全文获取类型
收费全文 | 1052篇 |
免费 | 65篇 |
国内免费 | 1篇 |
专业分类
电工技术 | 8篇 |
综合类 | 8篇 |
化学工业 | 202篇 |
金属工艺 | 16篇 |
机械仪表 | 11篇 |
建筑科学 | 48篇 |
能源动力 | 29篇 |
轻工业 | 239篇 |
水利工程 | 12篇 |
石油天然气 | 2篇 |
无线电 | 131篇 |
一般工业技术 | 175篇 |
冶金工业 | 86篇 |
原子能技术 | 13篇 |
自动化技术 | 138篇 |
出版年
2023年 | 10篇 |
2022年 | 4篇 |
2021年 | 24篇 |
2020年 | 13篇 |
2019年 | 17篇 |
2018年 | 21篇 |
2017年 | 27篇 |
2016年 | 21篇 |
2015年 | 26篇 |
2014年 | 39篇 |
2013年 | 36篇 |
2012年 | 61篇 |
2011年 | 74篇 |
2010年 | 50篇 |
2009年 | 49篇 |
2008年 | 39篇 |
2007年 | 53篇 |
2006年 | 43篇 |
2005年 | 44篇 |
2004年 | 40篇 |
2003年 | 36篇 |
2002年 | 25篇 |
2001年 | 16篇 |
2000年 | 18篇 |
1999年 | 16篇 |
1998年 | 34篇 |
1997年 | 27篇 |
1996年 | 25篇 |
1995年 | 20篇 |
1994年 | 12篇 |
1993年 | 15篇 |
1992年 | 6篇 |
1991年 | 9篇 |
1990年 | 8篇 |
1989年 | 9篇 |
1988年 | 5篇 |
1987年 | 8篇 |
1986年 | 12篇 |
1985年 | 14篇 |
1984年 | 13篇 |
1983年 | 10篇 |
1982年 | 9篇 |
1981年 | 15篇 |
1980年 | 14篇 |
1979年 | 3篇 |
1978年 | 6篇 |
1977年 | 12篇 |
1976年 | 9篇 |
1975年 | 4篇 |
1973年 | 4篇 |
排序方式: 共有1118条查询结果,搜索用时 15 毫秒
71.
Dr. Nikolay B. Anikin Prof. Dr. Rainer Suntz Prof. Dr.‐Ing. Henning Bockhorn 《化学,工程师,技术》2013,85(5):696-704
A recently developed and patented fast tomographic reconstruction system has been applied to detect two‐dimensional distributions of the OH* chemiluminescence in laminar and turbulent flames. This could be achieved by the arrangement at exposure times down to 100 – 200 μs at a spatial resolution of < 1 – 2 mm, even though the concentration of OH* in flames is in the order of some ppb and, therefore, extremely small. Among other things the results provide important information regarding the determination of the heat release rate in flames to predict unstable operating points of gas turbines. 相似文献
72.
Vanessa Kohl Oliver Drews Victor Costina Miriam Bierbaum Ahmed Jawhar Henning Roehl Christel Weiss Susanne Brendel Helga Kleiner Johanna Flach Birgit Spiess Wolfgang Seifarth Daniel Nowak Wolf-Karsten Hofmann Alice Fabarius Henning D. Popp 《International journal of molecular sciences》2021,22(11)
Non-targeted effects (NTE) of ionizing radiation may initiate myeloid neoplasms (MN). Here, protein mediators (I) in irradiated human mesenchymal stromal cells (MSC) as the NTE source, (II) in MSC conditioned supernatant and (III) in human bone marrow CD34+ cells undergoing genotoxic NTE were investigated. Healthy sublethal irradiated MSC showed significantly increased levels of reactive oxygen species. These cells responded by increasing intracellular abundance of proteins involved in proteasomal degradation, protein translation, cytoskeleton dynamics, nucleocytoplasmic shuttling, and those with antioxidant activity. Among the increased proteins were THY1 and GNA11/14, which are signaling proteins with hitherto unknown functions in the radiation response and NTE. In the corresponding MSC conditioned medium, the three chaperones GRP78, CALR, and PDIA3 were increased. Together with GPI, these were the only four altered proteins, which were associated with the observed genotoxic NTE. Healthy CD34+ cells cultured in MSC conditioned medium suffered from more than a six-fold increase in γH2AX focal staining, indicative for DNA double-strand breaks, as well as numerical and structural chromosomal aberrations within three days. At this stage, five proteins were altered, among them IQGAP1, HMGB1, and PA2G4, which are involved in malign development. In summary, our data provide novel insights into three sequential steps of genotoxic signaling from irradiated MSC to CD34+ cells, implicating that induced NTE might initiate the development of MN. 相似文献
73.
Thomas Finke Dominic Lingenfelser Katharina Bindler Ulrich Eisele Henning Bockhorn Gunther Brunklaus 《Journal of the American Ceramic Society》2009,92(8):1823-1830
This paper deals with the specific interaction of the dispersant 3,6,9-trioxadecanoic acid (TODA) with nano-ZrO2 surfaces. Special interest was directed towards degradation behavior of the adsorbates and its influence on dispersant capabilities of TODA regarding stabilization of ethanolic nano-ZrO2 suspensions. ZrO2 adsorption sites and the adsorbates formed are examined by diffuse reflectance infrared Fourier transform spectroscopy, thermal analysis, 1 H-, and 13 C-cross polarization magic angle spinning solid-state nuclear magnetic resonance spectroscopy. 1 H as well as 13 C-chemical shifts and the configurations of the corresponding adsorbed TODA species on zirconia sites are predicted by means of density functional theory quantum chemical calculations for supporting the interpretation of the experimental spectral data obtained. This work shows that combination of analytical and theoretical methods is an effective approach characterizing surface chemical properties of ceramic materials, determining sorption properties of organic process additives, investigating correspondent elementary and degradation reactions as well as clarifying cause-effect relationships in ceramic processes. 相似文献
74.
A top-illuminated GaInAs/InP pin photodiode has been produced in a planar-junction configuration, which combines high reliability (no change in dark current over 4700 h at 175 degrees C) with the widest bandwidth (25 GHz), and highest quantum efficiency (80% at 1.55 mu m), yet reported for this type of device.<> 相似文献
75.
Henning Nielsen 《LWT》2007,40(8):1337-1343
Egg yolk lipids were extracted and fractionated into neutral lipids and phospholipids using acetone followed by ethanol as eluting solvents to a column consisting of spray-dried egg yolk. This technique, named in situ solid phase extraction, can be performed with spray-dried egg yolk due to the properties of this material. The effect of temperature, flowrate and scale has been studied. Results suggest that the methodology is suitable for industrial implementation. 相似文献
76.
Suzelotte Kruijver Lie Zhao Jilt Sietsma Erik Offerman Niels van Dijk Lawrence Margulies Erik Lauridsen Stephan Grigull Henning Poulsen Sybrand van der Zwaag 《国际钢铁研究》2002,73(6-7):236-241
In‐situ deformation tests have been performed on a steel displaying the transformation‐induced plasticity (TRIP) effect, while monitoring the phase transformation by means of X‐ray diffraction. A tensile stress is applied to 0.4 mm thick samples of this steel with mass contents of 0.26 % Si, 1.5 % Mn, and 1.8 % Al in a transmission geometry for a synchrotron‐radiation beam of 25 μm · 25 μm. On the diffraction patterns every grain appears as a discrete spot. The austenite {200} reflections are analysed during this investigation. The diffraction patterns are treated like a powder pattern for five different η‐angles, with η representing the angle between the tensile direction and the normal direction of the diffracting {200} planes. The results of the analysis show that η = 0° and η = 90° are the preferential orientations for the transformation to martensite. The Ludwigson and Burger model [9] is used to gain more information about the stress dependence of the deformation induced martensite formation. The microdiffraction patterns also reveal the changes in carbon concentration in austenite at each retained austenite fraction. 相似文献
77.
Andreas Winkel Wibke Dempwolf Eva Gellermann Magdalena Sluszniak Sebastian Grade Wieland Heuer Michael Eisenburger Henning Menzel Meike Stiesch 《International journal of molecular sciences》2015,16(2):4327-4342
Peri-implant infections from bacterial biofilms on artificial surfaces are a common threat to all medical implants. They are a handicap for the patient and can lead to implant failure or even life-threatening complications. New implant surfaces have to be developed to reduce biofilm formation and to improve the long-term prognosis of medical implants. The aim of this study was (1) to develop a new method to test the antibacterial efficacy of implant surfaces by direct surface contact and (2) to elucidate whether an innovative antimicrobial copolymer coating of 4-vinyl-N-hexylpyridinium bromide and dimethyl(2-methacryloyloxyethyl) phosphonate (VP:DMMEP 30:70) on titanium is able to reduce the attachment of bacteria prevalent in peri-implant infections. With a new in vitro model with semi-coated titanium discs, we were able to show a dramatic reduction in the adhesion of various pathogenic bacteria (Streptococcus sanguinis, Escherichia coli, Staphylococcus aureus, Staphylococcus epidermidis), completely independently of effects caused by soluble materials. In contrast, soft tissue cells (human gingival or dermis fibroblasts) were less affected by the same coating, despite a moderate reduction in initial adhesion of gingival fibroblasts. These data confirm the hypothesis that VP:DMMEP 30:70 is a promising antibacterial copolymer that may be of use in several clinical applications. 相似文献
78.
Advanced Mutasynthesis Studies on the Natural α‐Pyrone Antibiotic Myxopyronin from Myxococcus fulvus 下载免费PDF全文
J. Henning Sahner Hilda Sucipto Dr. Silke C. Wenzel Dr. Matthias Groh Prof. Dr. Rolf W. Hartmann Prof. Dr. Rolf Müller 《Chembiochem : a European journal of chemical biology》2015,16(6):946-953
Myxopyronin is a natural α‐pyrone antibiotic from the soil bacterium Myxococcus fulvus Mx f50. Myxopyronin inhibits bacterial RNA polymerase (RNAP) by binding to a part of the enzyme not targeted by the clinically used rifamycins. This mode of action makes myxopyronins promising molecules for the development of novel broad‐spectrum antibacterials. We describe the derivatization of myxopyronins by an advanced mutasynthesis approach as a first step towards this goal. Site‐directed mutagenesis of the biosynthetic machinery was used to block myxopyronin biosynthesis at different stages. The resulting mutants were fed with diverse precursors that mimic the biosynthetic intermediates to restore production. Mutasynthon incorporation and production of novel myxopyronin derivatives were analyzed by HPLC‐MS/MS. This work sets the stage for accessing numerous myxopyronin derivatives, thus significantly expanding the chemical space of f α‐pyrone antibiotics. 相似文献
79.
Mohammed Es‐Souni Martha Es‐Souni Salah Habouti Nicole Pfeiffer Abdelilah Lahmar Matthias Dietze Claus‐Henning Solterbeck 《Advanced functional materials》2010,20(3):377-385
TiO2? Ag‐nanocomposites exhibit various desirable properties that make them suitable for a variety of applications, for example in photocatalysis and as bactericidal coatings. In this work, a new method for processing TiO2? Ag nanocomposites is presented. The nanocomposite films are fabricated from one precursor solution with high silver loading of up to 50%. The resulting films exhibit a microstructure consisting of TiO2? AgxO nanocomposites with a largely XRD‐amorphous TiO2 matrix containing brookite nanocrystals. This specific microstructure absorbs in the visible range so that photoreduction of Ag ions can be accomplished by using visible light. The thin films can be patterned using simple shadow masks. The illuminated areas show a high density of self‐organized nanoparticles (SNPs) and nanorods (SNRs), which are templated by the TiO2 porous network. The particle size can be tuned by varying the irradiation time. Most of the SNPs and SNRs form faceted crystals, which are mostly a combination of {111} and {110}. The application of these films as substrates for surface‐enhanced Raman scattering is shown. Enhancement factors as high as 4.6 × 106 could be obtained using rhodamine 6G dye molecules. More applications should involve photocatalytic water purification using visible light. 相似文献
80.
This study presents the synthesis of a crosslinkable dextran as starting material for the development of new hydrogels as drug delivery system in dental applications. 2‐Hydroxyethyl methacrylate (HEMA) was coupled to dextran after activation with carbonyldiimidazole as monitored by FTIR and 1H‐NMR spectroscopy. The Dex‐HEMA was crosslinked by visible light in the presence of camphorquinone (CQ) as photoinitiator and a coinitiator in a proper solvent. Aliphatic or aromatic amines were used as coinitiators and the content of the coinitiator was varied from 0.25 to 3.0 mol %. Diphenyliodonium chloride was added as a third component to the above photoinitiation system. It was observed that, the degree of swelling decreased upon an increase of Dex‐HEMA concentration and the water content in the solvent system due to formation of more crosslinking points, that is, increasing crosslink density (Px). The type of coinitiator shows a prominent impact on the swelling behavior and crosslinking efficiency of hydrogels. Special cryofixation and cryofracture techniques were used to investigate the surface and interior of swollen Dex‐HEMA hydrogel samples by SEM. © 2010 Wiley Periodicals, Inc. J Appl Polym Sci, 2010 相似文献