed. Model problems with circular or rectangular boundaries, whose solutions can be obtained by separation of variables involving Fourier series, are discussed in detail. First, the boundary data g is expressed as the sum of a singular function SM, which is a certain linear combination of specially constructed singular basis functions {Sn}, and a function, namely, g-sM, which is much smoother than the original data. The function SM is constructed so that its discontinuities, and those of its first M derivatives, coincide with the corresponding discontinuities of g. The solution u to the boundary-value problem is then expressed as the sum of a linear combination of the harmonic extensions { n} of {Sn}, and a function v, which satisfies the boundary condition v=g-SM. Since the boundary data for v has at least M continuous derivatives, the partial sum approximations for v obtained by separation of variables converge much faster than the corresponding partial sum approximations for u. Formally, by letting N, the number of terms retained in the solution for v, be proportional to M, a sequence of approximations can be constructed which converges to u exponentially in the maximum norm, as M . In particular, this implies that, when g is discontinuous, the unwanted effects of the Gibbs phenomenon can be completely overcome! The method is illustrated by several examples, and some possible applications to related problems are discussed. 相似文献
At the FOM Institute for Plasma Physics “Rijnhuizen”, The Netherlands, the commissioning of a high-power, electrostatic free-electron maser is in progress. The design target is the generation of 1 MW microwave power in the frequency range 130–260 GHz. The foreseen application of this kind of device is as a power source for electron cyclotron applications on magnetically confined plasmas.
The device is driven by a high-power electron beam. For long-pulse operation a low loss current is essential. A 3-A electron beam has been accelerated to energies ranging from 1.35 to 1.7 MeV and transported through the undulator at current losses below 0.02%. Further, it was shown that the beam line accepts an electron energy variation of 5% with fixed beam optics. This is essential for rapid tuning of the microwave frequency, over 10%.
Electron beam simulations have shown to be remarkably accurate both for the prediction of the lens settings and for the intercepted current. The operational settings of the beam line which give the highest current transmission are within a few percent of the simulated values. 相似文献
BACKGROUND: Health care professionals are under increasing pressure to contain the cost of health care. Simultaneously, medical technology continues to advance. Medical institutions must therefore consider the costs and benefits before using a new technology. Using a direct costing system, we determined the cost efficacy of stereotaxy applied to the resection of brain mass lesions. METHODS: Twenty-nine patients underwent a stereotactically guided craniotomy and brain tumor resection. Fifteen of them underwent general and fourteen received local anesthesia. Twelve other patients, comprising a historical reference group, underwent a standard craniotomy and brain tumor resection under general anesthesia. costs were determined for every hospital charge item in all patients. Cost efficiency was then compared between the two groups. RESULTS: Patients treated stereotactically incurred additional costs in frame placement and neuroimaging. These costs were offset by savings in operating room time, patient acuity, length of stay, respiratory care, and medications. Savings were greatest for patients who had local anesthesia. Overall, patients treated by stereotactic craniotomy had a total hospitalization cost of $8,495.19, whereas those treated with standard craniotomy incurred a cost of $11,365.23 (p < 0.001). CONCLUSION: Stereotaxy is cost effective for the surgical treatment of brain tumors. Accurate estimates of cost can justify the use of medical technology. Directly measured cost data is a useful index for any cost containment program. 相似文献
Studied questionnaire responses of 45 members of the Association for Advancement of Behavior Therapy in order to develop a profile of characteristics and practices of behavior therapists. Findings indicate that behavior therapists are apparently becoming more flexible in their attitudes and practices and more eclectic. Most Ss have not had personal therapy, use a variety of behavioral techniques, and treat a wide range of adjustment disorders and a diverse set of clients. (13 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
Discusses methods of measuring genital responding in males and females. Advantages and disadvantages of various types of strain gauges, vaginal blood flow monitors, and photoplethysmography are considered, and extragenital measures (e.g., breast volume, EEGs, and muscle tension) are described. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献